38 research outputs found

    The Relationship Between Mastication and Cognition

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    Wilson Lines in Warped Space: Dynamical Symmetry Breaking and Restoration

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    The dynamics of Wilson lines integrated along a warped extra dimension has been unknown. We study a five dimensional SU(N) pure gauge theory with Randall-Sundrum warped compactification on S^1/Z_2. We clarify the notion of large gauge transformations that are non-periodic on the covering space for this setup. We obtain Kaluza-Klein expansions of gauge and ghost fields for the most general twists and background gauge field configurations, which break the gauge symmetry at classical level in general. We calculate the one-loop effective potential and find that the symmetry corresponding to the subgroup allowing continuous Wilson lines is dynamically restored. The presented method can be directly applied to include extra fields. The connection to dynamical Scherk-Schwarz supersymmetry breaking in warped space is discussed.Comment: 13 pages, 2 eps figures; references and clarifying remarks added; mass of lightest mode shown more explicitl

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    The purpose of this study is to find relationships between occlusal forces in different sex and age groups and the intake of foods. Occlusal forces were estimated using an occlusal force meter. Separate groups for both males and females were also subdivided by age : yong (10-20 years old) and old (30-50 years old). Food intake was classified according to mastication activities, i. e., biting and chewing. Obtained results included : 1) The occlusal forces of males were stronger than females. 2) No difference in occlusal forces was observed between the yonger and older age groups in both sexes. 3) A tendency was observed in which younger people liked to intake soft foods

    Mastication as a Stress-Coping Behavior

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    Exposure to chronic stress induces various physical and mental effects that may ultimately lead to disease. Stress-related disease has become a global health problem. Mastication (chewing) is an effective behavior for coping with stress, likely due to the alterations chewing causes in the activity of the hypothalamic-pituitary-adrenal axis and autonomic nervous system. Mastication under stressful conditions attenuates stress-induced increases in plasma corticosterone and catecholamines, as well as the expression of stress-related substances, such as neurotrophic factors and nitric oxide. Further, chewing reduces stress-induced changes in central nervous system morphology, especially in the hippocampus and hypothalamus. In rodents, chewing or biting on wooden sticks during exposure to various stressors reduces stress-induced gastric ulcer formation and attenuates spatial cognitive dysfunction, anxiety-like behavior, and bone loss. In humans, some studies demonstrate that chewing gum during exposure to stress decreases plasma and salivary cortisol levels and reduces mental stress, although other studies report no such effect. Here, we discuss the neuronal mechanisms that underline the interactions between masticatory function and stress-coping behaviors in animals and humans

    Association between Mastication, the Hippocampus, and the HPA Axis: A Comprehensive Review

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    Mastication is mainly involved in food intake and nutrient digestion with the aid of teeth. Mastication is also important for preserving and promoting general health, including hippocampus-dependent cognition. Both animal and human studies indicate that mastication influences hippocampal functions through the end product of the hypothalamic-pituitary-adrenal (HPA) axis, glucocorticoid (GC). Epidemiologic studies suggest that masticatory dysfunction in aged individuals, such as that resulting from tooth loss and periodontitis, acting as a source of chronic stress, activates the HPA axis, leading to increases in circulating GCs and eventually inducing various physical and psychological diseases, such as cognitive impairment, cardiovascular disorders, and osteoporosis. Recent studies demonstrated that masticatory stimulation or chewing during stressful conditions suppresses the hyperactivity of the HPA axis via GCs and GC receptors within the hippocampus, and ameliorates chronic stress-induced hippocampus-dependent cognitive deficits. Here, we provide a comprehensive overview of current research regarding the association between mastication, the hippocampus, and HPA axis activity. We also discuss several potential molecular mechanisms involved in the interactions between mastication, hippocampal function, and HPA axis activity
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