ROC plot of BI-RADS ratings against the reference standard.

<p>At a cut-off of >BI-RADS 3, the sensitivity and specificity were 96.4% and 92.4%, respectively. In addition, at a cut-off of >BI-RADS 2 the sensitivity and specificity were 100% and 70.3%, respectively.</p

Summary of the results of this study: MRI findings are stratified by conventional imaging findings, clinical presentation, and ACR breast composition.

<p>Resulting cancer prevalence, sensitivity, specificity, positive predictive value (PPV), and negative predictive value (NPV) considering BI-RADS 4 and 5 as positive and BI-RADS 1–3 as negative MRI results.</p

3 Tesla breast MR imaging as a problem-solving tool: Diagnostic performance and incidental lesions - Fig 2

<p>A 52-year-old patient referred for problem-solving due to newly diagnosed architectural distortion in the left breast (A; white circles on mammography images). 3T contrast-enhanced MR imaging (B; top: T2w image, middle: early contrast-enhanced image, bottom: late contrast-enhanced image) shows the architectural distortion (white circle) demonstrating only mild background enhancement. The lesion was classified as BI-RADS 2, definitely benign. Follow-up of two years did not reveal malignancy.</p

Prevention of epidural scarring after microdiscectomy: a randomized clinical trial comparing gel and expanded polytetrafluoroethylene membrane

A randomized clinical trial compared two materials used to prevent epidural scarring after microdiscectomy. To determine whether ADCON®-L Gel (ALG) or Preclude Spinal Membrane® (PSM) was more effective in preventing scarring, reducing pain, and improving quality of life postoperatively. Postdiscectomy syndrome may result from epidural scarring. Various materials have been used in attempts to prevent this problem, but none have provided optimal results. Previous laboratory and clinical studies have found ALG and PSM to be effective, but none compared the two materials. Thirty-one patients undergoing primary microdiscectomy were randomly assigned to receive either ALG or PSM. Postoperatively, patients were evaluated by magnetic resonance imaging (MRI), with contrast, for volume and rostral–caudal extent of scar tissue and nerve root involvement. Back and leg pain and quality of life were assessed by neurologic examinations and standardized patient surveys. Findings at any reoperations were recorded. Results in the PSM (n = 18) and ALG (n = 13) groups were compared statistically. No operative or postoperative complications occurred. Two patients in each group required reoperation. MRI at 6 months showed no, mild or mild-moderate scarring in most patients, with no significant differences between the ALG and PSM groups in scar volume and extent or nerve root involvement. Neurologic examinations and patient surveys showed substantial reductions in pain over time in both groups but no significant differences between groups. PSM was easy to see and remove at reoperation. PSM and ALG are equally effective in preventing epidural scarring associated with postdiscectomy syndrome