IPDE法は検査時間を短縮した心筋血流SPECT画像の画質を改善する

Abstract / Introduction / Materials and Methods / Results / Discussion / Conclusion / Acknowledgments / ReferencesSubmitted by 真弓 小柳 ([email protected]) on 2012-04-23T01:15:33Z No. of bitstreams: 2 med2459.pdf: 655320 bytes, checksum: d26224065554565c2fdb2a547aceefde (MD5) med2459_abstract.pdf: 148361 bytes, checksum: 1726ba20bc28cec66638aeb7c98b2e5a (MD5)Made available in DSpace on 2012-04-23T01:15:33Z (GMT). No. of bitstreams: 2 med2459.pdf: 655320 bytes, checksum: d26224065554565c2fdb2a547aceefde (MD5) med2459_abstract.pdf: 148361 bytes, checksum: 1726ba20bc28cec66638aeb7c98b2e5a (MD5) Previous issue date: 2012医学系学府_保健学Objective / The interpolated projection data estimation processing (IPDE) method increases the amount of projection data by interpolation of the projection data. We examined the usefulness of the IPDE method for ^2^0^1T1 myocardial perfusion imaging (MPI) single photon emission computed tomography (SPECT) with a short acquisition time. / Methods / Forty patients with suspected ischemic heart disease underwent stress ^2^0^1T1-MPI SPECT. Both stress and delayed images were acquired by 4 cycles of 360° continuous rotation with a 90-direction setting for 14 min. The projection data used for reconstruction were 1) all cycle data (T1-90-14min), 2) 2 cycles of data (T1-90-7min), and 3) 2 cycles of data processed using the IPDE method (T1-180IPDE-7min). This study compared the detection of the perfusion defect by the uptake score and the image quality of ^2^0^1T1-MPI SPECT using the normalized mean square error (NMSE). / Results / The uptake score of T1-180IPDE-7min was significantly more concordant with T1-90-14min in comparison to the T1-90-7min (p<0.05). The NMSE of the T1-180IPDE-7 min (1.85±1.06%) was significantly lower than that of the T1-90-7min IPDE improves SPECT MPI 4 (2.07±1.24%) (p<0.05). The degree of improvement by the IPDE method was significantly greater for the delayed ^2^0^1T1-MPI SPECT than for the stress ^2^0^1T1-MPI SPECT (p<0.05). / Conclusion / The IPDE method improved the image quality and secured the diagnostic ability of ^2^0^1T1-MPI SPECT for a short acquisition time. Furthermore, the IPDE method is a simple software program that does not require any expensive equipment or use advanced algorithms. These results suggest the possibility that the IPDE method can be useful as a supporting method for shortening the acquisition time of ^2^0^1T1-MPI SPECT