2,496 research outputs found

    Three method factors explaining the low correlations between assessment center dimension ratings and scores on personality inventories

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    In general, correlations between assessment centre (AC) ratings and personality inventories are low. In this paper, we examine three method factors that may be responsible for these low correlations: differences in (i) rating source (other versus self), (ii) rating domain (general versus specific), and (iii) rating format (multi- versus single item). This study tests whether these three factors diminish correlations between AC exercise ratings and external indicators of similar dimensions. Ratings of personality and performance were combined in an analytical framework following a 2 × 2 × 2 (source, domain, format) completely crossed, within subjects design. Results showed partial support for the influence of each of the three method factors. Implications for future research are discussed. Copyright © 2004 John Wiley & Sons, Ltd

    Counselling in primary care : a systematic review of the evidence

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    Primary objective: To undertake a systematic review which aimed to locate, appraise and synthesise evidence to obtain a reliable overview of the clinical effectiveness, cost-effectiveness and user perspectives regarding counselling in primary care. Main results: Evidence from 26 studies was presented as a narrative synthesis and demonstrated that counselling is effective in the short term, is as effective as CBT with typical heterogeneous primary care populations and more effective than routine primary care for the treatment of non-specific generic psychological problems, anxiety and depression. Counselling may reduce levels of referrals to psychiatric services, but does not appear to reduce medication, the number of GP consultations or overall costs. Patients are highly satisfied with the counselling they have received in primary care and prefer counselling to medication for depression. Conclusions and implications for future research: This review demonstrates the value of counselling as a valid choice for primary care patients and as a broadly effective therapeutic intervention for a wide range of generic psychological conditions presenting in the primary care setting. More rigorous clinical and cost-effectiveness trials are needed together with surveys of more typical users of primary care services

    A more reliable PCR for detection of Mycobacterium tuberculosis in clinical samples

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    Diagnostic techniques based on PCR have two major problems: false-positive reactions due to contamination with DNA fragments from previous PCRs (amplicons) and false-negative reactions caused by inhibitors that interfere with the PCR. We have improved our previously reported PCR based on the amplification of a fragment of the Mycobacterium tuberculosis complex-specific insertion element IS6110 with respect to both problems. False-positive reactions caused by amplicon contamination were prevented by the use of uracil-N-glycosylase and dUTP instead of dTTP. We selected a new set of primers outside the region spanned by the formerly used primers to avoid false-positive reactions caused by dTTP-containing amplicons still present in the laboratory. With this new primer set, 16 copies of the IS6110 insertion element, the equivalent of two bacteria, could be amplified 10(10) times in 40 cycles, resulting in a mean efficiency of 77% per cycle. To detect the presence of inhibitors of the Taq polymerase, which may cause false-negative reactions, part of each sample was spiked with M. tuberculosis DNA. The DNA purification method using guanidinium thiocyanate and diatoms effectively removed most or all inhibitors of the PCR. However, this was not suitable for blood samples, for which we developed a proteinase K treatment followed by phenol-chloroform extraction. This method permitted detection of 20 M. tuberculosis bacteria per ml of whole blood. Various laboratory procedures were introduced to reduce failure or inhibition of PCR and avoid DNA cross contamination. We have tested 218 different clinical specimens obtained from patients suspected of having tuberculosis. The samples included sputum (n=145), tissue biopsy samples (n=25), cerebrospinal fluid (n=15), blood (n=14), pleural fluid (n=9), feces, (n=7), fluid from fistulae (n=2), and pus from a wound (n=1). The results obtained by PCR were consistent with those obtained with culture, which is the "gold standard." We demonstrate that PCR is a useful technique for the rapid diagnosis of tuberculosis at various sites

    Long Term Implications of Climate Change on Crop Planning

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    The effects of climate change have been much speculated on in the past few years. Consequently, there has been intense interest in one of its key issues of food security into the future. This is particularly so given population increase, urban encroachment on arable land, and the degradation of the land itself. Recently, work has been done on predicting precipitation and temperature for the next few decades as well as developing optimisation models for crop planning. Combining these together, this paper examines the effects of climate change on a large food producing region in Australia, the Murrumbidgee Irrigation Area. For time periods between 1991 and 2071 for dry, average and wet years, an analysis is made about the way that crop mixes will need to change to adapt for the effects of climate change. It is found that sustainable crop choices will change into the future, and that large-scale irrigated agriculture may become unviable in the region in all but the wettest years

    Energy dependence of exclusive J/ψJ/\psi photoproduction off protons in ultra-peripheral p-Pb collisions at sNN\sqrt{s_{\rm{NN}}} = 5.02 TeV

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    The ALICE Collaboration has measured the energy dependence of exclusive photoproduction of J/ψJ/\psi vector mesons off proton targets in ultra-peripheral p-Pb collisions at a centre-of-mass energy per nucleon pair sNN=5.02\sqrt{s_{\rm NN}} = 5.02 TeV. The e+^+e−^- and μ+μ−\mu^+\mu^- decay channels are used to measure the cross section as a function of the rapidity of the J/ψJ/\psi in the range −2.5<y<2.7-2.5 < y < 2.7, corresponding to an energy in the γ\gammap centre-of-mass in the interval 40<Wγp<55040 < W_{\gamma\mathrm{p}}<550 GeV. The measurements, which are consistent with a power law dependence of the exclusive J/ψJ/\psi photoproduction cross section, are compared to previous results from HERA and the LHC and to several theoretical models. They are found to be compatible with previous measurements.Comment: 25 pages, 3 captioned figures, 3 tables, authors from page 19, published version, figures at http://alice-publications.web.cern.ch/node/455

    Measurement of the production of charm jets tagged with D0^{0} mesons in pp collisions at s\sqrt{s}= 7 TeV

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    The production of charm jets in proton-proton collisions at a center-of-mass energy of s=7\sqrt{s}=7 TeV was measured with the ALICE detector at the CERN Large Hadron Collider. The measurement is based on a data sample corresponding to a total integrated luminosity of 6.236.23 nb−1{\rm nb}^{-1}, collected using a minimum-bias trigger. Charm jets are identified by the presence of a D0^0 meson among their constituents. The D0^0 mesons are reconstructed from their hadronic decay D0→^0\rightarrowK−π+^{-}\pi^{+}. The D0^0-meson tagged jets are reconstructed using tracks of charged particles (track-based jets) with the anti-kTk_{\mathrm{T}} algorithm in the jet transverse momentum range 5<pT,jetch<305<p_{\rm{T,jet}}^{\mathrm{ch}}<30 GeV/c{\rm GeV/}c and pseudorapidity ∣ηjet∣<0.5|\eta_{\rm jet}|<0.5. The fraction of charged jets containing a D0^0-meson increases with pT,jetchp_{\rm{T,jet}}^{\rm{ch}} from 0.042±0.004 (stat)±0.006 (syst)0.042 \pm 0.004\, \mathrm{(stat)} \pm 0.006\, \mathrm{(syst)} to 0.080±0.009 (stat)±0.008 (syst)0.080 \pm 0.009\, \rm{(stat)} \pm 0.008\, \rm{(syst)}. The distribution of D0^0-meson tagged jets as a function of the jet momentum fraction carried by the D0^0 meson in the direction of the jet axis (z∣∣chz_{||}^{\mathrm{ch}}) is reported for two ranges of jet transverse momenta, 5<pT,jetch<155<p_{\rm{T,jet}}^{\rm{ch}}<15 GeV/c{\rm GeV/}c and 15<pT,jetch<3015<p_{\rm{T,jet}}^{\rm{ch}}<30 GeV/c{\rm GeV/}c in the intervals 0.2<z∣∣ch<1.00.2<z_{||}^{\rm{ch}}<1.0 and 0.4<z∣∣ch<1.00.4<z_{||}^{\rm{ch}}<1.0, respectively. The data are compared with results from Monte Carlo event generators (PYTHIA 6, PYTHIA 8 and Herwig 7) and with a Next-to-Leading-Order perturbative Quantum Chromodynamics calculation, obtained with the POWHEG method and interfaced with PYTHIA 6 for the generation of the parton shower, fragmentation, hadronisation and underlying event.Comment: 29 pages, 8 captioned figures, 3 tables, authors from page 24, published version, figures at http://alice-publications.web.cern.ch/node/525
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