J1406+0102: Dust Obscured Galaxy Hiding Super Eddington Accretion System with Bright Radio Emission

Recent high-$z$ quasar observations strongly indicate that super-Eddington accretion is a crucial phase to describe the existence of supermassive black holes (SMBHs) with $M_\mathrm{BH} \gtrsim 10^9 M_\odot$ at $z \gtrsim 7$. Motivated by the theoretical suggestion that the super-Eddington phase efficiently produces outflows and jets bright in radio bands, we search and find a super-Eddington radio-loud dust-obscured galaxy (DOG) J1406+0102 at $z=0.236$, through cross-matching of the infrared-bright DOGs of Noboriguchi et al. (2019) with the VLA/FIRST 1.4 GHz radio and the SDSS optical spectral catalog. DOG J1406+0102 shows broad components in the Balmer lines. Assuming those lines are from the broad line region, it gives BH mass estimation of $\log\ (M_\mathrm{BH}/M_\odot)=7.30 \pm 0.25$, and AGN luminosity of $\log (L_\mathrm{bol,[OIII]}/\mathrm{erg}~\mathrm{s}^{-1}) = 45.91\pm0.38$ estimated from the intrinsic [OIII] luminosity, resulting in super-Eddington accretion of $\lambda_\mathrm{Edd}\simeq 3$. We show that 1) DOG J1406+0102 is operating strong AGN feedback: the [OIII] outflow velocity exceeds the escape velocity of the host galaxy halo and the kinetic efficiency is obtained as $\approx$ 8% that can be sufficient to quench the host galaxy, 2) the expected future growth pathway of DOG J1406+0102 would join an over-massive BH trajectory and 3) radio-loud DOGs can provide a significant contribution to the high-energy ($\gtrsim$ 100 TeV) cosmic neutrino background if we assume DOG J1406+0102 as a representative of radio-loud DOGs.Comment: 10 pages, 5 figures, submitted to ApJ

Machine Learning Analysis of Gaze Data for Enhanced Precision in Diagnosing Oral Mucosal Diseases

Uchida S., Hiraoka S.I., Kawamura K., et al. Machine Learning Analysis of Gaze Data for Enhanced Precision in Diagnosing Oral Mucosal Diseases. Journal of Clinical Medicine 13, 136 (2024); https://doi.org/10.3390/jcm13010136.The diagnosis of oral mucosal diseases is a significant challenge due to their diverse differential characteristics. Risk assessment of lesions by visual examination is a complex process due to the lack of definitive guidelines. This study aimed to improve this process by creating a diagnostic algorithm using gaze data acquired during oral mucosal disease examinations. A total of 78 dentists were included in this study. Tobii Pro Nano® (Tobii Technology) was used to acquire gaze data during clinical photographic visual examinations. Advanced analysis tools such as support vector machines and heatmaps were used to visualize the gazing tendencies of a group of skilled oral surgeons, focusing on the number of gazes per region and the gazing time ratios. The preliminary findings showed the possibility of visualizing gazing tendencies and identifying areas of importance for diagnosis. The classification of intraoral photographs based on gross features revealed the existence of an optimal examination method for each category and diagnostically significant areas. This novel approach to analyzing gaze data has the potential to refine diagnostic techniques and increase both accuracy and efficiency

Pathogenicity Induced by Invasive Infection of Streptococcus dysgalactiae subsp. equisimilis in a Mouse Model of Diabetes

Streptococcus dysgalactiae subsp. equisimilis (SDSE) causes severe invasive diseases such as streptococcal toxic shock syndrome, similar to that caused by S. pyogenes (GAS). Invasive SDSE infections are increasing, particularly among patients with diabetes mellitus. Here we investigate the association between the pathogenicity of SDSE and diabetes mellitus in a mouse model, using GAS infection for comparison. Intraperitoneal injection of highly hemolytic SDSE-167 into C57BL6/J mice induced a rapid rise in blood glucose concentrations within 4 h, which was otherwise seen only in mice injected with high doses of hypervirulent GAS mutants. The survival rates of mice injected with SDSE-167 were significantly lower in mice (db/db) with type 2 diabetes than in nondiabetic mice. Injection of db/db mice with SDSE-167 increased the concentrations of cytokines and chemokines, particularly those of interleukin 6 and monocyte chemotactic protein-1. Microarray data indicate that multiple pathways are involved in the pathogenicity of SDSE-167 in db/db mice. These data reveal that the mechanisms underlying streptococcal infection differ between SDSE and GAS

H1821+643: The most X-ray and infrared luminous AGN in the Swift/BAT survey in the process of rapid stellar and supermassive black hole mass assembly

H1821+643 is the most X-ray luminous non-beamed AGN of $L_\mathrm{14-150 keV}= 5.2\times 10^{45}$ erg s$^{-1}$ in the Swift/BAT ultra-hard X-ray survey and it is also a hyper-luminous infrared (IR) galaxy $L_\mathrm{IR} = 10^{13.2} L_\odot$ residing in the center of a massive galaxy cluster, which is a unique environment achieving the rapid mass assembly of black holes (BH) and host galaxies in the local universe. We decompose the X-ray to IR spectral energy distribution (SED) into the AGN and starburst component using the SED fitting tool CIGALE-2022.0 and show that H1821+643 consumes a large amount of cold gas ($\dot{M}_\mathrm{con}$) with star-formation rate of $\log ( \mathrm{SFR}/M_{\odot}~\mathrm{yr}^{-1}) = 3.01 \pm 0.04$ and BH accretion rate of $\log (\dot{M}_\mathrm{BH}/M_{\odot}~\mathrm{yr}^{-1}) = 1.20 \pm 0.05$. This high $\dot{M}_\mathrm{con}$ is larger than the cooling rate ($\dot{M}_\mathrm{cool}$) of the intra-cluster medium (ICM), $\dot{M}_\mathrm{con}/\dot{M}_\mathrm{cool} \gtrsim 1$, which is one to two order magnitude higher than the typical value of other systems, indicating that H1821 provides the unique and extreme environment of rapid gas consumption. We also show that H1821+643 has an efficient cooling path achieving from $10^7$ K to $10^2$ K thanks to [OIII] 63 $\mu \mathrm{m}$, which is a main coolant in low temperature range ($10^4$ K to $10^2$ K) with a cooling rate of $\dot{M}_{\mathrm{cool}}=3.2\times 10^5\ M_{\odot}\mathrm{~yr^{-1}}$, and the star-forming region extends over 40 kpc scale.Comment: 20 pages, 8 figures, accepted for publication in Ap

Black hole mass and Eddington ratio distributions of less-luminous quasars at z∼4z\sim4 in the Subaru Hyper Suprime-Cam Wide field

We investigate the black hole mass function (BHMF) and Eddington ratio distribution function (ERDF) of broad-line AGNs at z=4, based on a sample of 52 quasars with i<23.2 at 3.50 < z < 4.25 from the Hyper Suprime-Cam Subaru Strategic Program (HSC-SSP) S16A-Wide2 dataset, and 1,462 quasars with i<20.2 in the same redshift range from the Sloan Digital Sky Survey (SDSS) DR7 quasar catalog. Virial BH masses of quasars are estimated using the width of the CIV 1549{\AA} line and the continuum luminosity at 1350{\AA}. To obtain the intrinsic broad-line AGN BHMF and ERDF, we correct for the incompleteness in the low-mass and/or low-Eddington-ratio ranges caused by the flux-limited selection. The resulting BHMF is constrained down to $\log M_{\rm BH}/M_{\odot}\sim7.5$. In comparison with broad-line AGN BHMFs at z=2 in the literature, we find that the number density of massive SMBHs peaks at higher redshifts, consistent with the "down-sizing" evolutionary scenario. Additionally, the resulting ERDF shows a negative dependence on BH mass, suggesting more massive SMBHs tend to accrete at lower Eddington ratios at z=4. With the derived intrinsic broad-line AGN BHMF, we also evaluate the active fraction of broad-line AGNs among the entire SMBH population at z=4. The resulting active fraction may suggest a positive dependence on BH mass. Finally, we examine the time evolution of broad-line AGN BHMF between z=4 and 6 through solving the continuity equation. The results suggest that the broad-line AGN BHMFs at z=4-6 only show evolution in their normalization, but with no significant changes in their shape.Comment: 38 pages, 26 figures. Submitted to ApJ. Data is available in https://github.com/wanqqq31/BHMF_hsc_z

A Wide and Deep Exploration of Radio Galaxies with Subaru HSC (WERGS). II. Physical Properties derived from the SED Fitting with Optical, Infrared, and Radio Data

We present physical properties of radio galaxies (RGs) with $f_{\rm 1.4 GHz} >$ 1 mJy discovered by Subaru Hyper Supreme-Cam (HSC) and VLA Faint Images of the Radio Sky at Twenty-Centimeters (FIRST) survey. For 1056 FIRST RGs at $0 < z \leq 1.7$ with HSC counterparts in about 100 deg$^2$, we compiled multi-wavelength data of optical, near-infrared (IR), mid-IR, far-IR, and radio (150 MHz). We derived their color excess ($E (B-V)_{*}$), stellar mass, star formation rate (SFR), IR luminosity, the ratio of IR and radio luminosity ($q_{\rm IR}$), and radio spectral index ($\alpha_{\rm radio}$) that are derived from the SED fitting with CIGALE. We also estimated Eddington ratio based on stellar mass and integration of the best-fit SEDs of AGN component. We found that $E (B-V)_{*}$, SFR, and IR luminosity clearly depend on redshift while stellar mass, $q_{\rm IR}$, and $\alpha_{\rm radio}$ do not significantly depend on redshift. Since optically-faint ($i_{\rm AB} \geq 21.3$) RGs that are newly discovered by our RG survey tend to be high redshift, they tend to not only have a large dust extinction and low stellar mass but also have high SFR and AGN luminosity, high IR luminosity, and high Eddington ratio compared to optically-bright ones. The physical properties of a fraction of RGs in our sample seem to differ from a classical view of RGs with massive stellar mass, low SFR, and low Eddington ratio, demonstrating that our RG survey with HSC and FIRST provides us curious RGs among entire RG population.Comment: 30 pages, 20 figures, and 4 tables, accepted for publication in ApJS. The catalog and SED template of radio galaxies will be accessible through an online servic