ROLE AND PURPOSE OF NSICOP IN CANADIAN NATIONAL SECURITY

On November 17, 2023, Lisa-Marie Inman, Executive Director, Secretariat, and Jennifer Kleniewski, Senior Review Analyst and Team Lead, at the National Security and Intelligence Committee of Parliamentarians (NSICOP), presented the Role and Purpose of NSICOP in Canadian National Security for this year’s West Coast Security Conference. The presentation was followed by a question-and-answer period with questions from the audience and CASIS Vancouver executives. The key points discussed were the committee's mandate to provide increased parliamentary oversight over the activities of Canadian intelligence agencies, the content and release of its annual and special reports, and the nonpartisan and representative nature of the committee's composition.   Received: 01-04-2024 Revised: 01-26-202

Modulation of the cell membrane expression of the kininogens regulates the rate of bradykinin delivery to cells

The kininogens were first recognized as the parent molecules for bradykinin. Their relative physiologic importance in plasma hemostasis and fibrinolysis and tissue cysteine protease inhibition has not been clarifed. Recent studies on the structure and function of the plasma kininogens, their interaction with cells of the intravascular compartment, and clinical investigations on contact system activation have refocused the physiologic importance of these proteins to kinin delivery for the maintance of vasodilatory tone. Kininogen expression on platelets slows the rate of kinin liberation, and kinins upregulate kininogen expression on endothelial cells. Regulation of kinin delivery by influencing kininogen expression may provide for new agents to manipulate blood pressure.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/30063/1/0000433.pd

Space, the city and social theory

As the author states in her introduction, Space, the City and Social Theory is not intended to be read as an overview of either urban sociology or urban studies, but is instead concerned with providing an account of how social theory has encountered and illuminated the city. It takes its cue from two main bodies of literature. The first is the Chicago School of urban sociology, especially the work of Robert Park and Louis Wirth, while the second is European social theory and, in particular, the contributions of Simmel, Benjamin, Lefebvre, Michel de Certeau and Roland Barthes. As can be seen from this list of authors, the book has a tendency to focus upon small-scale social interactions and how the city is subjectively experienced, for example via the urban archetype of the flaneur as discussed at length in chapter 6. The book contains seven substantive chapters beginning in chapter 1 with the quintessential urban dialectic of community and solitude. Chapter 2 concerns itself with socio-spatial divisions and differences, focusing on such well-worn themes as the ghetto and social disorganization, but also including a useful discussion of social capital. The politics of urban space is examined in chapter 3. This is done, first, via a discussion of urban social movements, largely based upon a reading of Castells and Lefebvre, and, second, via an examination of the 'micro-politics of urban life', focusing upon the street as a site of social encounters and contestation. Chapter 4 deals with gentrification, whilst chapter 5 considers the embodied nature of the city in relation to gender and sexuality, themes which tend to be marginalized in traditional urban textbooks. Chapter 5 includes topics such as prostitution, lesbian and gay geographies, and women's dual sense of urban freedom and fear of violence. Chapter 6 provides a sustained discussion of the subjective experience of the city via an analysis of Simmel, Benjamin and de Certeau. The latter reappears in chapter 7, which examines the ways that the spatial order of the city can be disrupted. This is seen with reference to Foucault's concept of heterotopia, Barthes' semiology of the city and de Certeau's notion of spatial tactics. The latter is very nicely illustrated by a discussion of urban graffiti and skateboarding