85 research outputs found

    Learning from Sustainability-Oriented Innovation

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    This chapter argues that insights from the realm of sustainability-oriented innovation can provide useful answers to the question of why Small and Medium-Sized Enterprises (SMEs) would (or should) become interested in implementing responsible innovation practices. It is based on the assumption that “responsible innovation” and “sustainability-oriented innovation” are different approaches aimed at orienting innovation towards increased positive impacts on social and natural environments. Motivations and influences for pursuing sustainability-oriented inno-vation have been studied in the past, and can provide insights into reasons for pursu-ing the implementation of responsible innovation practices

    Which Green Matters for Whom? Greening and Firm Performance across Age and Size Distribution of Firms.

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    A growing body of literature links firm performance with sustainability efforts.We contribute to this literature by developing a novel framework for contextualising greening through the lens of tangibility and visibility of greening activities and examine the impact of different types of greening on firm performance along the age and size distribution of firms. The empirical results based on a large-scale database suggest that rewards to different types of greening differ across age and size distributions

    Old World Arenaviruses Enter the Host Cell via the Multivesicular Body and Depend on the Endosomal Sorting Complex Required for Transport

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    The highly pathogenic Old World arenavirus Lassa virus (LASV) and the prototypic arenavirus lymphocytic choriomeningitis virus (LCMV) use α-dystroglycan as a cellular receptor and enter the host cell by an unusual endocytotic pathway independent of clathrin, caveolin, dynamin, and actin. Upon internalization, the viruses are delivered to acidified endosomes in a Rab5-independent manner bypassing classical routes of incoming vesicular trafficking. Here we sought to identify cellular factors involved in the unusual and largely unknown entry pathway of LASV and LCMV. Cell entry of LASV and LCMV required microtubular transport to late endosomes, consistent with the low fusion pH of the viral envelope glycoproteins. Productive infection with recombinant LCMV expressing LASV envelope glycoprotein (rLCMV-LASVGP) and LCMV depended on phosphatidyl inositol 3-kinase (PI3K) as well as lysobisphosphatidic acid (LBPA), an unusual phospholipid that is involved in the formation of intraluminal vesicles (ILV) of the multivesicular body (MVB) of the late endosome. We provide evidence for a role of the endosomal sorting complex required for transport (ESCRT) in LASV and LCMV cell entry, in particular the ESCRT components Hrs, Tsg101, Vps22, and Vps24, as well as the ESCRT-associated ATPase Vps4 involved in fission of ILV. Productive infection with rLCMV-LASVGP and LCMV also critically depended on the ESCRT-associated protein Alix, which is implicated in membrane dynamics of the MVB/late endosomes. Our study identifies crucial cellular factors implicated in Old World arenavirus cell entry and indicates that LASV and LCMV invade the host cell passing via the MVB/late endosome. Our data further suggest that the virus-receptor complexes undergo sorting into ILV of the MVB mediated by the ESCRT, possibly using a pathway that may be linked to the cellular trafficking and degradation of the cellular receptor

    Ultrafast laser micro-nano structuring of transparent materials with high aspect ratio

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    Ultrafast lasers are ideal tools to process transparent materials because they spatially confine the deposition of laser energy within the material's bulk via nonlinear photoionization processes. Nonlinear propagation and filamentation were initially regarded as deleterious effects. But in the last decade, they turned out to be benefits to control energy deposition over long distances. These effects create very high aspect ratio structures which have found a number of important applications, particularly for glass separation with non-ablative techniques. This chapter reviews the developments of in-volume ultrafast laser processing of transparent materials. We discuss the basic physics of the processes, characterization means, filamentation of Gaussian and Bessel beams and provide an overview of present applications

    WZ59_Mont2_Poem1 (2021)

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    Nowness N O W when thinking, when making, when experiencing, when remembering. Now is gone, comes, goes, multiplies, with no beginning, and no end. The present of the pasts, the present of the presents, the present of the futures, Past times, present times, future times, What was time, what is time, what will time be? When was now, when is now, when will now be? Now was never, is never, will never be. N O W forever, in infinity

    Research outputs for the PhD by Published Work “Potentials and limitations of language in observing and interpreting art”

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    Research outputs for the PhD by Published Work “Potentials and limitations of language in observing and interpreting art” https://westminsterresearch.westminster.ac.uk/item/w2y7q/potentials-and-limitations-of-language-in-observing-and-interpreting-ar

    Freedom to create

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    I wrote this compendium for you, who wants to independently learn and practice anything related to art, design, and craft-making. Essentially, I offer you guidance to handle your creative freedom by engaging your thinking with affirmative prompts, followed by questions. Your answers could become your tentative roadmap in your creative journey, with the option to change directions at any time during your travel. While compiling my thoughts, I emphasised the idea of putting you in the driver’s seat to help you set off and pursue your very own journey to create. Enjoy and celebrate your process and results, always

    Insights into an Artistic Practice through Self-Reflection

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    The paper discusses insights from a post-disciplinary artist who reflects on his artistic practice. This case study is written from an autoethnographical perspective, in a narrative-evocative voice, contextualised with Moon’s strategies of reflective learning and the Socratic method. Adapted on Moon’s suggestions and based on the Socratic discourse of self-examination, semi-structured questions for the self-reflection have been prompted whilst reading texts of Bergson’s process philosophy. These questions have then been scrutinised if and how they are relevant to the artist’s practice. The artist also reflected on his emotions during the reflective writing process and in retrospective thereof which further developed the writing process and content selection of the self-reflection. The general aim of the subjective reflection was to verbalise the complex layers of meanings that are inherent in his artistic processes. The author anticipates that the self-reflection could serve as a case study for students in mainly, but not exclusively, tertiary art education. Ideally, the research could be a guidance, or inspiration, for students to find their own sources for reflection such as writings, artworks or exhibitions, which could trigger questions about their individual artistic processes and outcomes. Based on the artist’s experiences, in the context of his on-going doctoral research, such self-reflections could enhance other students’ and artists’ metacognitions as competencies to better communicate their own artistic practices
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