Studies on Hypoxia: XII. Detrimental Effects of Synthetic Polyribonucleotides on Epiphyseal Plates of Rats Exposed to Hypoxia

The effect of different doses of polyadenylic and polyuridylic acids (poly A:U) was studied in control rats and in rats exposed to hypoxia. In the control rats, administration of different doses of poly A:U did not change the thickness of the epiphyseal plate or increase the incorporation of 3H-phenylalanine as judged using radioautography. Rats exposed to hypoxia showed a significant dose-related reduction in the thickness of the epiphyseal plate and 3H-phenylalanine incorporation.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/67926/2/10.1177_00220345760550041701.pd

Antioxidant activity and contents of total phenolic compounds and anthocyanins according to grain colour in several varieties of Sorghum bicolor (L.) Moench

Sorghum bicolor (L.) Moench contains various phenolic compounds such as anthocyanin. Eleven sorghum accessions were classified into five groups by grain colour and their antioxidant activities were measured as well as the contents of total phenolic compounds (TPC) and anthocyanins in sorghum grains. The grain colour was related to TPC content, but not to monomelic anthocyanin content. Moreover, the overall patterns of antioxidant activity levels in 2,2-Diphenyl-1-picrylhydrazyl (DPPH) or 2,2′-Azino-bis (3-ethylbenzothiazoline-6-sulfonic acid) (ABTS) assay were similar to those of the TPC content. Correlations between TPC and anthocyanin contents were statistically significant and positive (P < 0.05). TPC content showed also a strong positive correlation to DPPH and ABTS antioxidant activities. The results provide the basic data for breeding of sorghum varieties containing large amounts of antioxidants

Singlet Fermionic Dark Matter explains DAMA signal

It has been suggested that, considering channeling effect, the order of a few GeV dark matters which are elastically scattered from detector nuclei might be plausible candidates reconciling the DAMA annual modulation signal with the results of other null experiments. We show that Singlet Fermionic Dark Matter can be such a dark matter candidate, simultaneously providing the correct thermal relic density which is consistent with the WMAP data.Comment: 9 pages, 3 figure

Idling Magnetic White Dwarf in the Synchronizing Polar BY Cam. The Noah-2 Project

Results of a multi-color study of the variability of the magnetic cataclysmic variable BY Cam are presented. The observations were obtained at the Korean 1.8m and Ukrainian 2.6m, 1.2m and 38-cm telescopes in 2003-2005, 56 observational runs cover 189 hours. The variations of the mean brightness in different colors are correlated with a slope dR/dV=1.29(4), where the number in brackets denotes the error estimates in the last digits. For individual runs, this slope is much smaller ranging from 0.98(3) to 1.24(3), with a mean value of 1.11(1). Near the maximum, the slope becomes smaller for some nights, indicating more blue spectral energy distribution, whereas the night-to-night variability has an infrared character. For the simultaneous UBVRI photometry, the slopes increase with wavelength from dU/dR=0.23(1) to dI/dR=1.18(1). Such wavelength dependence is opposite to that observed in non-magnetic cataclysmic variables, in an agreement to the model of cyclotron emission. The principal component analysis shows two (with a third at the limit of detection) components of variablitity with different spectral energy distribution, which possibly correspond to different regions of emission. The scalegram analysis shows a highest peak corresponding to the 200-min spin variability, its quarter and to the 30-min and 8-min QPOs. The amplitudes of all these components are dependent on wavelength and luminosity state. The light curves were fitted by a statistically optimal trigonometrical polynomial (up to 4-th order) to take into account a 4-hump structure. The dependences of these parameters on the phase of the beat period and on mean brightness are discussed. The amplitude of spin variations increases with an increasing wavelength and with decreasing brightnessComment: 30pages, 11figures, accepted in Cent.Eur.J.Phy

EUS-Guided Biliary Drainage

The echoendoscopic biliary drainage is an option to treat obstructive jaundices when ERCP drainage fails. These procedures compose alternative methods to the side of surgery and percutaneous transhepatic biliary drainage, and it was only possible by the continuous development and improvement of echoendoscopes and accessories. The development of linear setorial array echoendoscopes in early 1990 brought a new approach to diagnostic and therapeutic dimenion on echoendoscopy capabilities, opening the possibility to perform punction over direct ultrasonographic view. Despite of the high success rate and low morbidity of biliary drainage obtained by ERCP, difficulty could be found at the presence of stent tumor ingrown, tumor gut compression, periampulary diverticula, and anatomic variation. The echoendoscopic technique starts performing punction and contrast of the left biliary tree. When performed from gastric wall, the access is made through hepatic segment III. From duodenum, direct common bile duct punction. Dilatation is required before stent introduction, and a plastic or metallic stent is introduced. This phrase should be replaced by: diathermic dilatation of the puncturing tract is required using a 6F cystostome. The technical success of hepaticogastrostomy is near 98%, and complications are present in 36%: pneumoperitoneum, choleperitoneum, infection, and stent disfunction. To prevent bile leakage, we have used the 2 stent techniques, the first stent introduced was a long uncovered metallic stent (8 or 10 cm), and inside this first stent a second fully covered stent of 6 cm was delivered to bridge the bile duct and the stomach. Choledochoduodenostomy overall success rate is 92% and described complications include, in frequency order, pneumoperitoneum and focal bile peritonitis, present in 19%. By the last 10 years, the technique was especially performed in reference centers, by ERCP experienced groups, and this seems to be a general guideline to safer procedure execution

Possible Supersymmetric Effects on Angular Distributions in B→K∗(→Kπ)ℓ+ℓ−B \to K^* (\to K \pi) \ell^+ \ell^- Decays

We investigate the angular distributions of the rare B decay, $B \to K^* (\to K \pi) \ell^+ \ell^-$, in general supersymmetric extensions of the standard model. We consider the new physics contributions from the operators $O_{7,8,9,10}$ in small invariant mass region of lepton pair. We show that the azimuthal angle distribution of the decay can tell us the new physics effects clearly from the behavior of the distribution, even if new physics does not change the decay rate substantially from the standard model prediction

Broilers fed a low protein diet supplemented with synthetic amino acids maintained growth performance and retained intestinal integrity while reducing nitrogen excretion when raised under poor sanitary conditions

The present study investigated the effects of supplementing a low protein (LP) diet supplemented with key essential amino acids (AA) to broilers on growth performance, intestinal tract function, blood metabolites, and nitrogen excretion when the animals were maintained under various sanitary conditions for 35 D after hatching. Three hundred eighty-four one-day-old male broilers (Ross 308) were randomly allotted to groups that received one of 6 dietary treatments in a 2 × 3 factorial arrangement (i.e., 2 environmental conditions and 3 dietary treatments) to give 8 replicates per treatment. Broilers were challenged with 2 environmental conditions (sanitary vs. poor sanitary). The dietary treatments were (1) high protein (HP) diet, (2) LP diet, and (3) LP diet with synthetic key essential AA (LPA): the LP diet was supplemented with synthetic AA up to the required levels for broilers. On day 14, birds consumed the LP diet impaired growth performance compared with those fed the HP diet, while the average daily weight gain-to-feed conversion ratio of birds fed the LPA diet improved to the level of birds fed the HP diet under poor sanitary conditions (P < 0.05). Broilers raised under poor sanitary conditions and fed the LP diet displayed higher (P < 0.05) zonula occludens (ZO-1) expression on day 14 than broilers fed either the HP or LPA diet. Under sanitary conditions, birds fed HP and LPA diets showed higher villus height and crypt depth compared with those of broilers fed the LP diet on day 35. Moreover, broilers raised in the poor sanitary environment had higher (P < 0.05) serum endotoxins than those raised in the sanitary environment. Broilers fed the LPA diet showed reduced (P < 0.05) nitrogen excretion on days 14 and 35 compared with those fed the LP and HP diets independent of the environment. In conclusion, the LPA diet did not impair growth performance under poor sanitary conditions for 14 D after hatch while resulting in lower nitrogen excretion in any environment conditions throughout the experiment

A Systematic Analysis of the Lepton Polarization Asymmetries in the Rare B Decay, B -> X_s\tau^+\tau^-

The most general model-independent analysis of the lepton polarization asymmetries in the rare B decay, \Bstt, is presented. We present the longitudinal, normal and transverse polarization asymmetries for the $\tau^+$ and $\tau^-$, and combinations of them, as functions of the Wilson coefficients of twelve independent four-Fermi interactions, ten of them local and two nonlocal. These procedures will tell us which type of operators contributes to the process. And it will be very useful to pin down new physics systematically, once we have the experimental data with high statistics and a deviation from the Standard Model is found.Comment: 24 pages, 8 figures, LaTe

Neutralino dark matter stars can not exist

Motivated by the recent "Cosmos Project" observation of dark-matter concentrations with no ordinary matter in the same place, we study the question of the existence of compact objects made of pure dark matter. We assume that the dark matter is neutralino, and compare its elastic and annihilation cross sections. We find that the two cross sections are of the same order of magnitude. This result has a straightforward and important consequence that neutralinos comprising a compact object can not achieve thermal equilibrium. To substantiate our arguments, by solving Oppenheimer-Volkoff equation we constructed a model of the star made of pure neutralinos. We explicitly showed that the condition for the thermal equilibrium supported by the Fermi pressure is never fulfilled inside the star. This neutralino state can not be described by the Fermi-Dirac distribution. Thus, a stable neutralino star, which is supported by the Fermi pressure, can not exist. We also estimated that a stable star can not contain more than a few percents of neutralinos, most of the mass must be in the form of the standard model particles.Comment: published in JHE

Analysis of the Neutralino System in Three--Body Leptonic Decays of Neutralinos

Neutralinos $\tilde{\chi}^0$ in supersymmetric theories, the spin--1/2 Majorana--type superpartners of the U(1) and SU(2) neutral electroweak gauge bosons and SU(2) neutral Higgs bosons, are expected to be among light supersymmetric particles so that they can be produced copiouslyvia direct pair production and/or from cascade decays of other sparticles such as sleptons at the planned Large Hadron Collider and the prospective International Linear Collider. Considering the prospects of having both highly polarized neutralinos and possibility of reconstructing their decay rest frames, we provide a systematic investigation of the three--body leptonic decays of the neutralinos in the minimal supersymmetric standard model and demonstrate alternative ways for probing the Majorana nature of the neutralinos and CP violation in the neutralino system.Comment: Version to appear in Eur.Phys.J.