1,510 research outputs found
Алгоритм построения прогнозируемой площади пожара в тактической модели
The miniaturization of components in the field of life science, consumer electronics and micro-electro-mechanical systems (MEMS) is becoming a part of our everyday life. As the manufacturing of these components demands in many cases the machining by micromilling with cutting tools down to 100 µm diameter, highly dynamic machine tools are needed to machine the more and more complex freeform surfaces at optimal process parameters. The paper describes the development of a highly dynamic milling machine which is equipped with linear direct drives in all axes with integrated impulse decoupling units to allow high dynamics and especially high jerks at low impact on the machine structure. Additionally the development of a metrology frame is detailed which can be used to characterize the dyna mic tool path of machine tools to optimize its dynamic setup and to increase the work piece precision at minimized machining time
Photoluminescence and photoluminescence excitation studies of lateral size effects in Zn_{1-x}Mn_xSe/ZnSe quantum disc samples of different radii
Quantum disc structures (with diameters of 200 nm and 100 nm) were prepared
from a Zn_{0.72}Mn_{0.28}Se/ZnSe single quantum well structure by electron beam
lithography followed by an etching procedure which combined dry and wet etching
techniques. The quantum disc structures and the parent structure were studied
by photoluminescence and photoluminescence excitation spectroscopy. For the
light-hole excitons in the quantum well region, shifts of the energy positions
are observed following fabrication of the discs, confirming that strain
relaxation occurs in the pillars. The light-hole exciton lines also sharpen
following disc fabrication: this is due to an interplay between strain effects
(related to dislocations) and the lateral size of the discs. A further
consequence of the small lateral sizes of the discs is that the intensity of
the donor-bound exciton emission from the disc is found to decrease with the
disc radius. These size-related effects occur before the disc radius is reduced
to dimensions necessary for lateral quantum confinement to occur but will
remain important when the discs are made small enough to be considered as
quantum dots.Comment: LaTeX2e, 13 pages, 6 figures (epsfig
Kinetic-controlled hydrodynamics for multilane traffic models
We study the application of a recently introduced hierarchical description of
traffic flow control by driver-assist vehicles to include lane changing
dynamics. Lane-dependent feedback control strategies are implemented at the
level of vehicles and the aggregate trends are studied by means of
Boltzmann-type equations determining three different hydrodynamics based on the
lane switching frequency. System of first order macroscopic equations
describing the evolution of densities along the lanes are then consistently
determined through a suitable closured strategy. Numerical examples are then
presented to illustrate the features of the proposed hierarchical approach
Crop water stress index for beans obtained from temperature difference between canopy and air.
Canopy temperature (Tc), besides serving as a parameter to estimate crop evapotranspiration (ETc), can also be used to define water stress indexes that have the advantage to serve as a reference for the rational scheduling for irrigation for a crop. One of these indexes, which has been well disseminated, is the crop water stress index (CWSI), based on the ratio between crop resistance and aerodynamic resistance (rc/ra), whose value can be estimated by the difference between the cropy canopy and the air (Tc - Ta). A study was carried out with the objective of obtaining CWSI values for beans (Phaseolus vulgaris L.), under field conditions, in which the crop was under different irrigation scheduling; 2, 4, 8, 12 and 16 day intervals. The experiment was conducted at Sete Lagoas, Minas Gerais State, Brazil, in the period from July through October, 1995. Tc values were measured by means of infrared thermometry at two times of the day; between 10:00 and 11:00 am, and between 01:00 and 02:00 p.m. The obtained results pointed to a limit of 0,15 as a reference for the beginning of water stress to occur, which is consistent with other work and other index obtained under similar conditions
Estimativa da evapotranspiração máxima do feijoeiro (Phaseolus vulgaris L.) em função do índice de área foliar e da evaporação da água do tanque classe A.
Um metodo simples que tem sido amplamente usado na obtencao da evapotranspiracao da cultura (ET) e o padronizado pela FAO. Esse se baseia em medir a evaporacao de agua do tanque Classe A (ECA) e multiplicar por coeficientes ( do tanque e da cultura) que geracao a ET. No entanto, a estimativa dos referidos coeficientes (K, e K,) nem sempre retrata de forma satisfatoria as condicoes da cultura. Procurando-se vencer essa dificuldade, tornando-se desnecessario o uso de tais coeficientes, foi objetivo deste trabalho comporvar a boa concordancia entre a ET, calculada pelo metodo de Penman-Monteith, e o indice de area foliar (IAF) e a ECA e entre a ET, unicamente com o IAF, atraves da analise de regressao linear multipla, para o feijoeiro. A melhor relacao encontrada foi a que considerou o fator biologico (IAF) conjuntamente com o ambiental (ECA), isto e, ET = -1.304 + 0,8368.iaf + 0,5537.ECA (r2 = 0,854), comprovando a metodologia como de boa eficiencia para predizer a ET
FATP4 missense and nonsense mutations cause similar features in Ichthyosis Prematurity Syndrome
<p>Abstract</p> <p>Background</p> <p>Ichthyosis Prematurity Syndrome (IPS) is an autosomal recessive disorder characterized by premature birth, non-scaly ichthyosis and atopic manifestations. The disease was recently shown to be caused by mutations in the gene encoding the fatty acid transport protein 4 (FATP4) and a specific reduction in the incorporation of very long chain fatty acids (VLCFA) into cellular lipids.</p> <p>Findings</p> <p>We screened probands from five families segregating IPS for mutations in the <it>FATP4 </it>gene. Four probands were compound heterozygous for four different mutations of which three are novel. Four patients were heterozygous and one patient homozygous for the previously reported non-sense mutation p.C168X (c.504c > a). All patients had clinical characteristics of IPS and a similar clinical course.</p> <p>Conclusions</p> <p>Missense mutations and non-sense mutations in <it>FATP4 </it>are associated with similar clinical features suggesting that missense mutations have a severe impact on FATP4 function. The results broaden the mutational spectrum in <it>FATP4 </it>associated with IPS for molecular diagnosis of and further functional analysis of FATP4.</p
Electron Impact Ionization Close to the Threshold: Classical Calculations
In this paper we present Classical Trajectory Monte Carlo (CTMC) calculations
for single and multiple electron ionization of Argon atoms and ions in the
threshold region. We are able to recover the Wannier exponents a for the
power-law behavior of the cross section s versus excess energy: the exact value
of the exponent as well as the existence of its saturation for multiple
ionization appear to be related to how the total binding energy is shared
between target electrons.Comment: 9 pages. To be published in Journal of Physics
Identification of a novel type of spacer element required for imprinting in fission yeast
Asymmetrical segregation of differentiated sister chromatids is thought to be important for cellular differentiation in higher
eukaryotes. Similarly, in fission yeast, cellular differentiation involves the asymmetrical segregation of a chromosomal
imprint. This imprint has been shown to consist of two ribonucleotides that are incorporated into the DNA during laggingstrand
synthesis in response to a replication pause, but the underlying mechanism remains unknown. Here we present key
novel discoveries important for unravelling this process. Our data show that cis-acting sequences within the mat1 cassette
mediate pausing of replication forks at the proximity of the imprinting site, and the results suggest that this pause dictates
specific priming at the position of imprinting in a sequence-independent manner. Also, we identify a novel type of cis-acting
spacer region important for the imprinting process that affects where subsequent primers are put down after the
replication fork is released from the pause. Thus, our data suggest that the imprint is formed by ligation of a not-fullyprocessed
Okazaki fragment to the subsequent fragment. The presented work addresses how differentiated sister
chromatids are established during DNA replication through the involvement of replication barriers
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