Potential Woody Biomass Supply Chain Scenarios: A Conceptual Study

Part 2: Sustainable Supply ChainsInternational audienceThe interconnectivity among various business entities and physical functions of woody biomass supply chains requires a system-wide perspective. Extant studies largely focus on individual business units or sets of activities. This paper takes a supply chain perspective to gain an understanding of potential woody biomass supply chains. The study draws insights from an extensive review of literature to conceptualize potential woody biomass supply chain scenarios. Three woody biomass supply chain scenarios and associated logistics activities were defined from the analysis of literature content. They are woody biomass sourcing from forest product manufacturers, forest landowners, and biomass pre-processers. Findings suggest that woody biomass as a marketable commodity creates business opportunities for loggers and forest product manufacturers. In moving forward, infrastructure and technological development is vital, encompassing logging capability and transportation and industrial infrastructure

Beneficial Effect of Methylprednisolone on Cardiac Myocytes in a Rat Model of Severe Brain Injury

Cardiac injury, occurred after traumatic brain injury (TBI), has been recognized for more than a century. Bcl-2 is a key regulatory component of the mitochondrial cell death pathway, and its overexpression is cytoprotective in many cell types. The therapeutic agents, which induce the expression of bcl-2 protein, might provide a new therapy to prevent cardiac myocyte damage following TBI. In this study, we investigated whether methylprednisolone I sodium succinate (MPSS) influences the expression of bcl-2 in the heart. Wistar-Albino female rats underwent TBI (300 g/cm) generated by the weight-drop method, and were left untreated (n = 6) or treated with either MPSS (30 mg/kg) (n = 6) or vehicle (albumin solution) (n = 6). The heart was isolated from each animal with TBI. For comparison, the hearts were isolated from sham-operated (n = 6) and control rats (n = 6). The relative expression of bcl-2 mRNA in the heart was quantitated by real-time polymerase chain reaction. We also assessed lipid peroxidation in the heart tissue by determining the concentration of thiobarbituric acid-reactive substances (TBARs) as an indicator of tissue damage. The bcl-2 expression level was significantly higher in the hearts of MPSS-treated rats compared to that of other TBI groups (p < 0.0001). Moreover, TBI increased the lipid peroxidation in the heart, which was significantly reduced by the treatment with MPSS (p < 0.0001). These findings provide evidence for the efficacy of MPSS in protection of cardiac myocytes to achieve optimal heart donation after TBI in heart transplantation. (c) 2005 Tohoku University Medical Press.WoSScopu