Sickle Cell Disease, 2015 A Patient Advocate’s Perspective

Primer pla de l'ubicació de la placa en record on visqué i morí la cantant catalana. Mesura 0,39 x 0,39 metres i és de llautó, bronze i acer inoxidable

Evidence of Two Distinct Dynamic Critical Exponents in Connection with Vortex Physics

The dynamic critical exponent $z$ is determined from numerical simulations for the three-dimensional (3D) lattice Coulomb gas (LCG) and the 3D XY models with relaxational dynamics. It is suggested that the dynamics is characterized by two distinct dynamic critical indices $z_0$ and $z$ related to the divergence of the relaxation time $\tau$ by $\tau\propto \xi^{z_0}$ and $\tau\propto k^{-z}$, where $\xi$ is the correlation length and $k$ the wavevector. The values determined are $z_0\approx 1.5$ and $z\approx 1$ for the 3D LCG and $z_0\approx 1.5$ and $z\approx 2$ for the 3D XY model. It is argued that the nonlinear $IV$ exponent relates to $z_0$, whereas the usual Hohenberg-Halperin classification relates to $z$. Possible implications for the interpretation of experiments are pointed out. Comparisons with other existing results are discussed.Comment: to appear in PR

Acute effects of elevated NEFA on vascular function: a comparison of SFA and MUFA

There is emerging evidence to show that high levels of NEFA contribute to endothelial dysfunction and impaired insulin sensitivity. However, the impact of NEFA composition remains unclear. A total of ten healthy men consumed test drinks containing 50 g of palm stearin (rich in SFA) or high-oleic sunflower oil (rich in MUFA) on separate occasions; a third day included no fat as a control. The fats were emulsified into chocolate drinks and given as a bolus (approximately 10 g fat) at baseline followed by smaller amounts (approximately 3 g fat) every 30 min throughout the 6 h study day. An intravenous heparin infusion was initiated 2 h after the bolus, which resulted in a three- to fourfold increase in circulating NEFA level from baseline. Mean arterial stiffness as measured by digital volume pulse was higher during the consumption of SFA (P,0·001) but not MUFA (P¼0·089) compared with the control. Overall insulin and gastric inhibitory peptide response was greater during the consumption of both fats compared with the control (P,0·001); there was a second insulin peak in response to MUFA unlike SFA. Consumption of SFA resulted in higher levels of soluble intercellular adhesion molecule-1 (sI-CAM) at 330 min than that of MUFA or control (P#0·048). There was no effect of the test drinks on glucose, total nitrite, plasminogen activator inhibitor-1 or endothelin-1 concentrations. The present study indicates a potential negative impact of elevated NEFA derived from the consumption of SFA on arterial stiffness and sI-CAM levels. More studies are needed to fully investigate the impact of NEFA composition on risk factors for CVD

Modulation of Negative Index Metamaterials in the Near-IR Range

Optical modulation of the effective refractive properties of a "fishnet" metamaterial with a Ag/Si/Ag heterostructure is demonstrated in the near-IR range and the associated fast dynamics of negative refractive index is studied by pump-probe method. Photo excitation of the amorphous Si layer at visible wavelength and corresponding modification of its optical parameters is found to be responsible for the observed modulation of negative refractive index in near-IR.Comment: 11 figures, 4 figure

Study of the ecological gas for MRPCs

The Multigap Resistive Plate Chamber (MRPC) is a gaseous detector; the performance depends very much on the gas mixture as well as the design. MRPCs are used as a timing device in several collider experiments and cosmic ray experiments thanks to the excellent timing performance. The typical gas mixtures of RPC-type detectors at current experiments are based on the gases $\rm C_2F_4H_2$ and $\rm SF_6$. These gases have very high Global Warming Potential (GWP) values of 1430 and 23900 respectively. The present contribution has been performed as a part of efforts to reduce the amount of greenhouse gases used in high energy experiments. The performance of MRPC has been measured with two different gas mixtures; $\rm C_2F_4H_2$ based gas mixtures and the ecological $\rm C_3F_4H_2$ (HFO-1234ze). A small MRPC was used for the tests. It has an sensitive area of 20 $\times$ 20 $\rm cm^2$; it was been built with 6 gaps of 220 $\mu$m. In normal operation, the strong space charge created within the gas avalanche limits the avalanche's growth. $\rm SF_6$ plays an important part in the process due to its high attachment coefficient at low electric fields. It is thus necessary to find another gas that has a similar attachment coefficient. $\rm CF_{3}I$ is a possible candidate. Tests were performed with this gas added to $\rm C_3F_4H_2$

Does Particulate Matter Modify the Association between Temperature and Cardiorespiratory Diseases?

BACKGROUND: A number of studies have shown that both temperature and air pollution are associated with health outcomes. In assessing air pollution effects, temperature is usually considered a confounder. However, only a few recent studies considered air pollution as confounders while assessing temperature effects. Few studies are available on whether or not air pollution modifies the temperature–disease relationship. METHODS: In this study, we used three parallel Poisson generalized additive models to examine whether particulate matter < 10 μm in aerodynamic diameter (PM(10)) modified the effects of minimum temperature on cardiorespiratory morbidity and mortality in Brisbane, Australia. RESULTS: Results show that PM(10) statistically significantly modified the effects of temperature on respiratory and cardiovascular hospital admissions, all nonexternal-cause mortality, and cardiovascular mortality at different lags. The enhanced adverse temperature effects were found at higher levels of PM(10), but no clear evidence emerged for interactive effects on respiratory and cardiovascular emergency visits. Three parallel models produced similar results, which strengthened the validity of findings. CONCLUSION: We conclude that it is important to evaluate the modification role of air pollution in the assessment of temperature-related health impacts

Tuning the exciton g-factor in single InAs/InP quantum dots

Photoluminescence data from single, self-assembled InAs/InP quantum dots in magnetic fields up to 7 T are presented. Exciton g-factors are obtained for dots of varying height, corresponding to ground state emission energies ranging from 780 meV to 1100 meV. A monotonic increase of the g-factor from -2 to +1.2 is observed as the dot height decreases. The trend is well reproduced by sp3 tight binding calculations, which show that the hole g-factor is sensitive to confinement effects through orbital angular momentum mixing between the light-hole and heavy-hole valence bands. We demonstrate tunability of the exciton g-factor by manipulating the quantum dot dimensions using pyramidal InP nanotemplates