The functional purpose of sequencer-programs

При финансовой поддержке Российского гуманитарного научного фонда, проект № 07-06-14162

Enhancement of Hydrodynamic Processes in Oil Pipelines Considering Rheologically Complex High-Viscosity Oils

This paper describes a mathematical model of flow-related hydrodynamic processes for rheologically complex high-viscosity bitumen oil and oil-water suspensions and presents methods to improve the design and performance of oil pipelines

Development of the procurement principles and management system of the «lean production» technology

As a result of continued study as to the Lean Production application, a set of principles was proposed for application of this technology in the machinery production; and a new principle of standardization and flexibility was developed and introduced into such set of principles. In implementing any business processes, this principle allows to focus on standardization of the operations and actions that contributes to the cost reduction unification when implementing these operations. Flexibility enables management of personnel, load of the used equipment, efficient application of the existing facilities (equipment, area). Flexibility of the production processes becomes even more possible and expressed if unified standardized operations exist. Application of this principle was demonstrated on the example, how the machine tool's lubricating-cooling fluid was changed in the production. Procurement management system with a reorder point system was developed; it should be implemented in ZF KAMA, LLC. In the reorder point system, the procurement volume becomes optimal, and it remains unchanged later. The minimum aggregated stock holding and repeated order costs become the optimization criterion. The order is given when the current stock reaches a threshold level. It is assumed here to consider the security stock, which covers the need for the period of alleged delay in delivery

Study of lean production technology application at domestic and foreign enterprises

The study of "Lean Production" technology application experience at foreign and domestic enterprises was performed. The features of lean manufacturing technique application and implementation are revealed at foreign and domestic enterprises in the context of eight criteria. At the country level identified the common grounds in this process are determined at a country level and specific tools are determined implemented at enterprises. A significant gap and lag of Russian companies in the implementation of lean manufacturing technology tools is determined. The main reason of this is an inadequate understanding of scientific and methodological principles concerning "Lean production" concept and its philosophy by domestic experts, the lack of interest among owners in the process of production modernization and the availability of a formal approach to the implementation of lean manufacturing technology among managers.The ways of "Lean production" technology implementation process are determined at domestic enterprises. The main way of a Russian company development is the vector of its ideology and corporate culture development based on the principles of lean manufacturing, as well as on production specifics focused on certain reserves of production components, on the mentality of a Russian consumer, who will eventually lead to transition into a qualitatively different development trajectory with the obtaining of a hopping systemic effect

Technology of Water Purification With Chlorinated Derivatives and Assessment of Risk Associated With Human Exposure to These Substances

In the given paper the authors consider the technology of water purification with consideration to the recommendations of the World Health Organization (WHO), European Union (EU) and standards of developed countries. Carcinogenic Unit Risk (UR) magnitude for people constantly exposed to the analyzed carcinogens in the course of a lifetime is estimated. The authors calculate and evaluate unique carcinogenic risk as a complementary probability of cancer development during the whole life of CR when introducing EU standards into water purification technology

Comparative Analysis of Thermohydraulic Performance of Enhanced Viscous Oil and Oil Product Heaters

© Published under licence by IOP Publishing Ltd. This paper covers the analysis of positive and negative effects produced when enhanced helical hollow beams are installed into oil and oil product heaters if compared to the baseline designs. Special attention is given to the consideration of effect on the complex rheology of high-paraffin oils

Genetic Markers for Detecting the DNA of Pathogenic Borrelia

The aim of the study was to analyze the genetic markers of Lyme disease pathogens, which can be used to specifically indicate maximum number of their strains and isolates. Materials and methods. The nucleotide sequences of various genes of Borrelia garinii, B. afzelii, B. burgdorferi were downloaded from the NCBI database (National Center for Biological Informatization). The occurrence of the analyzed nucleotide sequences in the genetic code of various organisms was determined in the nBLAST software utility. For the design of primers and probes, the Vector NTI 9.1.0 program (“Invitrogen Corporation”, Carlsbad, USA) was used. DNA was isolated using the MAGNO-sorb kit, version 100-200 (“AmpliSens”, Moscow, Russia), according to the manufacturer’s instructions. Primers and probes were synthesized at “Evrogen” company (Moscow, Russia). For PCR, reagents manufactured by “Synthol” company (Moscow, Russia) were applied.Results and discussion. In order to perform the reliable indication of pathogenic Borrelia, specific loci (genes) of B. garinii, B. afzelii, B. burgdorferi, which were significantly different from the genetic code of other representatives of the genus Borrelia and from the DNA of other organisms, have been determined by molecular-genetic methods. As a result of a preliminary determination of the analytical significance of the studied loci, the following genes and loci were selected for further work: pepX, clpA, ospA, p83/100, ospC and flaB, of which the flaB and ospA genes were selected for practical indication of pathogenic Borrelia DNA. The genetic markers of B. burgdorferi and B. afzelii are displayed during amplification of the flaB gene, while B. garinii and B. afzelii occur when the ospA gene is used as a genetic marker

Correlation of balanced socio-economic development of the city and its attractiveness (in the case of Russian cities with population over a million citizens)

© 2015, Mediterranean Center of Social and Educational Research. All rights reserved. This article evaluates balanced socio-economic development of the city and its influence on the territorial attractiveness. The hypothesis, that the cities which are developed in socio-economic balance are more attractive and more competitive, is taken as a base of the research. The article classifies the cities according to their level of balance and evaluates the rate of Russian cities with population over a million

Engineering Background: Modern Formats and Challenges of Conceptual Engineering

© Published under licence by IOP Publishing Ltd. This paper describes the analysis of problems and development perspectives of engineering education in our and other countries. Special attention is given to modern formats of education that motivate creative efforts of engineers-to-be as well as issues of conceptual engineering taking the challenges of modernity into account