347 research outputs found
Crystal structure changes in Ni3Al and its anomalous temperature dependence of strength
The existence of a structural transformation in Ni3Al alloys established earlier through X-ray diffraction, dilatometry and TEM investigations are summarised. The results obtained are discussed through a model proposed. The L12 structure appears to transform to another L12 or to a DO22 structure during heating. Such a transformation starts at around 700°C and seems to complete around 1100°C. In the temperature range 700-1100°C both phases coexist. This causes a tetragonal distortion of the L12 lattice giving rise to a tweed morphology in TEM observations. The flow stress studies indicate that the anomalous strengthening behaviour is not only due to the dislocation kind of mechanism as proposed in the literature but also due to the structural changes noticed in this work
Thermal evidence for the structural instability in Ni3 Al alloys
The thermal expansion coefficient (¿) and calorimetric data were obtained as a function of temperature in order to clarify some of the significant variations reported with regard to these values in the literature. Stoichiometric and off-stoichiometric compositions of Ni3Al alloys (with and without boron addition) were investigated. Dilatometric experiments were performed on all the alloys and the ¿ values were estimated over the temperature range from ambient to 1000°C. Two runs were made on each sample under different initial conditions and differences in ¿ values were noticed. The results were analysed based on our earlier X-ray diffraction results. Additional isothermal dilatometric tests were also carried out and a significant volume change was noticed (0.45% contraction) when the alloy quenched from 1000°C was heated to 600°C and held for a long duration. The calorimetric data were obtaindd over the same range of temperature and enthalpy changes, though less distinct, were noticed at around 360, 660 and 900°C. The variations seen further augment our earlier results on the instability of the L12 structure and the existence of a structural transformatio
Optimized biomimetic hair sensor arrays for sensing oscillating air flows
Artificial hair sensor arrays are bio-inspired from flow-sensitive filiform hairs of the crickets, one of nature’s best in sensing small air flows. The presented hair sensor arrays aim to realize higher sensitivities compared to our previous sensor arrays by means of model-based design optimizations and fabricated with advanced MEMS technologies. The artificial hair-sensor arrays display a clear figure-of-eight response and show remarkable sensitivities to oscillating air flows down to 0.85 mm/s surpassing noise levels even at 1 kHz operational bandwidths
Common variable immunodeficiency, impaired neurological development and reduced numbers of T regulatory cells in a 10-year-old boy with a STAT1 gain-of-function mutation
Recently, gain-of-function (GOF) mutations in the gene encoding signal transducer and activator of transcription 1 (STAT1) have been associated with chronic mucocutaneous candidiasis (CMC). This case report describes a 10-year-old boy presenting with signs of common variable immunodeficiency (CVID), failure to thrive, impaired neurological development, and a history of recurrent mucocutaneous Candida infections. Sequencing of the STAT1 gene identified a heterozygous missense mutation in exon 7 encoding the STAT1 coiled-coil domain (c.514T > C, p.Phe172Leu). In addition to hypogammaglobulinemia with B-cell deficiency, and a low percentage of Th17 cells, immunological analysis of the patient revealed a marked depletion of forkhead-box P3+-expressing regulatory T cells (Tregs). In vitro stimulation of T cells from the patient with interferon-α (IFNα) and/or IFNɣ resulted in a significantly increased expression of STAT1-regulated target genes such as MIG1, IRF1, MX1, MCP1/CCL2, IFI-56K, and CXCL10 as compared to IFN-treated cells from a healthy control, while no IFNα/ɣ-mediated up-regulation of the FOXP3 gene was found. These data demonstrate that the STAT1 GOF mutation F172L, which results in impaired stability of the antiparallel STAT1 dimer conformation, is associated with inhibited Treg cell development and neurological symptoms
The Charge Form Factor of the Neutron at Low Momentum Transfer from the Reaction
We report new measurements of the neutron charge form factor at low momentum
transfer using quasielastic electrodisintegration of the deuteron.
Longitudinally polarized electrons at an energy of 850 MeV were scattered from
an isotopically pure, highly polarized deuterium gas target. The scattered
electrons and coincident neutrons were measured by the Bates Large Acceptance
Spectrometer Toroid (BLAST) detector. The neutron form factor ratio
was extracted from the beam-target vector asymmetry
at four-momentum transfers , 0.20, 0.29 and 0.42
(GeV/c).Comment: 5 pages, 3 figures, submitted to Phys. Rev. Let
Measurement of the proton electric to magnetic form factor ratio from \vec ^1H(\vec e, e'p)
We report the first precision measurement of the proton electric to magnetic
form factor ratio from spin-dependent elastic scattering of longitudinally
polarized electrons from a polarized hydrogen internal gas target. The
measurement was performed at the MIT-Bates South Hall Ring over a range of
four-momentum transfer squared from 0.15 to 0.65 (GeV/c).
Significantly improved results on the proton electric and magnetic form factors
are obtained in combination with previous cross-section data on elastic
electron-proton scattering in the same region.Comment: 4 pages, 2 figures, submitted to PR
Excellentieonderwijs: Selectie van studenten en individuele effecten
Item does not contain fulltextIn de periode van medio oktober 2015 tot december 2019 hebben wij onderzoek gedaan naar de effecten van excellentieonderwijs in het Nederlandse hoger onderwijs. Dit onderzoek was onderdeel van het onderzoeksprogramma Excellentie van het Nationaal Regieorgaan Onderwijsonderzoek. In dit rapport presenteren wij twee deelstudies van het bredere onderzoek naar excellentieonderwijs, namelijk op het gebied van (1) selectie van studenten voor excellentieonderwijs, en (2) individuele effecten van deelname aan excellentieonderwijs. De andere deelstudies binnen dit bredere onderzoek (namelijk over uitstralingseffecten van excellentieonderwijs op het reguliere onderwijs en op de reguliere organisatie, en over het werkgeversperspectief op excellentieonderwijs) worden besproken in separate rapporten. Een gezamenlijke korte samenvatting over alle deelstudies binnen dit bredere onderzoek naar excellentieonderwijs wordt even-eens gepresenteerd in een afzonderlijke bijdrage.126 p
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