Case Series of Post Covid-19 Vaccine Cervical Lymphadenopathy

Objective: The objective of this case series reporting is to add cervical lymphadenopathy as one of the side effects of the COVID-19 vaccine in the adult population presenting with neck swelling.Materials and Methods: This case series of twenty patients were collected at our facility over a period of six months, from March 2021 to the end of August 2021, with an age interval from 17 years to 52 years. The Post COVID Vaccine window to develop cervical lymphadenopathy was from the 3rd day till the 16th. All patients received their first dose of the COVID vaccine.Results: Out of all the patients, 16 were females and 4 were males. Six female and one male patient developed suppurative ipsilateral upper cervical lymphadenitis, which necessitated hospitalization and surgical intervention with incision and drainage, as well as IV medications.Five patients were admitted by internal medicine for workup and supportive care as they were having generalized symptoms, such as fever, chills, headache, myalgia, and inadequate oral intake. The OMFS department was called for evaluation and to rule out any oral infection. Four patients were diabetics with a mean HbA1C of 6.7% to 7.5%. All of these patients did not have any active dental or salivary gland infections.Eventually, all subjects fully recovered with no residual lymphadenopathy and were followed for a period of two weeks to two months, using ultrasound.Conclusion: Cervical Lymphadenopathy and suppurative lymphadenitis have become increasingly common in patients who received the COVID-19 vaccine. Therefore, it must be referenced for the differential diagnosis of neck swelling, especially during this time

Case Series of Post Covid-19 Vaccine Cervical Lymphadenopathy

Objective: The objective of this case series reporting is to add cervical lymphadenopathy as one of the side effects of the COVID-19 vaccine in the adult population presenting with neck swelling.Materials and Methods: This case series of twenty patients were collected at our facility over a period of six months, from March 2021 to the end of August 2021, with an age interval from 17 years to 52 years. The Post COVID Vaccine window to develop cervical lymphadenopathy was from the 3rd day till the 16th. All patients received their first dose of the COVID vaccine.Results: Out of all the patients, 16 were females and 4 were males. Six female and one male patient developed suppurative ipsilateral upper cervical lymphadenitis, which necessitated hospitalization and surgical intervention with incision and drainage, as well as IV medications.Five patients were admitted by internal medicine for workup and supportive care as they were having generalized symptoms, such as fever, chills, headache, myalgia, and inadequate oral intake. The OMFS department was called for evaluation and to rule out any oral infection. Four patients were diabetics with a mean HbA1C of 6.7% to 7.5%. All of these patients did not have any active dental or salivary gland infections.Eventually, all subjects fully recovered with no residual lymphadenopathy and were followed for a period of two weeks to two months, using ultrasound.Conclusion: Cervical Lymphadenopathy and suppurative lymphadenitis have become increasingly common in patients who received the COVID-19 vaccine. Therefore, it must be referenced for the differential diagnosis of neck swelling, especially during this time

Coping styles in patients with anxiety and depression

Different individuals use different coping styles to cope with their problems. In patients with anxiety and/or depression, these have important implications. The primary objective of our study was to estimate the frequency of different coping mechanisms used by patients with symptoms of anxiety and depression. A descriptive, cross-sectional survey was conducted and patients with symptoms of anxiety and depression were identified using the Aga Khan University\u27s Anxiety and Depression Scale (AKUADS). Coping styles were determined by using the 28-item Brief COPE inventory. We were able to recruit 162 people. The prevalence of anxiety and depression was found to be 34%. Females were more than 2 times likely to have anxiety and depression (P value = 0.024, OR = 2.62). In patients screening positive for AKUADS, religion was the most common coping mechanism identified. Acceptance , Use of instrumental support , and Active coping were other commonly used coping styles. Our findings suggest that religious coping is a common behavior in patients presenting with symptoms anxiety and depression in Pakistan. Knowledge of these coping styles is important in the care of such patients, as these coping methods can be identified and to some extent modified by the treating clinician/psychiatrist

Why pandemic coronavirus (SARS-CoV-2) hit different age groups of people in Southeast Asia? a case study in Bangladesh

The new catastrophe of a novel coronavirus (COVID-19s) with unstable symptoms has rapidly pulled danger to all age groups worldwide. We investigate possible causes of the different nature and demography of COVID-19. We collected and used secondary data from the IEDCR website and “Worldometer” from 1st April to 24th June for the statistical analyses, including multi-criteria decision-making method (MCDM), topsis, advanced topsis, simple additive weighting (SAW) and weighting product method (WPM) and PCA. The total number of known COVID-19 patients in Bangladesh was 122,709 as of 24th June. Radical growth will be found with 4912 cases in one day on 16th July as per the time-series forecasting. The infection rate among the young (<30) was highest, i.e., 37.8%, while the elderly (>60) had the maximum death rate (≈39%). Both of India and Bangladesh, approximately one-third of total COVID-19 cases belong to the under 30 age group. Preliminary observation finds India and Bangladesh have a high risk for young people and the working class. PCA indicates the highest positive association among the youths and the highest negative association among the older. In this study, older age (>60) individuals are in danger with the fifth rank, and the young and working-age people are at comparatively lower risk with a third to the fourth rank in terms of infection rate as indicated by MCDM. 41-50 age group remains at lower risk with the first rank in all cases. The nature of activities of younger people and the poor immunity system of older people are the reason for the non-homogenous attitude toward the coronavirus among different age groups. In Bangladesh, drug addiction, gambling habits, uncontrolled lifestyle, and social obliquity have led the youth through danger, threatening the older age of family and society

Clinical outcomes of sirolimus with eluting stent implantation in coronary artery disease

OBJECTIVE: To evaluate the immediate post procedure, thirty-days, and six-months clinical outcomes of sirolimus-eluting stents (SES) implantation in patients with single and multivessel coronary artery disease (CAD). METHODS: A case series of all consecutive patients undergoing percutaneous coronary interventions (PCI) with SES implantation at Shifa International Hospital, Islamabad, were evaluated at early post-procedure, 30-days and six-months clinical follow-up for the incidence of major adverse cardiac event (MACE). This included death, nonfatal myocardial infarction (MI) and repeat revascularization. RESULTS: Out of 206 consecutive patients, 324 had SES implanted. Cumulative MACE rate was 2.93% and 6% at 30-days and six-months follow-ups respectively. Five patients developed ST-segment elevation MI (STEMI). One patient developed non-STEMI. Emergency Coronary Artery Bypass Grafting (CABG) was done in two patients. Repeat (PCI) was carried in three (1.46%) patients for acute in-stent thrombosis. Diabetes Mellitus and multivessel stenting were found to be the independent predictors for acute in-stent thrombosis (P-value \u3c 0.02 and 0.05 respectively). CONCLUSION: SES implantation in coronary artery disease can be safe and effective MACE at one and six months follow-ups

Efficient synthesis and characterization of Polyaniline@Aluminium–succinate metal-organic frameworks nanocomposite and its application for Zn(II) ion sensing

A new class of conductive metal-organic framework (MOF), polyaniline- aluminum succinate (PANI@Al-SA) nanocomposite was prepared by oxidative polymerization of aniline monomer using potassium persulfate as an oxidant. Several analytical techniques such as FTIR, FE-SEM, EDX, XRD, XPS and TGA-DTA were utilized to characterize the obtained MOFs nanocomposite. DC electrical conductivity of polymer-MOFs was determined by four probe method. A bare glassy carbon electrode (GCE) was modified by nafion/PANI@Al-SA, and examined for Zn (II) ion detection. Modified electrode showed improved efficiency by 91.9%. The modified electrode (PANI@Al-SA/nafion/GCE) exhibited good catalytic property and highly selectivity towards Zn(II) ion. A linear dynamic range of 2.8–228.6 µM was obtained with detection limit of LOD 0.59 µM and excellent sensitivity of 7.14 µA µM−1 cm−2. The designed procedure for Zn (II) ion detection in real sample exhibited good stability in terms of repeatability, reproducibility and not affected by likely interferents. Therefore, the developed procedure is promising for quantification of Zn(II) ion in real samples

Efficient synthesis and characterization of Polyaniline@Aluminium–succinate metal-organic frameworks nanocomposite and its application for Zn(II) ion sensing

A new class of conductive metal-organic framework (MOF), polyaniline- aluminum succinate (PANI@Al-SA) nanocomposite was prepared by oxidative polymerization of aniline monomer using potassium persulfate as an oxidant. Several analytical techniques such as FTIR, FE-SEM, EDX, XRD, XPS and TGA-DTA were utilized to characterize the obtained MOFs nanocomposite. DC electrical conductivity of polymer-MOFs was determined by four probe method. A bare glassy carbon electrode (GCE) was modified by nafion/PANI@Al-SA, and examined for Zn (II) ion detection. Modified electrode showed improved efficiency by 91.9%. The modified electrode (PANI@Al-SA/nafion/GCE) exhibited good catalytic property and highly selectivity towards Zn(II) ion. A linear dynamic range of 2.8–228.6 µM was obtained with detection limit of LOD 0.59 µM and excellent sensitivity of 7.14 µA µM−1 cm−2. The designed procedure for Zn (II) ion detection in real sample exhibited good stability in terms of repeatability, reproducibility and not affected by likely interferents. Therefore, the developed procedure is promising for quantification of Zn(II) ion in real samples

Efficient synthesis and characterization of Polyaniline@Aluminium–succinate metal-organic frameworks nanocomposite and its application for Zn(II) ion sensing

A new class of conductive metal-organic framework (MOF), polyaniline- aluminum succinate (PANI@Al-SA) nanocomposite was prepared by oxidative polymerization of aniline monomer using potassium persulfate as an oxidant. Several analytical techniques such as FTIR, FE-SEM, EDX, XRD, XPS and TGA-DTA were utilized to characterize the obtained MOFs nanocomposite. DC electrical conductivity of polymer-MOFs was determined by four probe method. A bare glassy carbon electrode (GCE) was modified by nafion/PANI@Al-SA, and examined for Zn (II) ion detection. Modified electrode showed improved efficiency by 91.9%. The modified electrode (PANI@Al-SA/nafion/GCE) exhibited good catalytic property and highly selectivity towards Zn(II) ion. A linear dynamic range of 2.8–228.6 µM was obtained with detection limit of LOD 0.59 µM and excellent sensitivity of 7.14 µA µM−1 cm−2. The designed procedure for Zn (II) ion detection in real sample exhibited good stability in terms of repeatability, reproducibility and not affected by likely interferents. Therefore, the developed procedure is promising for quantification of Zn(II) ion in real samples

Efficient synthesis and characterization of Polyaniline@Aluminium–succinate metal-organic frameworks nanocomposite and its application for Zn(II) ion sensing

A new class of conductive metal-organic framework (MOF), polyaniline- aluminum succinate (PANI@Al-SA) nanocomposite was prepared by oxidative polymerization of aniline monomer using potassium persulfate as an oxidant. Several analytical techniques such as FTIR, FE-SEM, EDX, XRD, XPS and TGA-DTA were utilized to characterize the obtained MOFs nanocomposite. DC electrical conductivity of polymer-MOFs was determined by four probe method. A bare glassy carbon electrode (GCE) was modified by nafion/PANI@Al-SA, and examined for Zn (II) ion detection. Modified electrode showed improved efficiency by 91.9%. The modified electrode (PANI@Al-SA/nafion/GCE) exhibited good catalytic property and highly selectivity towards Zn(II) ion. A linear dynamic range of 2.8–228.6 µM was obtained with detection limit of LOD 0.59 µM and excellent sensitivity of 7.14 µA µM−1 cm−2. The designed procedure for Zn (II) ion detection in real sample exhibited good stability in terms of repeatability, reproducibility and not affected by likely interferents. Therefore, the developed procedure is promising for quantification of Zn(II) ion in real samples