John Wheeler, relativity, and quantum information

In spring 1952, as John Wheeler neared the end of design work for the first thermonuclear explosion, he plotted a radical change of research direction: from particles and atomic nuclei to general relativity

A Case Report: Diabetic Amputee

Background and Purpose: The purpose of this case study is to present the reader with a detailed description of the physical therapy provided for a diabetic lower extremity amputee. As the number of amputations across America steadily increase, there is an elevated importance of understanding the prevalence, causes, and reasons for amputations and which interventions are most effective in increasing a patient\u27s quality of life. Case Description: The patient is a 77 year old male with significant past medical history of type I diabetes mellitus, hypertension, and osteoarthritis. This patient has significant gross muscle weakness in both his upper and lower extremities. Following his amputation proper prosthetic fitting could not be completed secondary to his significant weakness. Physical therapy intervention focused on functional exercises to help this patient return home safely with complete independence. Discussion: Most amputees receive a prosthetic shortly after surgery; however, a small amount of new amputees do not have the strength, stamina, and independence to begin functioning with a prosthetic immediately after surgery. Further research needs to be conducted focusing on which interventions and treatment strategies are most effective for patients that are not able to be fit with a prosthetic following surgery

The introduction of virtual reality in forensic mental healthcare:n interview study on the first impressions of patients and healthcare providers regarding VR in treatment

Background: Recognizing the potential of Virtual Reality (VR) as a powerful technology to support behavior change, the careful introduction of this technology into treatment settings is essential. This is especially important in vulnerable populations like forensic psychiatric patients. This study aims to gain insight from the impressions of both patients and healthcare providers concerning the integration of VR in practice. The study aims to contribute valuable information that guides the introduction of VR technology, ensuring its optimal use in the complex context of forensic mental healthcare.Methods: Semi-structured interviews were conducted with healthcare providers (n = 10) working at forensic outpatient clinics and forensic psychiatric patients (n = 8). All participants experienced VR before the interview. Inductive thematic analysis was employed for analyzing the interview data.Results: Patients valued the unique opportunity to simulate personal experiences in VR scenarios and reflect on them with healthcare providers. In addition to positive first impressions, areas for improvement were identified, including the wish for enhanced realism and reduced physical discomfort while immersed in VR. Finally, important factors contributing to the successful introduction of VR were identified. For example, taking into account psychological distress experienced by patients or supporting healthcare providers with implementation resources.Conclusion: The integration of VR into forensic mental healthcare holds great potential for behavior change. However, its immersive characteristics also increase the chance of amplifying psychological distress. This emphasizes the need for caution when using VR– especially when a vulnerable patient group is subjected to triggering scenarios. This study advocates for a gradual introduction of the technology and provides valuable insights into essential elements for this introduction in clinical practice. It highlights that even the initial step of integrating VR into practice – the introduction phase – demands careful planning and a personalized approach. This underscores the need for ongoing refinement and a systematic approach to the overall implementation of VR. These efforts are crucial to fully realize its potential in clinical practice

eHealth technology in forensic mental healthcare:Recommendations for achieving benefits and overcoming barriers

While eHealth technologies such as web-based interventions, mobile apps, and virtual reality have the potential to be of added value for forensic mental healthcare, there is a gap between this potential and the current situation in practice. The goal of this study was to identify recommendations to bridge this gap. In total, 21 semi-structured interviews and 89 questionnaires were conducted in a Dutch forensic mental healthcare sample consisting of professionals, patients, and eHealth experts. Based on the broad range of identified recommendations, it can be concluded that attention should be paid to the characteristics of professionals, patients, technology, and the organization throughout the development, implementation and evaluation of eHealth

Supreme Court Amicus Brief Regarding Wyeth v. Diana Levine

Prominent in arguments opposing preemption of state tort law liability for alleged inadequacies in prescription drug labeling is the argument that such liability can complement FDA regulation by improving on a regulatory scheme that fails to provide adequate deterrence against the marketing of unsafe or inadequately labeled drugs. The premise of this argument is faulty. Fundamental principles of economics and numerous studies of FDA drug regulation reveal that FDA in fact errs on the side of overregulation of prescription drugs. Product liability litigation focused solely on one side of the prescription drug public health equation leads to further distortions of the drug approval and labeling process and exacerbates FDA's inherent overly cautious approach. Preemption of state tort law where it conflicts with FDA requirements will minimize these distortions and thereby maximize public health.Health and Safety, Other Topics

Thermoelastic Noise and Homogeneous Thermal Noise in Finite Sized Gravitational-Wave Test Masses

An analysis is given of thermoelastic noise (thermal noise due to thermoelastic dissipation) in finite sized test masses of laser interferometer gravitational-wave detectors. Finite-size effects increase the thermoelastic noise by a modest amount; for example, for the sapphire test masses tentatively planned for LIGO-II and plausible beam-spot radii, the increase is less than or of order 10 per cent. As a side issue, errors are pointed out in the currently used formulas for conventional, homogeneous thermal noise (noise associated with dissipation which is homogeneous and described by an imaginary part of the Young's modulus) in finite sized test masses. Correction of these errors increases the homogeneous thermal noise by less than or of order 5 per cent for LIGO-II-type configurations.Comment: 10 pages and 3 figures; RevTeX; submitted to Physical Review