The Grizzly, March 22, 1985

WVOU to Broadcast to Wismer • U.C. Receives $32,000 in Grants • Letter: Thoughtless Student Hurts Feelings • New Faces, New Places • Woman\u27s Club Events • Independent Eye Stages Macbeth • Meistersingers to Present Spring Program • Stevenson Resigns as Golf Coachhttps://digitalcommons.ursinus.edu/grizzlynews/1136/thumbnail.jp

Replacing the Transfusion of 1-2 Units of Blood with Plasma Expanders that Increase Oxygen Delivery Capacity: Evidence from Experimental Studies.

At least a third of the blood supply in the world is used to transfuse 1-2 units of packed red blood cells for each intervention and most clinical trials of blood substitutes have been carried out at this level of oxygen carrying capacity (OCC) restoration. However, the increase of oxygenation achieved is marginal or none at all for molecular hemoglobin (Hb) products, due to their lingering vasoactivity. This has provided the impetus for the development of "oxygen therapeutics" using Hb-based molecules that have high oxygen affinity and target delivery of oxygen to anoxic areas. However it is still unclear how these oxygen carriers counteract or mitigate the functional effects of anemia due to obstruction, vasoconstriction and under-perfusion. Indeed, they are administered as a low dosage/low volume therapeutic Hb (subsequently further diluted in the circulatory pool) and hence induce extremely small OCC changes. Hyperviscous plasma expanders provide an alternative to oxygen therapeutics by increasing the oxygen delivery capacity (ODC); in anemia they induce supra-perfusion and increase tissue perfusion (flow) by as much as 50%. Polyethylene glycol conjugate albumin (PEG-Alb) accomplishes this by enhancing the shear thinning behavior of diluted blood, which increases microvascular endothelial shear stress, causes vasodilation and lowering peripheral vascular resistance thus facilitating cardiac function. Induction of supra-perfusion takes advantage of the fact that ODC is the product of OCC and blood flow and hence can be maintained by increasing either or both. Animal studies suggest that this approach may save a considerable fraction of the blood supply. It has an additional benefit of enhancing tissue clearance of toxic metabolites

E-Predict: a computational strategy for species identification based on observed DNA microarray hybridization patterns

DNA microarrays may be used to identify microbial species present in environmental and clinical samples. However, automated tools for reliable species identification based on observed microarray hybridization patterns are lacking. We present an algorithm, E-Predict, for microarray-based species identification. E-Predict compares observed hybridization patterns with theoretical energy profiles representing different species. We demonstrate the application of the algorithm to viral detection in a set of clinical samples and discuss its relevance to other metagenomic applications

The Grizzly, November 30, 1984

Board Approves $825 Increase in Annual Tuition, Room and Board • Glick Summons Students: Wood Responds to Roving Reporter • Shorts: Messiah; Spring Jobs; Ice Fishing • Hoop Team Upsets West Chester in Opener • Booters Finish Great Season • Mers and Vers Attend Bloomsburg Invitational • Whatley Plans to Expand Intramurals • Co-ed Volleyball Ends • Fencing in First Competition • Scenes From the Soccer Seasonhttps://digitalcommons.ursinus.edu/grizzlynews/1129/thumbnail.jp

The Grizzly, February 22, 1985

Auto Blaze Cuts Phone Service • New Forensics Society Competing Successfully • All is Well With All\u27s Well Cast • Career Program Scheduled • Students Invited to Presidential Symposium • Pi Gamma Mu Seeks New Members • UC Selected for Ed Project • Bloodmobile Here in March • Nutrition Forum Tuesday • Bears Beat Swarthmore to Finish Season • Baseball Trains for Season and Florida Trip • Carr Puts Teams in Drive • Wellness Week Aimed at Promoting Overall Health • Night on Ice Scheduledhttps://digitalcommons.ursinus.edu/grizzlynews/1134/thumbnail.jp

The Grizzly, February 15, 1985

USGA Reschedules Election • Japanese Studies Prof. Returns to U.C. • UC Retention Rate Above National Average • Without Reform, Second Election Doomed to Failure • U.C. Contributes to Local Secondary Education: Need for Tutors May Grow • College Students Have Trouble Managing Money, Survey Shows • Campus Life Surveys Possible Displacements • Grapplers Keep Winning: Wiehler Notches 14-second Fall • Senior Matmen Get Last Shot at MAC Title • Ververeli Operates on the Mats for Now • Mers Dunk Dips • Mermaids Win Three, Lose One • UC Grad Writes Book • B-ball Drops Two • Lady Hoopsters\u27 Losing Ways Continuehttps://digitalcommons.ursinus.edu/grizzlynews/1133/thumbnail.jp

The Grizzly, April 12, 1985

Construction of Three Athletic Fields is Underway • Dumb Jock Image Unfair Stereotype, Study Says • Campus Shows Concern for African Hunger Problem • Concert Review: Pink Floyd\u27s Leader Provides Powerful Performance • Bear Batters Face Tough Times • Talent Show Moments • Girl\u27s Lacrosse Wins Five, Drops Two • Men\u27s Track Places First, Second in Two Meets • Intramural Basketball Season Endshttps://digitalcommons.ursinus.edu/grizzlynews/1139/thumbnail.jp

The Grizzly, March 1, 1985

Students Recapture Bear • Road Crews Close Route 29 • Future of Greeks Depends Upon Pledging • Letters: Softball Team Wants Recognition; Inconsiderate Students Annoy Peers; Students Must Grow Up • Springsteen Wins His First Grammy • A Passage to India Deserves a Ten Rating • Van Morrison Comes Back • Profile: Local Man Leads Different Sort of Life • Campus Priest Popular with Students • Men\u27s Track Goes to MAC\u27s • Choir, Orchestra to Perform Handel • Scenes From the Show • Nobel Prize Winner to Speak Tuesday • Fraternity Pledging Underwayhttps://digitalcommons.ursinus.edu/grizzlynews/1135/thumbnail.jp

The Grizzly, March 29, 1985

St. Joe\u27s to Offer MBA Program on Ursinus Campus • New Poli Sci Professor Hired • Main St. Renovations Scheduled • Co-ed Housing to Start Next Year in Reimert Complex • Community Opposes Vigilantes • Dining Committee Presents New Recipe Program • Car Stairs, S.P.E.C.T.E.R. Undefeated in College Bowl • Student Relates German Experience • Defending Champs Open Lax Season with Win • Baseball Squad Off to Sluggish Start • New Coach Readies Golfers for Tough Week • Senior Diver Finishes 19th in NCAA Championshipshttps://digitalcommons.ursinus.edu/grizzlynews/1137/thumbnail.jp