Steroids Production by Ovarian Non-functioning Tumors in Postmenopausal Women

Higher serum levels of estrone, estradiol, progesterone and testosterone were observed with a high incidence in patients with ovarian non-functioning tumors in postmenopausal women. Postsurgical decreases of the serum levels of steroids in cases who underwent complete removal of tumor were found in all cases only in estradiol, in some cases in other steroids. The difference of steroid serum levels between cases with tumor volume >1000 cm3 an

ChemInform Abstract: THE EFFECT OF SOLVENT ON COMPETING HYDROPEROXIDE AND DIOXETANE FORMATION ON PHOTO-SENSITIZED OXYGENATION OF OLEFINS

The rates of the competitive photo-sensitized oxygenation of 2-isobutylideneadamantane (1) and 2-propylidene-adamantane (2) with 1, 1-di-t-butyl-2-methoxyethane (3) in various solvents were determined. The rates for 1 and 2 were independent of solvent, whereas that for 3 varied markedly with solvent polarity. Compounds 1 and 2 gave only hydroperoxides while 3 gave dioxetane. These results are interpreted in terms of two competing processes involving little and much charge separation leading to hydroperoxide and dioxetane, respectively.</p

A New Reaction of 1,2-Dioxetanes. Formation of 1,2,4-Trioxanes from Aldehydes

1,2-Dioxetanes bearing different 3-phenoxy substituents add to aldehydes to give 1,2,4-trioxanes in yields of 17–75% depending on the nature of the para-phenyl substituent. Illustrations of this new reaction are described

Reactions of cyclic peroxides with aldehydes and ketones catalysed by trimethylsilyl trifluoromethanesulphonate. An efficient synthesis of 1,2,4-trioxanes

Trimethylsilyl trifluoromethanesulphonate is found to be an efficient catalyst for the reaction of 1,4-endoperoxides and 1,2-dioxetanes with aldehydes and ketones to give 1,2,4-trioxanes in high yields.</p

High-performance liquid chromatography of some novel diastereomeric tricyclic 1,2,4-trioxanes

A series of 4a, 10b-dihydronaphtho-[2,1-e]-1,2,4-trioxanes were examined by h.p.l.c. Compounds existing as a pair of diastereomers are only resolved when hydrogen is a substituent at the C3 position. The separations actually observed may arise from conformational differences rather than simple diastereoisomerism.</p