361 research outputs found

    The Effect of Nutritional Status on the Presence of Lower-Extremity Stress Fracture in Young Vocational Dancers

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    This research project aims to investigate the effects of nutritional status, and resulting bone mineral density (BMD), on stress fracture incidence in young, female vocational dancers.https://digitalcommons.gardner-webb.edu/exercise-science-research-proposal-posters/1008/thumbnail.jp

    My Father

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    Wilting Magnolias

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    While each story is innately different, they all aim to evaluate the terse topic of relationships. These characters are sometimes fierce, often hilarious, and always honest. From overcoming abuse in a family to a commentary on mental health in romantic partnerships, and even a glimpse into the supernatural, these stories offer a realistic gaze into fiction

    Development of a small area population and housing estimating systems for the City of Omaha

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    The need, for population housing information describing the conditions of our urban areas has become critical for city and county governments in their attempts to deal with such problems as urban growth, inner city decay and redevelopment, location of public facilities, and allocation of city services. No longer can the decennial census inventories be used as the only source of urban information. City and county governments must develop methods of estimating population and housing characteristics between census enumerations that can provide accurate, timely and meaningful information concerning the urban community. This information must then be made available to local decision makers so that they can respond to the needs of their jurisdictions based upon current data about the area’s condition and trends. Estimates for geographic subareas are essential to understanding the internal distribution of population and housing characteristics within cities and their changing patterns over time. The actions of local government in responding to urban problems must be sensitive to changing conditions within specific neighborhoods; thus the need for current estimates by subarea is critical. The urban geographer can make an important contribution to the development and implementation of population and housing estimating procedures within local government. The essential question is the quantification of where, which the geographer is eminently well qualified to answer. The study of the spatial arrangement and distribution of occurrences is at the core of geographic research. Today the skills of the geographer can be applied to help local government respond in an effective way to the problems of our cities

    Ten Day Nutritional Assessment

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    https://digitalcommons.gardner-webb.edu/exercise-science-research-proposal-posters/1060/thumbnail.jp

    Box Step-Up Movement Analysis

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    https://digitalcommons.gardner-webb.edu/exercise-science-research-proposal-posters/1075/thumbnail.jp

    Dominant-negative mutant phenotypes and the regulation of translation elongation factor 2 levels in yeast

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    The eukaryotic translation elongation factor 2 (eEF2), a member of the G-protein superfamily, catalyzes the post-peptidyl transferase translocation of deacylated tRNA and peptidyl tRNA to the ribosomal E- and P-sites. eEF2 is modified by a unique post-translational modification: the conversion of His699 to diphthamide at the tip of domain IV, the region proposed to mimic the anticodon of tRNA. Structural models indicate a hinge is important for conformational changes in eEF2. Mutations of V488 in the hinge region and H699 in the tip of domain IV produce non-functional mutants that when co-expressed with the wild-type eEF2 result in a dominant-negative growth phenotype in the yeast Saccharomyces cerevisiae. This phenotype is linked to reduced levels of the wild-type protein, as total eEF2 levels are unchanged. Changes in the promoter, 5′-untranslated region (5′-UTR) or 3′-UTR of the EFT2 gene encoding eEF2 do not allow overexpression of the protein, showing that eEF2 levels are tightly regulated. The H699K mutant, however, also alters translation phenotypes. The observed regulation suggests that the cell needs an optimum amount of active eEF2 to grow properly. This provides information about a new mechanism by which translation is efficiently maintained

    Redbird Buzz Episode 1: Terri Goss Kinzy, May 2022

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    Interview with Illinois State University\u27s 20th president, Terri Goss Kinzy. The interview was conducted in May 2022 by Rachel Kobus from Alumni Engagement, for the Illinois State University Redbird Buzz Podcast

    Characterization of the SECIS binding protein 2 complex required for the co-translational insertion of selenocysteine in mammals

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    Selenocysteine is incorporated into at least 25 human proteins by a complex mechanism that is a unique modification of canonical translation elongation. Selenocysteine incorporation requires the concerted action of a kink-turn structural RNA (SECIS) element in the 3′ untranslated region of each selenoprotein mRNA, a selenocysteine-specific translation elongation factor (eEFSec) and a SECIS binding protein (SBP2). Here, we analyze the molecular context in which SBP2 functions. Contrary to previous findings, a combination of gel filtration chromatography and co-purification studies demonstrates that SBP2 does not self-associate. However, SBP2 is found to be quantitatively associated with ribosomes. Interestingly, a wild-type but not mutant SECIS element is able to effectively compete with the SBP2 ribosome interaction, indicating that SBP2 cannot simultaneously interact with the ribosome and the SECIS element. This data also supports the hypothesis that SBP2 interacts with one or more kink turns on 28S rRNA. Based on these results, we propose a revised model for selenocysteine incorporation where SBP2 remains ribosome bound except during selenocysteine delivery to the ribosomal A-site

    Public Impact-Focused Research Survey Results

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    The Association of Public and Land Grant Universities (APLU) Council on Research (COR) led an initiative to define, identify, and develop a recommended path forward for public impact research (PIR). A survey was conducted of APLU institution in order to: To characterize the extent of public impact research (PIR) occurring at APLU institutions. To understand how institutions (or leaders within institutions) think about, define, and communicate about this type of work. To provide perspectives about the challenges, opportunities, and rewards that may be associated with this type of scholarship. Responses were received from a diverse set of seventy public and land grant universities (APLU total membership was 239 universities at the time of this survey). Research expenditures at responding institutions ranged from 5milliontoover5 million to over 1 billion in FY 2017, and respondents included Hispanic-serving institutions, historically black universities, IEP-designated universities, and were received from 26 US states and one Canadian province. This document contains the complete set of de-identified responses to the survey. The intent is to make this broadly available and accessible to individuals or groups who may want to further analyze or use these results
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