1,019 research outputs found
Sigma Model BPS Lumps on Torus
We study doubly periodic Bogomol'nyi-Prasad-Sommerfield (BPS) lumps in
supersymmetric CP^{N-1} non-linear sigma models on a torus T^2. Following the
philosophy of the Harrington-Shepard construction of calorons in Yang-Mills
theory, we obtain the n-lump solutions on compact spaces by suitably arranging
the n-lumps on R^2 at equal intervals. We examine the modular invariance of the
solutions and find that there are no modular invariant solutions for n=1,2 in
this construction.Comment: 15 pages, 3 figures, published versio
Community Knowledge, Perceptions, and Practices Associated with Urogenital Schistosomiasis among School-Aged Children in Zanzibar, United Republic of Tanzania
Background: On the Zanzibar islands, United Republic of Tanzania, elimination of urogenital schistosomiasis is strived for in the coming years. This qualitative study aimed to better understand community knowledge, perceptions, and practices associated with schistosomiasis among school-aged children on Unguja and Pemba islands, in order to inform the development of behavior change interventions contributing to eliminate urogenital schistosomiasis.
Methodology: In 2011, we conducted 35 children’s discussion groups, 41 in-depth interviews with parents and teachers, and 5 focus group discussions with community members in Zanzibar. Using a modified-grounded theory approach, we transcribed and coded the narrative data followed by thematic analysis of the emergent themes.
Principal Findings: Urogenital schistosomiasis is a common experience among children in Zanzibar and typically considered a boys’ disease. Children engage in multiple high-risk behaviors for acquiring schistosomiasis because of poor knowledge on disease transmission, lack of understanding on severity of disease-associated consequences, and lack of alternative options for water related activities of daily living and recreational play. Local primary school teachers had little to no training about the disease and no teaching tools or materials for students.
Conclusions/Significance: Conducting activities in open natural freshwater contaminated by S. haematobium larvae compromises the health of school-aged children in Zanzibar. The perception of urogenital schistosomiasis as a minor illness rather than a serious threat to a child’s well-being contributes to the spread of disease. Understanding community perceptions of disease along with the barriers and facilitators to risk reduction behaviors among children can inform health promotion activities, campaigns, and programs for the prevention, control, and elimination of urogenital schistosomiasis in Zanzibar
Physical trauma and risk of multiple sclerosis: A systematic review and meta-analysis of observational studies
AbstractBackgroundWe aimed to examine physical trauma as a risk factor for the subsequent diagnosis of MS.MethodsWe searched for observational studies that evaluated the risk for developing MS after physical trauma that occurred in childhood (≤20years) or “premorbid” (>20years). We performed a meta-analysis using a random effects model.ResultsWe identified 1362 individual studies, of which 36 case–control studies and 4 cohort studies met the inclusion criteria for the review. In high quality case–control studies, there were statistically significant associations between those sustaining head trauma in childhood (OR=1.27; 95% CI, 1.12–1.44; p<0.001), premorbid head trauma (OR=1.40; 95% CI, 1.08–1.81; p=0.01), and other traumas during childhood (OR=2.31; 95% CI, 1.06–5.04; p=0.04) and the risk of being diagnosed with MS. In lesser quality studies, there was a statistical association between “other traumas” premorbid and spinal injury premorbid. No association was found between spinal injury during childhood, or fractures and burns at any age and the diagnosis of MS. The pooled OR of four cohort studies looking at premorbid head trauma was not statistically significant.ConclusionsThe result of the meta-analyses of high quality case–control studies suggests a statistically significant association between premorbid head trauma and the risk for developing MS. However, cohort studies did not. Future prospective studies that define trauma based on validated instruments, and include frequency of traumas per study participant, are needed
Inelastic Neutron scattering in CeSi_{2-x}Ga_x ferromagnetic Kondo lattice compounds
Inelastic neutron scattering investigation on ferromagnetic Kondo lattice
compounds belonging to CeSi_{2-x}Ga_{x}, x = 0.7, 1.0 and 1.3, system is
reported. The thermal evolution of the quasielastic response shows that the
Kondo interactions dominate over the RKKY interactions with increase in Ga
concentration from 0.7 to 1.3. This is related to the increase in k-f
hybridization with increasing Ga concentration. The high energy response
indicates the ground state to be split by crystal field in all three compounds.
Using the experimental results we have calculated the crystal field parameters
in all three compounds studied here.Comment: 12 Pages Revtex, 2 eps figures
Modular differential equations for characters of RCFT
We discuss methods, based on the theory of vector-valued modular forms, to
determine all modular differential equations satisfied by the conformal
characters of RCFT; these modular equations are related to the null vector
relations of the operator algebra. Besides describing effective algorithmic
procedures, we illustrate our methods on an explicit example.Comment: 13 page
Regenerative approaches for V/UHTS feeder links: system analysis and on-board complexity reduction
The dramatically increasing demand for high data rates necessitates the proper dimensioning of the feeder links of very or ultra high throughput satellite (V/UHTS) systems. However, because most of the current solutions rely on transparent payloads, the deployment of a very large number of spatially separated ground stations is necessary to support the total system bandwidth by enabling a full reuse of the scarce available uplink bandwidth. This approach has a significant impact on the complexity and the costs of the ground segment infrastructure. Regenerative payloads could be considered to avoid this design bottleneck. By allowing demodulation and decoding on-board the satellite, the favourable link budget conditions of feeder links compared to the user links can be exploited. Using a spectral efficient transmission technique, the number of ground stations required to support a target sum throughput can be notably reduced. Meanwhile, regenerative solutions have until now barely been used in V/UHTS payloads due to their high on-board power consumption. As a consequence, candidate solutions are proposed in this work to overcome this limitation. A non-coherent modulation technique, known as Differential Amplitude Phase Shift Keying (DAPSK), is introduced to avoid on-board carrier synchronization. Moreover, polar codes are considered to minimize the power consumption of the channel decoder. A preliminary analysis of the expected on-board power consumption compared to that of a standard DVB-S2 approach is conducted using available results in the open literature. Link performance is also evaluated via numerical simulations
Absence of bound states for waveguides in 2D periodic structures
We study a Helmholtz-type spectral problem in a two-dimensional medium
consisting of a fully periodic background structure and a perturbation in form
of a line defect. The defect is aligned along one of the coordinate axes,
periodic in that direction (with the same periodicity as the background), and
bounded in the other direction. This setting models a so-called "soft-wall"
waveguide problem. We show that there are no bound states, i.e., the spectrum
of the operator under study contains no point spectrum.Comment: This is an updated version of our paper (in slightly different form
in Journal of Mathematical Physics). An anonymous reviewer kindly made us
aware that ref. 10 is not applicable in our situation. An application of the
theorem in ref. 10 would have proved the absence of singular continuous
spectrum also. Our result on the absence of point spectrum is not affected by
thi
Sensitivity and Specificity of Multiple Kato-Katz Thick Smears and a Circulating Cathodic Antigen Test for Schistosoma mansoni Diagnosis Pre- and Post-repeated-Praziquantel Treatment
Two Kato-Katz thick smears (Kato-Katzs) from a single stool are currently recommended for diagnosing Schistosoma mansoni infections to map areas for intervention. This ‘gold standard’ has low sensitivity at low infection intensities. The urine point-of-care circulating cathodic antigen test (POC-CCA) is potentially more sensitive but how accurately they detect S. mansoni after repeated praziquantel treatments, their suitability for measuring drug efficacy and their correlation with egg counts remain to be fully understood. We compared the accuracies of one to six Kato-Katzs and one POC-CCA for the diagnosis of S. mansoni in primary-school children who have received zero to ten praziquantel treatments. We determined the impact each diagnostic approach may have on monitoring and evaluation (M&E) and drug-efficacy findings
GPS-based fine-scale mapping surveys for schistosomiasis assessment: a practical introduction and documentation of field implementation
BACKGROUND: Fine-scale mapping of schistosomiasis to guide micro-targeting of interventions will gain importance in elimination settings, where the heterogeneity of transmission is often pronounced. Novel mobile applications offer new opportunities for disease mapping. We provide a practical introduction and documentation of the strengths and shortcomings of GPS-based household identification and participant recruitment using tablet-based applications for fine-scale schistosomiasis mapping at sub-district level in a remote area in Pemba, Tanzania. METHODS: A community-based household survey for urogenital schistosomiasis assessment was conducted from November 2020 until February 2021 in 20 small administrative areas in Pemba. For the survey, 1400 housing structures were prospectively and randomly selected from shapefile data. To identify pre-selected structures and collect survey-related data, field enumerators searched for the houses' geolocation using the mobile applications Open Data Kit (ODK) and MAPS.ME. The number of inhabited and uninhabited structures, the median distance between the pre-selected and recorded locations, and the dropout rates due to non-participation or non-submission of urine samples of sufficient volume for schistosomiasis testing was assessed. RESULTS: Among the 1400 randomly selected housing structures, 1396 (99.7%) were identified by the enumerators. The median distance between the pre-selected and recorded structures was 5.4 m. A total of 1098 (78.7%) were residential houses. Among them, 99 (9.0%) were dropped due to continuous absence of residents and 40 (3.6%) households refused to participate. In 797 (83.1%) among the 959 participating households, all eligible household members or all but one provided a urine sample of sufficient volume. CONCLUSIONS: The fine-scale mapping approach using a combination of ODK and an offline navigation application installed on tablet computers allows a very precise identification of housing structures. Dropouts due to non-residential housing structures, absence, non-participation and lack of urine need to be considered in survey designs. Our findings can guide the planning and implementation of future household-based mapping or longitudinal surveys and thus support micro-targeting and follow-up of interventions for schistosomiasis control and elimination in remote areas. Trial registration ISRCTN, ISCRCTN91431493. Registered 11 February 2020, https://www.isrctn.com/ISRCTN91431493
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