3,864 research outputs found
Analysis of Ready-To-Use-Therapeutic-Food (RUTF) for the Treatment of Acute Malnutrition in Children Ages 6-59 Months in Brong-Ahafo Region, Ghana
From the Washington University Senior Honors Thesis Abstracts (WUSHTA), Spring 2018. Published by the Office of Undergraduate Research. Joy Zalis Kiefer, Director of Undergraduate Research and Associate Dean in the College of Arts & Sciences; Lindsey Paunovich, Editor; Helen Human, Programs Manager and Assistant Dean in the College of Arts and Sciences Mentor: Geoff Child
Septins regulate junctional integrity of endothelial monolayers
Junctional integrity of endothelial monolayers is crucial to control movement of molecules and cells across the endothelium. Examining the structure and dynamics of cell junctions in endothelial monolayers, we discovered a role for septins. Contacts between adjacent endothelial cells were dynamic, with protrusions extending above or below neighboring cells. Vascular endothelial cadherin (VE-cadherin) was present at cell junctions, with a membrane-associated layer of F-actin. Septins localized at cell-junction membranes, in patterns distinct from VE-cadherin and F-actin. Septins assumed curved and scallop-shaped patterns at junctions, especially in regions of positive membrane curvature associated with actin-rich membrane protrusions. Depletion of septins led to disrupted morphology of VE-cadherin junctions and increased expression of VE-cadherin. In videos, septin-depleted cells displayed remodeling at cell junctions; regions with VE-cadherin were broader, and areas with membrane ruffling were wider. Septin depletion and junction disruption led to functional loss of junctional integrity, revealed by decreased transendothelial electric resistance and increased transmigration of immune cells. We conclude that septins, as cytoskeletal elements associated with the plasma membrane, are important for cell junctions and junctional integrity of endothelial monolayers, functioning at regions of positive curvature in support of actin-rich protrusions to promote cadherin-based cell junctions.</jats:p
Pano Duo Recital: Joanna Kim Doyle and Soohyun Yun, Works for Four-Hands on One Piano
KSU School of Music presents Piano Duo Recital, Works for Four-Hands on One Piano, Joanna Kim Doyle and Soohyun Yun.https://digitalcommons.kennesaw.edu/musicprograms/1281/thumbnail.jp
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Patterned, Oscillating, pH-Responsive Actuation Of Polymeric Microstructures In Fluid
Engineering and Applied Science
VisageSynTalk: Unseen Speaker Video-to-Speech Synthesis via Speech-Visage Feature Selection
The goal of this work is to reconstruct speech from a silent talking face
video. Recent studies have shown impressive performance on synthesizing speech
from silent talking face videos. However, they have not explicitly considered
on varying identity characteristics of different speakers, which place a
challenge in the video-to-speech synthesis, and this becomes more critical in
unseen-speaker settings. Our approach is to separate the speech content and the
visage-style from a given silent talking face video. By guiding the model to
independently focus on modeling the two representations, we can obtain the
speech of high intelligibility from the model even when the input video of an
unseen subject is given. To this end, we introduce speech-visage selection that
separates the speech content and the speaker identity from the visual features
of the input video. The disentangled representations are jointly incorporated
to synthesize speech through visage-style based synthesizer which generates
speech by coating the visage-styles while maintaining the speech content. Thus,
the proposed framework brings the advantage of synthesizing the speech
containing the right content even with the silent talking face video of an
unseen subject. We validate the effectiveness of the proposed framework on the
GRID, TCD-TIMIT volunteer, and LRW datasets.Comment: Accepted by ECCV 202
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