5,305 research outputs found
New normality axioms and decompositions of normality
Generalizations of normality, called (weakly) (functionally) θ-normal spaces, are introduced and studied. This leads to decompositions of normality. It turns out that every paracompact space is θ-normal. Moreover, every Lindelof space as well as every almost compact space is weakly θ-normal. Preservation of θ-normality and its variants under mappings is studied. This in turn strengthens several known results pertaining to normality
Clinicopathological profile of malaria patients in an Central African United Nations hospital
Background: Malaria is one of the most widespread diseases in the world. It is endemic in 91 countries. Each year 300-500 million cases of malaria are confirmed with 1.5-2.7 million deaths. Malaria is a major public health problem in Africa. A large number of united nations troops are deployed in central Africa making them vulnerable to malaria infection. Present study was undertaken to find out the clinical and laboratory findings of malaria cases in a United Nation’s referral hospital in Central Africa.Methods: It is a retrospective study of 150 confirmed and treated cases of malaria for a period of one year in a referral hospital for peace keeping troops and employees of United Nations in Democratic Republic of Congo (DRC). Patients positive by ICT or slide positive were included. Detailed history, examination and lab features of these patients were recorded and analyzed.Results: A total of 150 patients were included in the study. Out of which 145 patients were of pure P. falciparum malaria, 02 patients had only P. vivax, and 03 patients were having mixed malaria. Fever was the main symptoms found in all patients. Headache was the second most predominant symptoms in (70%) patients. Other signs and symptoms were vomiting (31%), myalgia (38%), jaundice (10%), hepatosplenomegaly (15%), pallor (42%) and decreased urine output (8%). Duration of symptoms was between 4 to 15 days. Thrombocytopenia was observed in 43% patients. Jaundice in (10%), transaminitis in (25%). Anaemia was seen in 53% patients.Conclusions: Malaria was found to be the most common cause of admission in our hospital. It is important to suspect malaria in all persons deployed in DRC and presenting with fever and associated headache, jaundice, transaminitis and thrombocytopenia. Early diagnosis and treatment can be lifesaving to prevent complications and mortality
Purification and characterisation of prolactin from sheep and buffalo pituitaries
A study of the problem of structural variants of proteins and their relative contribution to the expressed immunological and biological activity has been initiated using sheep and buffalo prolactins as models. The feasibility of obtaining immunologically and biologically active prolactin in high yields from the discarded 'acid pellet' of sheep and buffalo pituitaries has been demonstrated. This permits use of the same batch of glands for purifying lutropin, follitropin and prolactin as side fractions. The major component in preparations of buffalo prolactin has a molecular size of 24 kDa. The preparations were active in a radioligand binding inhibition assay and in a rat liver based radioreceptor assay. Charge and size isomers of sheep prolactin and buffalo prolactin have been observed. The reference sheep prolactin did not, in preliminary work, give any indication of being glycosylated. However radioactive sulphate was found to be incorporated into prolactin-rich fractions of sheep and buffalo pituitariesin vitro. By physico-chemical and immunochemical criteria the [35S]-labelled material was similar to standard reference prolactin. The structural implications of sulphation have been probed
Implementing Changes in Marketing Strategy: The Role of Perceived Outcome- and Process-Oriented Supervisory Actions
This study investigates the role of supervisors in implementing changes in marketing strategy. The authors propose that perceptions of outcome-oriented supervisory actions influence salespeople\u27s primary appraisals of a strategic change (i.e., whether the change will affect them) and that perceptions of process-oriented supervisory actions influence salespeople’s secondary appraisals (i.e., whether they can cope with the impact of the change on them). The results from a study of 828 salespeople in 204 branches of a large distributor of industrial goods provide evidence that perceived outcome risk containment and outcome reward emphasis enhance primary appraisals, whereas perceived process risk containment and process reward emphasis enhance secondary appraisals. In turn, the authors find that salespeople\u27s primary and secondary appraisals influence their change implementation behaviors, leading to successful change implementation. Notably, they also find that (outcome and process) risk containment has a greater influence on appraisals of salespeople with a higher performance orientation, but the effects of (outcome and process) reward emphases are invariant across salespeople’s performance orientation. The findings suggest that successful implementation of strategic change may depend not merely or even primarily on giving rewards to salespeople for implementing change but also on limiting salespeople\u27s risks and recognizing them for their change-related efforts
Impact of Ageratum conyzoides L. on the diversity and composition of vegetation in the Shivalik hills of Himachal Pradesh (Northwestern Himalaya), India
The flora of the Shivalik hills of Himachal Pradesh, India is under threat due to the rapid invasion of invasive species. Invasive species means an alien species, which becomes established in natural or semi-natural ecosystems and threatens native biological diversity. In their new regimes they show diverse life forms, habit, morphology, reproductive biology, grow fast, have the ability to grow under different habitats, produce enormous number of very small, light weight seeds that and can-survive in soil for years helping long distance dispersal and spread. They can out-compete native species, reduce wildlife habitat potential, alter natural ecosystem processes and limit overall biodiversity. Ageratum conyzoides is one such widely adaptive weed from sub-tropical America that has entered in the Shivalik hills of Hamrpur district of Himachal Pradesh. It has grown as monocultures, in grasslands, forests, agricultural, plantations and horticultural fields in Himachal Pradesh. Hence, it was decided to evaluate the impact of A. conyzoides on the diversity and floristic compositions of native species. It was found that as compared to control, in the Ageratum invaded area; the average number of plant species has reduced by 32.10%; the α diversity has reduced by 41.21% and the dry biomass of plants has also reduced significantly. It was concluded that invasion of A. conyzoides is drastically affecting the productivity and diversity of the invaded areas in Shivalik hills of Hamirpur district
Role of maternal serum ferritin as a predictive marker in intrauterine growth restriction
Background: Intrauterine growth restriction (IUGR) is most common and distressing complication for both obstetrician and neonatologist. Measurement of maternal serum ferritin has also been used as a predictive marker of increase risk of IUGR. In pregnancy, ferritin level decreases with advancing gestation. Its lowest level is seen around 30-32 weeks of gestational age after which its concentration reaches plateau level.Methods: Total 326 antenatal women enrolled in the study. Maternal serum samples of all women were taken at 25th week and again at 30-32 weeks in trace free mineral evacuated tubes for assessment of serum ferritin by chemiluminescence. Mean of both values was calculated.Results: Mean ferritin value of women with average for gestational age neonates was 15.49 ng/ml and women with growth restricted neonates was 19.71 ng/ml. The women with mean serum ferritin above 20 ng/ml, were 6.26 times more likely to have asymmetrically growth restricted baby and 4.47 times more likely to have a symmetrically growth restricted baby when compared to women with serum ferritin value less then <20 ng/ml.Conclusions: In our study negative correlation was found between the value of serum ferritin and neonatal birth weight. In future large randomized control trial is needed to found association between maternal serum ferritin and IUGR.
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