Managerial versus Production Wages: Offshoring, Country Size and Endowments

In this paper, we explore the role of trade in differentiated final goods as well offshoring of tasks for inequality both within and between countries. We emphasize the distinction between managerial and production labor. Production labor is assumed to be a variable input composed of tradable tasks, while managerial labor is a fixed, non-tradable input. We use a 2-country model recently developed by Grossman & Rossi-Hansberg (2010b) that highlights trade in production task, driven by Marshallian economies of scale. We analyze country size and relative endowment effects on the managerial wage premium as well as on international inequality measured in income per head. We compare these effects in a world where trade is restricted to differentiated final goods with a world with trade in both final goods and production tasks.offshoring, economies of scale, income distribution, international inequality

Links between production systems and transport : the example of German and French industries

Changes in transportation are closely linked to the economic and logistical characteristics of the production system. The aim of this paper is, on the basis of data on the economic context and surveys conducted in France (the 1988 Shipper survey and the 2004 ECHO survey) and in Germany (the 2005 DLR survey), to show the major changes that have occurred in the two countries at both micro- and macro-economic levels and how these have affected transport demand. The first level of analysis relates to changes in the economic fabric. In particular, we have demonstrated the growing proportion of small and medium-sized firms at a time when large production units, which are those that are best able to concentrate their freight and use modes other than the road, are becoming fewer and fewer. At the same time, economic links are becoming more complex and, in the case of France, we have shown the increasing role played by wholesale traders in the distribution of goods. The constant reduction in transport costs and the opening up of markets is another structural factor whose impacts in both France and Germany we have also analysed. In addition to these economic changes, the internal modes of production of firms have also changed. Production is becoming more diversified and Just-in-time practices are spreading. The fragmentation of freight flows is thus occurring both in space and in time, which also has a major effect on the characteristics of the flows generated by firms and changes in transport. In the case of all these changes we have attempted to show the differences and similarities between the ways transport has changed in the two countries.TRANSPORT DE MARCHANDISES ; ALLEMAGNE ; FRANCE

Managerial Versus Production Wages: Offshoring, Country Size and Endowments

We explore the role of trade in differentiated final goods as well ollshoring of tasks for inequality both within and between countries. We emphasize the distinction between managerial and production labor. Managerial labor is a fixed input while production labor is a variable input. Following Grossman & Rossi-Hansberg (2010b) we assume that production labor is composed of tradable tasks, with "Marshallian" economies of scale on the task level. We first identify the key determinants of income distribution in a world where trade is restricted to final goods. We then allow for trade in production tasks, driven by country size as well as relative endowment with managerial and production labor. If the two countries are of equal size and if their relative endowments are not too different, then the task trading equilibrium features equalization of production wages, although the pattern of task trade and managerial wages are indeterminate. For differences in relative endowments beyond a certain threshold level, the trading equilibrium is unique and features one-way trade in line with comparative advantage. Relying on numerical simulations we show that international inequality is affected in a non-monotonic way by the cost of task trade. Comparing orders of magnitude we conclude that offshoring between similar countries only has a small positive effect on the managerial wage premium, compared to offshoring between countries with a different relative endowment

Lokale Wirtschaftsentwicklung zwischen Systemtransformation und Standortwettbewerb - das Beispiel der Stadt Leipzig

Am Beispiel Leipzigs werden die Effekte der strukturellen Veränderungen und der zunehmenden Verschärfung des Standortwettbewerbs untersucht. Leipzig ist von besonderem Interesse, weil die Stadt traditionell ein Ort des Wissens und des Handels war; dies sind Faktoren bzw. Aktivitäten, denen gerade unter den heutigen Bedingungen des Standortwettbewerbs eine besondere Bedeutung zukommt. Aktuell verfügt Leipzig zwar über eine gute Ausstattung bei wichtigen Potenzialfaktoren. Hinsichtlich des wirtschaftlichen Ergebnisses hat die Stadt jedoch bislang nicht wieder die Position erreichen können, welche sie vor dem Zweiten Weltkrieg innehatte. Hierbei spielen die Folgen von Planwirtschaft und Systemtransformation ebenso eine Rolle wie die Veränderungen im Standortwettbewerb. Besonders deutlich wird der Einfluss dieser Veränderungen in Leipzig u.a. darin, dass die Stadt sich - wie andere Städte auch - "moderner" wirtschaftspolitischer Strategien (Clusterförderung, Amenity-Strategie, Metropolregionsstrategie) bedient.The example of Leipzig is used to investigate the effects of structural changes and increasingly intense locational competition. Leipzig is particularly interesting because the city was traditionally a location for knowledge and trade, factors and/or activities that are being assigned particular significance under present day conditions of locational competition. Leipzig is currently well equipped with important potential factors. However, in terms of economic results the city has not yet been able to regain the position it occupied before the Second World War. In this context the consequences of the command economy and system transformation have played just as important a role as the changes in locational competition. The influence of these changes in Leipzig is made particularly clear by, among other things, the way in which the city - in common with other cities too - applies “modern” economic policy strategies (cluster promotion, amenity strategy, metropolitan region strategy)

The mutualism effector MiSSP7 of Laccaria bicolor alters the interactions between the poplar JAZ6 protein and its associated proteins

Despite the pivotal role of jasmonic acid in the outcome of plant-microorganism interactions, JA-signaling components in roots of perennial trees like western balsam poplar (Populus trichocarpa) are poorly characterized. Here we decipher the poplar-root JA-perception complex centered on PtJAZ6, a co-repressor of JA-signaling targeted by the effector protein MiSSP7 from the ectomycorrhizal basidiomycete Laccaria bicolor during symbiotic development. Through protein–protein interaction studies in yeast we determined the poplar root proteins interacting with PtJAZ6. Moreover, we assessed via yeast triple-hybrid how the mutualistic effector MiSSP7 reshapes the association between PtJAZ6 and its partner proteins. In the absence of the symbiotic effector, PtJAZ6 interacts with the transcription factors PtMYC2s and PtJAM1.1. In addition, PtJAZ6 interacts with it-self and with other Populus JAZ proteins. Finally, MiSSP7 strengthens the binding of PtJAZ6 to PtMYC2.1 and antagonizes PtJAZ6 homo-/heterodimerization. We conclude that a symbiotic effector secreted by a mutualistic fungus may promote the symbiotic interaction through altered dynamics of a JA-signaling-associated protein–protein interaction network, maintaining the repression of PtMYC2.1-regulated genes

The low-lying excitations of polydiacetylene

The Pariser-Parr-Pople Hamiltonian is used to calculate and identify the nature of the low-lying vertical transition energies of polydiacetylene. The model is solved using the density matrix renormalisation group method for a fixed acetylenic geometry for chains of up to 102 atoms. The non-linear optical properties of polydiacetylene are considered, which are determined by the third-order susceptibility. The experimental 1Bu data of Giesa and Schultz are used as the geometric model for the calculation. For short chains, the calculated E(1Bu) agrees with the experimental value, within solvation effects (ca. 0.3 eV). The charge gap is used to characterise bound and unbound states. The nBu is above the charge gap and hence a continuum state; the 1Bu, 2Ag and mAg are not and hence are bound excitons. For large chain lengths, the nBu tends towards the charge gap as expected, strongly suggesting that the nBu is the conduction band edge. The conduction band edge for PDA is agreed in the literature to be ca. 3.0 eV. Accounting for the strong polarisation effects of the medium and polaron formation gives our calculated E(nBu) ca. 3.6 eV, with an exciton binding energy of ca. 1.0 eV. The 2Ag state is found to be above the 1Bu, which does not agree with relaxed transition experimental data. However, this could be resolved by including explicit lattice relaxation in the Pariser- Parr-Pople-Peierls model. Particle-hole separation data further suggest that the 1Bu, 2Ag and mAg are bound excitons, and that the nBu is an unbound exciton.Comment: LaTeX, 23 pages, 4 postscript tables and 8 postscript figure

The Swiss Approach - feasibility of a national low-dose CT lung cancer screening program.

BACKGROUND Lung cancer is the leading cause of cancer-related deaths in Switzerland. Despite this, there is no lung cancer screening program in the country. In the United States, low-dose computed tomography (LDCT) lung cancer screening is partially established and endorsed by guidelines. Moreover, evidence is growing that screening reduces lung cancer-related mortality and this was recently shown in a large European randomized controlled trial. Implementation of a lung cancer screening program, however, is challenging and depends on many country-specific factors. The goal of this article is to outline a potential Swiss lung cancer screening program. FRAMEWORK An exhaustive literature review on international screening models as well as interviews and site visits with international experts were initiated. Furthermore, workshops and interviews with national experts and stakeholders were conducted to share experiences and to establish the basis for a national Swiss lung cancer screening program. SCREENING APPROACH General practitioners, pulmonologists and the media should be part of the recruitment process. Decentralisation of the screening might lead to a higher adherence rate. To reduce stigmatisation, the screening should be integrated in a "lung health check". Standardisation and a common quality level are mandatory. The PLCOm2012 risk calculation model with a threshold of 1.5% risk for developing cancer in the next six years should be used in addition to established inclusion criteria. Biennial screening is preferred. LUNG RADS and NELSON+ are applied as classification models for lung nodules. CONCLUSION Based on data from recent studies, literature research, a health technology assessment, the information gained from this project and a pilot study the Swiss Interest Group for lung cancer screening (CH-LSIG) recommends the timely introduction of a systematic lung cancer screening program in Switzerland. The final decision is for the Swiss Cancer Screening Committee to make

A risk score including body mass index, glycated haemoglobin and triglycerides predicts future glycaemic control in people with type 2 diabetes

AimTo identify, predict and validate distinct glycaemic trajectories among patients with newly diagnosed type 2 diabetes treated in primary care, as a first step towards more effective patient-centred care. MethodsWe conducted a retrospective study in two cohorts, using routinely collected individual patient data from primary care practices obtained from two large Dutch diabetes patient registries. Participants included adult patients newly diagnosed with type 2 diabetes between January 2006 and December 2014 (development cohort, n=10528; validation cohort, n=3777). Latent growth mixture modelling identified distinct glycaemic 5-year trajectories. Machine learning models were built to predict the trajectories using easily obtainable patient characteristics in daily clinical practice. ResultsThree different glycaemic trajectories were identified: (1) stable, adequate glycaemic control (76.5% of patients); (2) improved glycaemic control (21.3% of patients); and (3) deteriorated glycaemic control (2.2% of patients). Similar trajectories could be discerned in the validation cohort. Body mass index and glycated haemoglobin and triglyceride levels were the most important predictors of trajectory membership. The predictive model, trained on the development cohort, had a receiver-operating characteristic area under the curve of 0.96 in the validation cohort, indicating excellent accuracy. ConclusionsThe developed model can effectively explain heterogeneity in future glycaemic response of patients with type 2 diabetes. It can therefore be used in clinical practice as a quick and easy tool to provide tailored diabetes care