Examples of the electropherograms for the selected markers, ordered to their chromosomal position.

<p>On the Y-axis, the peak intensity is given. On the X-axis, the fragment size is given in basepairs. On the left side, results from normal tissue are shown. Note that these markers have few or no stutter peaks and a fairly constant ratio (close to 1) between the heights of the two alleles. On the right side, results from representative tumor samples with LOH are shown.</p

Results of the microsatellite analysis of pre-TUR urine samples.

<p><a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0043345#s3" target="_blank">Results</a> of the microsatellite analysis of pre-TUR urine samples.</p

Overview of the variation between allele ratios for different markers.

<p>On the Y-axis, the ratio between the two alleles is given. On the X-axis, the different microsatellite markers are listed. A. The boxplots show that some previously used markers have a large variation in their allele ratio based on an analysis of blood DNA samples from 50 individuals. B. Behavior of the 12 selected markers, indicating they have very little variation in their allele ratio when tested on normal blood and urine from healthy individuals. C. In primary tumor DNA the allele ratio is much more variable due to LOH/AI.</p

Microsatellite markers selected for this study.

<p>Het: the expected heterozygosity (%) according to the CEPH database (<a href="http://www.cephb.fr/en/cephdb/browser.php" target="_blank">http://www.cephb.fr/en/cephdb/browser.php</a>). F/R: forward or reverse primer.</p

Flow chart of the study.

<p>Flow chart of the study.</p