Thyrotropic effects of balneotherapy in Truskavets’ spa and their endocrine, vegetative and metabolic accompaniments

Background. Previous studies of the Truskavetsian Scientific School of Balneology have studied the effects of course use of bioactive water Naftussya - the main therapeutic factor of the spa - on plasma levels of thyroid hormones in males and females healthy rats and women with thyroid hyperplasia. In men with chronic cholecystitis, the immediate thyrotropic effects of a single use of Naftussya water have been studied. The aim of this study is thyrotropic effects of balneotherapy in Truskavets’ spa and their endocrine, vegetative and metabolic accompaniments in men and women with chronic cholecystitis and pyelonephritis. Materials and Methods. The object of clinical-physiological observation were 34 men (23-70 years) and 10 women (39-76 years), who underwent rehabilitation treatment of chronic cholecystitis and pyelonephritis in remission in the Truskavets’ spa. The examination was performed twice, before and after a 7-10-day course of balneotherapy. The main object of study was the plasma level of Triiodothyronine. We determined also content in plasma Cortisol, Aldosterone, Testosterone and Calcitonin as well as the parameters of the HRV and metabolism. Results. We find in 16 patients (12 men and 4 women) inhibitory thyrotropic effect, in 22 (16 men and 6 women) neutral, and in 6 men only – enhancing effect of balneotherapy. Each variant of the thyrotropic effect is accompanied by characteristic changes in testosteronemia, calcitoninemia, parathyroid activity, Heart Rate, Baevskiy’s Activity Regulatory Systems Index, HRV-markers of vagal tone, Calciemia as well as VLD and LD lipoproteins Cholesterol plasma. Conclusion. Our data confirmed and supplemented the provisions on the multivariate effects of balneotherapy in the spa of Truskavets’ on the endocrine and autonomic nervous systems and metabolism of patients

Relationships between geomagnetic Ар-indeх and HRV and endocrine parameters in patients with dysfunction of the neuroendocrine-immune complex

Background. Recently, on the example of two cohort of patients, we found that disturbances of the geomagnetic field cause a significant immediate modulating effect on the level of immune parameters in the blood. The data available in the literature give grounds for assumptions about the direct effect of disturbances of the geomagnetic field on immunocytes, and indirectly, through immunotropic neurotransmitters and hormones. Our hypothesis is as follows. Disturbances of the geomagnetic field are perceived by acupuncture points. The information obtained is transmitted to neurons and endocrinocytes, the mediators of which, in turn, affect immunocytes. The purpose of this study is to test this hypothesis. Material and methods. The object of observation were 21 men (24-63 y) and 20 women (30-72 y) with neuroendocrine-immune complex dysfunction. Each patient was tested twice with an interval of 4 days. Retrospectively we recorded the geomagnetic Ap-Index on the day of testing and during the previous 7 days, using resource https://www.spaceweatherlive.com/. Recorded the heart rate variability (HRV) parameters, determined the plasma level of cortisol, triiodothyronine and testosterone. Results. During the week, the average level of Ap-index ranged from 7 to 13 nT. Maximum coefficients of multiple correlation with HRV&Hormonal parameters were detected for Ap-index on 2 (R=0,506) and 7 (R=0,403) days before testing. The canonical correlation between Ap-indices for 7 days before and on the day of testing, and the HRV&Hormonal parameters is 0,766. In turn, the immune parameters are closely related to the HRV&Hormonal parameters (R=0,714). Conclusion. Disturbances of the geomagnetic field (Ap-index) causes a significant immediate modulating effect on the immune, HRV and endocrine parameters, apparently through acupuncture points as polymodal receptors of the ecoceptive sensitivity system

The parameters of gas discharge visualization (biophotonics) correlated with parameters of acupuncture points, EEG, HRV and hormones

Background. Previously we have been shown that exist strong canonical correlation between parameters of GDV and principal neuroendocrine factors of adaptation as well as parameters of leukocytogram, immunity and phagocytosis. This study, conducted on a much expanded contingent, will analyze the relationships between GDV parameters, on the one hand, and the parameters of acupuncture points (APs), EEG, HRV and adaptation hormones, on the other. Material and Methods. We observed twice 31 women and 29 men aged 26-76 years with dysfunction of neuroendocrine-immune complex. In the morning in basal conditions at first registered kirlianogram by the method of GDV by the device “GDV Chamber” (“Biotechprogress”, SPb, RF). Than we registered simultaneously EEG and HRV and recorded electrical conductivity of three pairs of Aps. Finally, a blood sample was taken to determine the plasma levels of the main hormones of adaptation: cortisol, testosterone and triiodothyronine. Results processed by method of canonical analysis, using the software package “Statistica 64”. Results. The coefficient of canonical correlation between the electrical conductivity of APs and gas-discharge image (GDI) parameters is 0,635; between APs and virtual Chakras parameters – 0,614; instead, between APs and GDV parameters as a whole – 0,707. The autonomic-endocrine constellation is somewhat more strongly associated with GDI parameters than with virtual Chakras parameters (0,769 vs 0,712). Additional inclusion of EEG parameters in the neuroendocrine set increases the strength of the canonical correlation to 0,869. Conclusion. The above data, taken together with the previous ones, state that between parameters of neuroendocrine-immune complex and GDV exist strong canonical correlation suggesting suitability of the latter method

Effects of transcutaneous electrical stimulation with the device “VEB” ® on the human body

Background. In 2015, a generator for electrotherapy and stimulation oh human nerve centers was created, called “VEB-1”®. Preliminary observation of volunteers revealed a modulating effect of a four-day course of electrical stimulation on the parameters of electroencephalogram, metabolism, as well as gas-discharge visualization (GDV). In this message, we present the results of the approbation of the device on an expanded contingent of volunteers with the use of additional research methods and a new modification of the device. Material and research methods. The object of observation were employees of the sanatorium “Moldova”, patients with chronic cholecystitis: 19 women 30-62 y and 19 men 25-63 y. In the morning registered HRV (“CardioLab+HRV”, “KhAI-Medica”, Kharkiv, UA), EEG (“NeuroCom Standard”, “KhAI-Medica”, Kharkiv, UA), kirlianogram by the method of GDV (“GDV Chamber”, “Biotechprogress”, SPb, RF), electroconductivity of skin in three pairs of points of acupuncture (“Medissa”), electrokinetic index of buccal epithelium ("Biotest", Kharkiv State University), as well as some endocrine, immune and metabolic parameters. After the initial testing, an transcutaneous electrical stimulation session was performed with a “VEB-1”® or a “VEB-2” devices. The next morning after completing the four-day course, retesting was performed. Results. Electrical stimulation causes a sympathotonic shift in the sympatho-vagal balance and an increase in PSD of delta-rhythm generating neurons combined with a decrease in PSD of beta- and theta-rhythm generating neurons. This is accompanied by increase in phagocytosis and favorable changes in immune, biochemical and biophysical parameters as well as increase in testosterone level in men only. The integral effects on the constellation of registered body parameters of both device modifications do not differ significantly. Conclusion. The "VEB" device exerts an adaptogenic effect on the body through transcutaneous electrical stimulation of neurons