Chain configurations in light nuclei

The model of nuclear matter built from alpha-particles is proposed. The strong deformed shape for doubly even N=Z nuclides from carbon to magnesium has been determined according to this model. In this paper we undertake very simple approach, which assumes the existence of low lying chain configurations.Comment: 6 pages, 5 figure

Stress relief as the driving force for self-assembled Bi nanolines

Stress resulting from mismatch between a substrate and an adsorbed material has often been thought to be the driving force for the self-assembly of nanoscale structures. Bi nanolines self-assemble on Si(001), and are remarkable for their straightness and length -- they are often more than 400 nm long, and a kink in a nanoline has never been observed. Through electronic structure calculations, we have found an energetically favourable structure for these nanolines that agrees with our scanning tunneling microscopy and photoemission experiments; the structure has an extremely unusual subsurface structure, comprising a double core of 7-membered rings of silicon. Our proposed structure explains all the observed features of the nanolines, and shows that surface stress resulting from the mismatch between the Bi and the Si substrate are responsible for their self-assembly. This has wider implications for the controlled growth of nanostructures on semiconductor surfaces.Comment: 4 pages, 4 figures, submitted to Phys. Rev. Let

Creation of a brane world with Gauss-Bonnet term

We study a creation of a brane world using an instanton solution. We analyze a brane model with a Gauss-Bonnet term in a bulk spacetime. The curvature of 3-brane is assumed to be closed, flat, or open. We construct instanton solutions with branes for those models, and calculate the value of the actions to discuss an initial state of a brane universe.Comment: 9 pages, 10 figure

Land of the Falling “Poison Pill : Understanding Defensive Measures in Japan on Their Own Terms

Embraced by United States (“U.S.”) managers in the 1980s as a lifeline in a sea of hostile takeovers, the poison pill fundamentally altered the trajectory of American corporate governance. When a hostile takeover wave seemed imminent in Japan in the mid-2000s, Japanese boards appeared to embrace this American invention with equal enthusiasm. Japan's experience should have been a ringing endorsement for the utility of American corporate governance solutions in foreign jurisdictions-but it was not to be. Japan's unique interpretation of the “poison pill” that was so eagerly adopted by Japanese companies in the mid-to-late 2000s has turned out to be nothing like their potent American namesakes-and, in fact, the opposite of what would be expected by leading U.S. academics who have built a cottage industry publishing on the U.S. poison pill. Based on hand collected empirical data, we provide the first in-depth analysis of why Japan’s “poison pill” (defensive measures) is heading towards extinction—a watershed reversal that is unexplained in the Japanese literature and has almost entirely escaped the English language literature. By drawing on our hand-collected data, case studies, and Japanese jurisprudence, we illuminate the unique and untold story of how one of the most discussed mechanisms of corporate governance in the U.S. has worked almost entirely differently when transplanted to Japanese soil—the importance of which is heightened as Japan is by far the largest economy in which the poison pill has been tested outside of the United States. Additionally, our analysis sheds light on the unexpected importance of Japan’s recently implemented corporate governance code and stewardship code—two Western legal transplants that have garnered considerable attention in the English language literature, but which have yet to be evaluated in light of their impact on defensive measures in Japan.Published versionThis work was financially supported by the Japan Society for the Promotion of Science (JSPS) Grant-in-Aid JP18K01336 and by the Centre for Asian Legal Studies at NUS Law

Electronic states and optical properties of PbSe nanorods and nanowires

A theory of the electronic structure and excitonic absorption spectra of PbS and PbSe nanowires and nanorods in the framework of a four-band effective mass model is presented. Calculations conducted for PbSe show that dielectric contrast dramatically strengthens the exciton binding in narrow nanowires and nanorods. However, the self-interaction energies of the electron and hole nearly cancel the Coulomb binding, and as a result the optical absorption spectra are practically unaffected by the strong dielectric contrast between PbSe and the surrounding medium. Measurements of the size-dependent absorption spectra of colloidal PbSe nanorods are also presented. Using room-temperature energy-band parameters extracted from the optical spectra of spherical PbSe nanocrystals, the theory provides good quantitative agreement with the measured spectra.Comment: 35 pages, 12 figure

Antiviral immunity and T-regulatory cell function are retained after selective alloreactive T-cell depletion in both the HLA-identical and HLA-mismatched settings

AbstractNonselective T-cell depletion reduces the incidence of severe graft-versus-host disease after allogeneic hematopoietic stem cell transplantation, but the cost is delayed and disordered antigen-specific immune reconstitution and increased infection. We use a method of selective depletion of alloreactive T cells expressing the activation marker CD69 after coculture with stimulator cells in a modified or standard mixed lymphocyte reaction. The technique has been shown to reduce alloreactivity while retaining third-party responses in vitro and, in a mismatched murine model, led to donor T-cell engraftment with a virtual absence of graft-versus-host disease and increased survival. We show in a human HLA-mismatched and unrelated HLA-identical setting that this technique retains >80% of specific cellular antiviral activity by cytomegalovirus-tetramer analysis and cytomegalovirus/Epstein-Barr virus peptide-stimulated interferon-γ ELISpot assay. Furthermore, CD4+ CD25+ T-regulatory cells are not removed by this method of selective allodepletion and retain their function in suppressing allogeneic proliferative responses. Preservation of antiviral cytotoxic T lymphocytes in selectively allodepleted stem cell grafts would lead to improved antiviral immunity after transplantation. The retention of immunosuppressive CD4+ CD25+ T-regulatory cells could lead to more ordered immune reconstitution and further suppress alloreactive responses after transplantation

Artificial Immune System based on Hybrid and External Memory for Mathematical Function Optimization

Artificial immune system (AIS) is one of the natureinspired algorithm for optimization problem. In AIS, clonal selection algorithm (CSA) is able to improve global searching ability. However, the CSA convergence and accuracy can be further improved because the hypermutation in CSA itself cannot always guarantee a better solution. Alternatively, Genetic Algorithms (GAs) and Particle Swarm Optimization (PSO) have been used efficiently in solving complex optimization problems, but they have a tendency to converge prematurely. Thus, a hybrid PSO-AIS and a new external memory CSA based scheme called EMCSA are proposed. In hybrid PSO-AIS, the good features of PSO and AIS are combined in order to reduce any limitation. Alternatively, EMCSA captures all the best antibodies into the memory in order to enhance global searching capability. In this preliminary study, the results show that the performance of hybrid PSO-AIS compares favourably with other algorithms while EMCSA produced moderate results in most of the simulations

Fermented pumpkin-based beverage inhibits key enzymes of carbohydrate digesting and extenuates postprandial hyperglycemia in type-2 diabetic rats

A novel functional pumpkin-based beverage fermented by Lactobacillus mali K8 (FPJ) was produced. FPJ possessed higher ferric reducing antioxidant power (FRAP, 270.76 μM TE/100 ml) and radical scavenging activity (RSA‒IC50, 7.56 mg ml‒1) compared with non-inoculated control (PJ) (102.99 μM TE/100 ml and IC50 52.78 mg ml‒1). Up to an IC50 of 23.71 and 5.27 mg ml‒1 of α-amylase and α-glucosidase inhibitions were demonstrated by FPJ, close to that of acarbose (IC50 4.86 and 0.048 mg ml‒1, respectively). Oral administration of FPJ significantly lowered post-meal blood glucose levels in low-dose streptozotocin (STZ) and high-fat diet-treated rat – a reduction of incremental areas under the curve 2334 versus 2689 mmol min l‒1. Thus, it may open new dietary measure in managing postprandial hyperglycaemia

Artificial Immune System Based Remainder Method for Multimodal Mathematical Function Optimization

Artificial immune system (AIS) is one of the nature-inspired algorithm for solving optimization problems. In AIS, clonal selection algorithm (CSA) is able to improve global searching ability compare to other meta-heuristic methods. However, the CSA rate of convergence and accuracy can be further improved as the hypermutation in CSA itself cannot always guarantee a better solution. Conversely, Genetic Algorithms (GAs) and Particle Swarm Optimization (PSO) have been used efficiently in solving complex optimization problems, but they have an inclination to converge prematurely. In this work, the CSA is modified using the best solutions for each exposure (iteration) namely Single Best Remainder (SBR) - CSA. Simulation results show that the proposed algorithm is able to enhance the performance of the conventional CSA in terms of accuracy and stability for single objective functions

Antibody Remainder Method Based Artificial Immune System for Mathematical Function Optimization

Artificial immune system (AIS) is one of the natureinspired algorithm for solving optimization problem. In AIS, clonal selection algorithm (CSA) is able to improve global searching ability. However, the CSA convergence and accuracy can be improved further because the hypermutation in CSA itself cannot always guarantee a better solution. Alternatively,Genetic Algorithms (GAs) and Particle Swarm Optimization(PSO) have been used efficiently in solving complex optimization problems, but they have a tendency to converge prematurely. In this study, the CSA is modified using the best solution for each exposure (iteration) namely Single Best Remainder (SBR) CSA. In this study, the results show that the performance of the proposed algorithm (SBR-CSA) compares favourably with other algorithms while Half Best Insertion (HBI) CSA produced moderate results in most of the simulations