Developing cultural competence in working with Korean immigrant families

The authors provide an in-depth examination of the historical background, cultural values, family roles, and community contexts of Korean Americans as an aid to both researchers and clinicians in developing cultural competence with this particular group. First, the concept of cultural competence is defined. A brief history of Korean immigration patterns to the United States and demographic information about Korean Americans are reviewed. Second, Korean cultural values, family structure, and family roles are examined as they impact relationships in research and clinical contexts. Three indigenous concepts (cf. L. Kim, 1992) that may be useful in developing cultural competence include haan (suppressed anger), jeong (strong feeling of kinship), and noon-chi (ability to evaluate social situations through implicit cues). Clinical case examples and accounts from a community-based research perspective illustrate these cultural values. Third, important community resources in the Korean American context are highlighted. Links between cultural competence and “ecological pragmatism ” (Kelly, Azelton, Burzette, & Mock, 1994) are discussed. © 2006 Wiley Periodicals, Inc

Magnetic Ordering in the Spin-Ice Candidate Ho2_2Ru2_2O7_7

Neutron scattering measurements on the spin-ice candidate material Ho$_2$Ru$_2$O$_7$ have revealed two magnetic transitions at T $\sim$ 95 K and T $\sim$ 1.4 K to long-range ordered states involving the Ru and Ho sublattices, respectively. Between these transitions, the Ho$^{3+}$ moments form short-ranged ordered spin clusters. The internal field provided by the ordered S=1 Ru$^{4+}$ moments disrupts the fragile spin-ice state and drives the Ho$^{3+}$ moments to order. We have directly measured a slight shift in the Ho$^{3+}$ crystal field levels at 95 K from the Ru ordering.Comment: 4 pages, 5 figures, submitted to Phys. Rev. Letter

Electronic anisotropies revealed by detwinned angle-resolved photo-emission spectroscopy measurements of FeSe

We report high resolution ARPES measurements of detwinned FeSe single crystals. The application of a mechanical strain is used to promote the volume fraction of one of the orthorhombic domains in the sample, which we estimate to be 80$\%$ detwinned. While the full structure of the electron pockets consisting of two crossed ellipses may be observed in the tetragonal phase at temperatures above 90~K, we find that remarkably, only one peanut-shaped electron pocket oriented along the longer $a$ axis contributes to the ARPES measurement at low temperatures in the nematic phase, with the expected pocket along $b$ being not observed. Thus the low temperature Fermi surface of FeSe as experimentally determined by ARPES consists of one elliptical hole pocket and one orthogonally-oriented peanut-shaped electron pocket. Our measurements clarify the long-standing controversies over the interpretation of ARPES measurements of FeSe

Charge transfer complex formation between organic interlayers drives light-soaking in large area perovskite solar cells

Light soaking (LS) is a well-known but poorly understood phenomenon in perovskite solar cells (PSCs) which significantly affects device efficiency and stability. LS is greatly reduced in large-area inverted PSCs when a PC61BM electron transport layer (ETL) is replaced with C60, where the ETL is commonly in contact with a thin bathocuproine (BCP) interlayer. Herein, we identify the key molecular origins of this LS effect using a combination of surface photovoltage, ambient photoemission spectroscopy, Raman spectroscopy, integrated with density functional theory simulations. We find that BCP forms a photoinduced charge-transfer (CT) complex with both C60 and PC61BM. The C60/BCP complex accelerates C60 dimer formation, leading to a favourable cascading energetic landscape for electron extraction and reduced recombination loss. In contrast, the PC61BM/BCP complex suppresses PC61BM dimer formation, meaning that PC61BM dimerisation is not the cause of LS. Instead, it is the slow light-induced formation of the PC61BM/BCP CT complex itself, and the new energetic transport levels associated with it, which cause the much slower and stronger LS effect of PC61BM based PSCs. These findings provide key understanding of photoinduced ETL/BCP interactions and their impact on the LS effect in PSCs

The lifetime of B_c-meson and some relevant problems

The lifetime of the B_c-meson is estimated with consistent considerations on all of the heavy mesons ($B^0, B^\pm, B_s, D^0, D^\pm D_s$) and the double heavy meson B_c. In the estimate, the framework, where the non-spectator effects for nonleptonic decays are taken into account properly, is adopted, and the parameters needed to be fixed are treated carefully and determined by fitting the available data. The bound-state effects in it are also considered. We find that in decays of the meson B_c, the QCD correction terms of the penguin diagrams and the main component terms c_1O_1, c_2O_2 of the effective interaction Lagrangian have direct interference that causes an enhancement about 3 ~ 4% in the total width of the B_c meson.Comment: 27 pages, 0 figur

Itinerancy and Hidden Order in URu2Si2URu_2Si_2

We argue that key characteristics of the enigmatic transition at $T_0= 17.5K$ in $URu_2Si_2$ indicate that the hidden order is a density wave formed within a band of composite quasiparticles, whose detailed structure is determined by local physics. We expand on our proposal (with J.A. Mydosh) of the hidden order as incommnesurate orbital antiferromagnetism and present experimental predictions to test our ideas. We then turn towards a microscopic description of orbital antiferromagnetism, exploring possible particle-hole pairings within the context of a simple one-band model. We end with a discussion of recent high-field and thermal transport experiment, and discuss their implications for the nature of the hidden order.Comment: 18 pages, 7 figures. v2 contains added referenc

Managing toxicities associated with immune checkpoint inhibitors: consensus recommendations from the Society for Immunotherapy of Cancer (SITC) Toxicity Management Working Group.

Cancer immunotherapy has transformed the treatment of cancer. However, increasing use of immune-based therapies, including the widely used class of agents known as immune checkpoint inhibitors, has exposed a discrete group of immune-related adverse events (irAEs). Many of these are driven by the same immunologic mechanisms responsible for the drugs\u27 therapeutic effects, namely blockade of inhibitory mechanisms that suppress the immune system and protect body tissues from an unconstrained acute or chronic immune response. Skin, gut, endocrine, lung and musculoskeletal irAEs are relatively common, whereas cardiovascular, hematologic, renal, neurologic and ophthalmologic irAEs occur much less frequently. The majority of irAEs are mild to moderate in severity; however, serious and occasionally life-threatening irAEs are reported in the literature, and treatment-related deaths occur in up to 2% of patients, varying by ICI. Immunotherapy-related irAEs typically have a delayed onset and prolonged duration compared to adverse events from chemotherapy, and effective management depends on early recognition and prompt intervention with immune suppression and/or immunomodulatory strategies. There is an urgent need for multidisciplinary guidance reflecting broad-based perspectives on how to recognize, report and manage organ-specific toxicities until evidence-based data are available to inform clinical decision-making. The Society for Immunotherapy of Cancer (SITC) established a multidisciplinary Toxicity Management Working Group, which met for a full-day workshop to develop recommendations to standardize management of irAEs. Here we present their consensus recommendations on managing toxicities associated with immune checkpoint inhibitor therapy

Sub-Sets of Cancer Stem Cells Differ Intrinsically in Their Patterns of Oxygen Metabolism

PMCID: PMC3640080This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited

Enhancement of glucosinolate and isothiocyanate profiles in brassicaceae crops: addressing challenges in breeding for cultivation, storage, and consumer-related traits

Glucosinolates (GSLs) and isothiocyanates (ITCs) produced by Brassicaceae plants are popular targets for analysis due to the health benefits associated with them. Breeders aim to increase the concentrations in commercial varieties; however, there are few examples of this. The most well-known is Beneforté broccoli, which has increased glucoraphanin/ sulforaphane concentrations compared to those of conventional varieties. It was developed through traditional breeding methods with considerations for processing, consumption, and health made throughout this process. Many studies presented in the literature do not take a holistic approach, and key points about breeding, cultivation methods, postharvest storage, sensory attributes, and consumer preferences are not properly taken into account. In this review, we draw together data for multiple species and address how such factors can influence GSL profiles. We encourage researchers and institutions to engage with industry and consumers to produce research that can be utilized in the improvement of Brassicaceae crops

Weak Decays Beyond Leading Logarithms

We review the present status of QCD corrections to weak decays beyond the leading logarithmic approximation including particle-antiparticle mixing and rare and CP violating decays. After presenting the basic formalism for these calculations we discuss in detail the effective hamiltonians for all decays for which the next-to-leading corrections are known. Subsequently, we present the phenomenological implications of these calculations. In particular we update the values of various parameters and we incorporate new information on m_t in view of the recent top quark discovery. One of the central issues in our review are the theoretical uncertainties related to renormalization scale ambiguities which are substantially reduced by including next-to-leading order corrections. The impact of this theoretical improvement on the determination of the Cabibbo-Kobayashi-Maskawa matrix is then illustrated in various cases.Comment: 229 pages, 32 PostScript figures (included); uses RevTeX, epsf.sty, rotate.sty, rmpbib.sty (included), times.sty (included; requires LaTeX 2e); complete PostScript version available at ftp://feynman.t30.physik.tu-muenchen.de/pub/preprints/tum-100-95.ps.gz or ftp://feynman.t30.physik.tu-muenchen.de/pub/preprints/tum-100-95.ps2.gz (scaled down and rotated version to print two pages on one sheet of paper