Benzoquinoline amines – Key intermediates for the synthesis of angular and linear dinaphthonaphthyridines

A systematic study on the condensation reaction of 2,4-dichlorobenzo[h]quinoline and naphth-1-ylamine in the presence of CuI as catalyst to functionalised mono- and di-substituted (naphthalen-1-yl)benzo[h]quinoline amines was described. Subsequently these mono- and di-substituted amines on polyphosphoric acid catalysed cyclisation reaction with aromatic/heteroaromatic carboxylic acids led to the construction of angular and linear aromatic/heteroaromatic substituted dinaphthonaphthyridines in good yields

Synthesis and Spectroscopic Distinction of Benzonaphthonaphthyridine and Its Isomer

<div><p></p><p>Distinction of benzo[<i>h</i>]naphtho[1,2-<i>b</i>][1,6]naphthyridine and its isomeric benzo[<i>b</i>]naphtho[1,2-<i>h</i>][1,6]naphthyridine is well explained on the basis of various spectroscopic techniques. Initially these isomers were prepared from their respective chloroquinolines via anilinoquinolines as potential intermediates. Spectroscopic dissimilarities of their precursors and intermediates have also been considered and compared with the final benzonaphthonaphthyridine isomers.</p> </div