Surgical management of blunt pancreatic trauma: A modus operandi or individualized therapy?

The overall rate of blunt pancreatic trauma observed in level one trauma centers is rather low compared to other injuries, with a reported prevalence of 0.4 per 100,000 hospital admissions. The situation may be further complicated by the presence of associated major visceral injuries in these patients. A number of previous reports indicate that blunt pancreatic trauma carries high morbidity and mortality rates, especially when diagnosis is delayed or inappropriate surgery is attempted. Many mandate prompt surgical explorations for organ-specific diagnosis on CT; however other literature and upcoming studies prove otherwise. Over the years, several technologic advances have increased the sophistication of non-operative management. In our case, a period of careful observation followed by surgical intervention did not adversely effect the outcome. The period of observation resulted in stabilization of other solid organ injuries with focus on pancreas during surgical exploration

Perceived Stress and Religious Coping among Pakistani-Origin Emerging Muslim Adults Living in Pakistan and the United States: A Cross-Cultural View

This study explored the relationship between Perceived Stress and Religious Coping levels among Muslim emerging adults of Pakistani origin living in Pakistan and Muslim emerging adults of Pakistani origin living in the United States (US). Participants (Pakistani Origin Muslims Living in Pakistan, n= 103; and Pakistani Origin Muslims Living in the US, n=50) were between 18-25 years old. The Perceived Stress Scale (PSS-10) and Brief R-Cope scale were administered using an online format. Results indicated that negative religious coping strategies were associated with higher perceived stress in both groups while positive religious coping strategies showed a weaker association with lower perceived stress levels, and this finding appeared only in the US sample. Marital status was also an important predictor of perceived stress. These findings demonstrate that Muslim emerging adults, irrespective of culture, show moderately similar patterns in their perception of stress and their utilization of religious coping strategies

What Determines the Domestic Prices of Agricultural Commodities in Pakistan?

Rarely a month passes-by in Pakistan without complains on the state of basic commodity markets, be it wheat or sugar, cotton or rice. Prices are too high for the consumers, or too low for the farmers; and often the government is asked to intervene, buying for or selling from stocks, prohibiting export or import, increasing or reducing import duties, introducing/withdrawing export taxes, or taking other measures to protect the consumer or producer. It is as if domestic prices can have a life on their own, with the government asked to guarantee “fair” prices for everbody. The resulting on-and-off policy intervention by the government is likely to have had a deleterious effect on the development of the domestic and international trade for these commodities. This is because of the uncertainty so generated, with the private traders always facing the risk of a regime change at a time when import or export contracts have already been signed. As a result too, the role of the state-owned Trading Corporation of Pakistan self-perpetuates, even if the government would like to see it minimised, as it is always being asked to intervene because of the private sector’s “failings”

Self-Similar Graphs

For any graph $G$ on $n$ vertices and for any {\em symmetric} subgraph $J$ of $K_{n,n}$, we construct an infinite sequence of graphs based on the pair $(G,J)$. The First graph in the sequence is $G$, then at each stage replacing every vertex of the previous graph by a copy of $G$ and every edge of the previous graph by a copy of $J$ the new graph is constructed. We call these graphs {\em self-similar} graphs. We are interested in delineating those pairs $(G,J)$ for which the chromatic numbers of the graphs in the sequence are bounded. Here we have some partial results. When $G$ is a complete graph and $J$ is a special matching we show that every graph in the resulting sequence is an {\em expander} graph.Comment: 13 pages, 1 tabl

Modeling of Dielectric Resonator Antennas using Numerical Methods Applied to EPR

This chapter presents an inclusive analysis of notable techniques carried out on modeling of dielectric resonator (DR)-antenna using numerical methods in last more than two decades. Dielectric resonator antenna (DRA) has created its individual existence in antenna engineering because of its captivating characteristics like; small size, low loss, high efficiency, wide bandwidth, three-dimensional design flexibility as compared to conventional antennas, etc. The DR antennas are being widely modeled using numerical methods nowadays. The triple-folded intention of this chapter is to: (1) give an overview on DRA modeling using single and hybrid numerical methods, (2) give a compressive review of notable numerical modeling researches carried out on DRAs and (3) give some favorable future concentration for the antenna researchers in order to apply the numerical methods on some innovative geometries of DRAs

The Journey of Digital Library Establishment in Pakistan: A Systematic Literature Review

This study examined the published literature on digital library resources and the users’ experiences (i.e. satisfaction level, motivating factors, and major challenges) with these resources in Pakistan. Several e-databases were consulted including Research Gate’, ScienceDirect, Web of Science, and Google Scholar to retrieve relevant literature. The study adopted a systematic literature review approach followed by PRISMA guidelines. Out of 323 articles, a total of 22 relevant studies were included based on pre-defined inclusion and exclusion criteria. The findings of this study reveal that most of the end-users are satisfied with the digital library resources, and they consulted these resources for academic and research endeavors. The authenticity and accuracy of the DLRs were the main motivating factors in the effective use of DLRs. Furthermore, this study consolidated several factors faced by end-users while using DLRs. The results of this study could help the policymakers, HEC authority, LIS professionals to further improve access to DLRs and resolve the problems facing end-users in the country. Moreover, the findings of this study will help the university administration and library authority to plan the subscription of resources keeping in view the associated barriers

TOPICAL ANTI-PSORIATIC NANOPARTICULATE DRUG DELIVERY SYSTEM

Objective: Development of effective drug delivery in the treatment of psoriasis is the major challenge for its successful management. To develop and assess the potential of Nanostructured Lipid Carriers (NLCs) enriched with the powdered leaves extracts of Azadirachta indica (AE), Lawsonia inermis (LE) and fruit extract of Mallotus philippensis (ME) in the management of psoriasis. Methods: Drug loaded NLCs were prepared via hot homogenization technique by adopting 23 factorial design with factors X1 as the concentration of lipids, X2 concentration of surfactants and X3 being the number of homogenization cycle. The responses Y1 and Y2 were particle size and zeta potential. The optimized batch was obtained from Surface response plot and was evaluated for zeta potential, % entrapment efficiency, % drug loading, Scanning Electron Microscopy(SEM), % in vitro diffusion of drugs from the NLCs, anti-lipid peroxidation and nitric oxide scavenging activities, cytotoxicity on HaCat cell lines, Mouse Tail and Rat ultraviolet ray B photodermatitis models for Psoriasis. Results: The optimized batch of NLCs was found within the nanosized range with a relatively low polydispersity index and zeta potential of-20mV. The %EE for an optimized batch of NLCs was found to be 98.97±0.83%, 96.99±0.56% and 99.25±0.55% and the %DL of 21.84±0.15%, 8.55±045%, and 87.91±0.38% respectively for AE, LE and ME. The SEM images showed the spherical vesicular structures of drugs loaded NLCs. The in-vitro diffusion of drugs from the NLCs followed initial burst release thereafter sustained release for 24 h. The AE, LE and ME loaded NLCs proved to possess anti-lipid peroxidation and nitric oxide scavenging activities, cytotoxicity on HaCat cell lines, DNA fragmentation on HaCat cell lines which are biomarkers in the pathogenesis of psoriasis. The results of Mouse Tail and Rat ultraviolet ray B photodermatitis models for Psoriasis supported the anti-psoriatic potential of AE, LE and ME loaded NLCs. Conclusion: AE, LE and ME loaded NLCs can be used for prolonged topical delivery to the psoriatic skin for an effective treatment