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    Amino acid profile of blood plasma of minks with Β«shadowΒ» gene polymorphism

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    The article presents the results of studies of the amino acid profile of mink blood plasma with KIT gene (receptor tyrosine kinase gene) polymorphism, which determines the formation of different coat colors (phenotype β€œshadow”) and underdevelopment of the genital organs in minks. It has been established that polymorphism of the shadow gene in the studied groups of minks is associated with multidirectional changes in the blood plasma content of some aliphatic and aromatic amino acids, as well as their main derivatives, which is due to the type of mutant allele present in the mink genotype, as well as their gender differences.Π’ ΡΡ‚Π°Ρ‚ΡŒΠ΅ прСдставлСны Ρ€Π΅Π·ΡƒΠ»ΡŒΡ‚Π°Ρ‚Ρ‹ исслСдований аминокислотного профиля ΠΏΠ»Π°Π·ΠΌΡ‹ ΠΊΡ€ΠΎΠ²ΠΈ Π½ΠΎΡ€ΠΎΠΊ ΠΏΡ€ΠΈ ΠΏΠΎΠ»ΠΈΠΌΠΎΡ€Ρ„ΠΈΠ·ΠΌΠ΅ Π³Π΅Π½Π° KIT (Ρ‚ΠΈΡ€ΠΎΠ·ΠΈΠ½ΠΊΠΈΠ½Π°Π·Π½ΠΎΠ³ΠΎ Ρ€Π΅Ρ†Π΅ΠΏΡ‚ΠΎΡ€Π°), Π΄Π΅Ρ‚Π΅Ρ€ΠΌΠΈΠ½ΠΈΡ€ΡƒΡŽΡ‰Π΅Π³ΠΎ Ρ„ΠΎΡ€ΠΌΠΈΡ€ΠΎΠ²Π°Π½ΠΈΠ΅ Ρ€Π°Π·Π»ΠΈΡ‡Π½ΠΎΠ³ΠΎ окраса ΡˆΠ΅Ρ€ΡΡ‚ΠΈ (Ρ„Π΅Π½ΠΎΡ‚ΠΈΠΏ Β«ΡˆΠ΅Π΄ΠΎΡƒΒ») ΠΈ Π½Π΅Π΄ΠΎΡ€Π°Π·Π²ΠΈΡ‚ΠΈΠ΅ Π΄Π΅Ρ‚ΠΎΡ€ΠΎΠ΄Π½Ρ‹Ρ… ΠΎΡ€Π³Π°Π½ΠΎΠ² Ρƒ Π½ΠΎΡ€ΠΎΠΊ. УстановлСно, Ρ‡Ρ‚ΠΎ ΠΏΠΎΠ»ΠΈΠΌΠΎΡ€Ρ„ΠΈΠ·ΠΌ Π³Π΅Π½Π° KIT Ρƒ исслСдуСмых Π³Ρ€ΡƒΠΏΠΏ Π½ΠΎΡ€ΠΎΠΊ ассоциирован с Ρ€Π°Π·Π½ΠΎΠ½Π°ΠΏΡ€Π°Π²Π»Π΅Π½Π½Ρ‹ΠΌ ΠΈΠ·ΠΌΠ΅Π½Π΅Π½ΠΈΠ΅ΠΌ содСрТания Π² ΠΏΠ»Π°Π·ΠΌΠ΅ ΠΊΡ€ΠΎΠ²ΠΈ ряда алифатичСских ΠΈ ароматичСских аминокислот, Π° Ρ‚Π°ΠΊΠΆΠ΅ ΠΈΡ… основных ΠΌΠ΅Ρ‚Π°Π±ΠΎΠ»ΠΈΡ‚ΠΎΠ², Ρ‡Ρ‚ΠΎ обусловлСно Ρ‚ΠΈΠΏΠΎΠΌ ΠΌΡƒΡ‚Π°Π½Ρ‚Π½ΠΎΠ³ΠΎ аллСля, ΠΏΡ€ΠΈΡΡƒΡ‚ΡΡ‚Π²ΡƒΡŽΡ‰ΠΈΠΌ Π² Π³Π΅Π½ΠΎΡ‚ΠΈΠΏΠ΅ исслСдуСмых Π½ΠΎΡ€ΠΎΠΊ, Π° Ρ‚Π°ΠΊΠΆΠ΅ ΠΈΡ… ΠΏΠΎΠ»ΠΎΠ²Ρ‹ΠΌΠΈ различиями
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