Maternity swimming at Misasa Hospital of Okayama University Medical School. -Third report. The physiological changes before and after the maternity swimming-

第一報において妊婦水泳に関する妊婦の認識について報告し，第二報において妊婦水泳の現状とその適応について報告したが，その後も症例は順調に増加しており，現在までの参加人数は49名に達した。今回は妊婦水泳が母体と胎児の循環器系にどのような影響を与えるかを調べるために，妊婦水泳の前後におけるnon stress test（NST）と母体の血圧と脈拍数の変化を分析した。対象は妊娠5カ月以降の21名の正常妊婦とした。1．母体の脈拍数は水泳後に増加するものが約80％と明らかに多かったが，血圧は水泳前後で大きな差はみられなかった。2．NSTでは，水泳後に胎児基準心拍数の増加するものが妊娠中期で55.2％，後期で62.3％と多かった。胎児心拍数のlong term variability（LTV）は水泳後に減少するものが妊娠後期で 48.4％を占めた。3.胎動回数は水泳前後でほぼ一定であった。腹緊回数が水泳後に増加した例が妊娠後期で42.4％を占めた。これらの結果のうち，水泳後の胎児基準心拍数の増加とLTVの減少について生理学的見地より若干の考察を加えた。The physiological changes before and after the maternity swimming were retrospectivelly analyzed in 151 records. Following findings were observed after maternity swimming: 1. An increase in maternal pulse rate was observed in 116 cases (76.8%) out of all the cases. 2. Maternal blood pressure increased in 81 cases (53.6%) and decreased in 60 cases (39.7%). 3. An Increase In baseline of fetal heart rate was found in 92 cases (60.9%). 4. Long term variability (LTV) decreased in 67 case s (44.3%) and increased in 21 cases (13.9%). 5. The number of cases with increased fetal movement was almost similar to the number of cases with decreased movement. 6. The rate of uterine contraction increased in 66 cases (43.7%), but there were no cases to need any treatment. The conclusion was as follows: 1. No dangerous changes were observed in non stress test (NST), maternal pulse rate and maternal blood pressure. 2. The increase of baseline of fetal heart rate and the decrease of LTV were characteristic changes of NST after the maternity swimming

Basaloid squamous cell carcinoma in the nasal cavity treated with proton beam therapy concurrent with cisplatin: a case report

INTRODUCTION: Basaloid squamous cell carcinoma is a rare and aggressive variant of squamous cell carcinoma. Basaloid squamous cell carcinoma is mostly seen in the upper aerodigestive tract and has a propensity for lymph node spread and systemic metastases. Various treatment modalities have been reported, including surgical excision supplemented with radiotherapy/adjuvant chemotherapy. To the best of our knowledge, treatment of nasal basaloid squamous cell carcinoma with proton beam therapy and cisplatin has not been described in the literature. CASE PRESENTATION: We report the case of a 56-year-old Japanese man with locally invasive basaloid squamous cell carcinoma in his right nasal cavity with invasion of the orbit, paranasal sinus, and buccal subcutaneous tissue. He underwent proton beam therapy concurrent with cisplatin. Acute and late side effects did not exceed grade 3. At 24-month follow up, he remains in complete remission. CONCLUSION: Proton beam therapy concurrent with cisplatin may be one choice for locally invasive basaloid squamous cell carcinoma

Construction and commissioning of the compact energy-recovery linac at KEK

Energy-recovery linacs (ERLs) are promising for advanced synchrotron light sources, high-power free electron lasers (FELs), high-brightness gamma-ray sources, and electron–ion colliders. To demonstrate the critical technology of ERL-based light sources, we have designed and constructed a test accelerator, the compact ERL (cERL). Using advanced technology that includes a photocathode direct current (DC) electron gun and two types of 1.3-GHz-frequency superconducting cavities, the cERL was designed to be capable of recirculating low emittance (1 mm mrad) and high average-current (10 mA) electron beams while recovering the beam energy. During initial commissioning, the cERL demonstrated successful recirculation of high-quality beams with normalized transverse emittance of 0.14 mm mrad and momentum spread of 1.2 10−4 (rms) at a beam energy of 20 MeV and bunch charge below 100 fC. Energy recovery in the superconducting main linac was also demonstrated for high-average-current continuous-wave beams. These results constitute an important milestone toward realizing ERL-based light sources

The First Beam Recirculation and Beam Tuning in the Compact ERL at KEK

Superconducting(SC)-linac-based light sources, which can produce ultra-brilliant photon beams in CW operation, are attracting worldwide attention. In KEK, we have been conducting R&D; efforts towards the energy-recovery-linac(ERL)-based light source* since 2006. To demonstrate the key technologies for the ERL, we constructed the Compact ERL (cERL)** from 2009 to 2013. In the cERL, high-brightness CW electron beams are produced using a 500-kV photocathode DC gun. The beams are accelerated using SC cavities, transported through a recirculation loop, decelerated in the SC cavities, and dumped. In the February of 2014, we succeeded in accelerating and recirculating the CW beams of 4.5 micro-amperes in the cERL; the beams were successfully transported from the gun to the beam dump under energy recovery operation in the main linac. Then, precise tuning of beam optics and diagnostics of beam properties are under way. We report our experience on the beam commissioning, as well as the results of initial measurements of beam properties