Multi drug resistance and &#946-lactamase production by Klebsiella pneumoniae

The extended spectrum -lactamase (ESBL) production and multidrug resistant of Klebsiella pneumoniae in children below 5 years of ages are investigated. The K. pneumoniae strains isolated from patients suffering from intestinal and extra intestinal infection between the 0 - 5 year’s ages of children showed resistant to the three antibiotics (ceftazidime, cefotaxime, ceftriaxone), and coexist with non -lactam resistance and ESBL production. All the strains were susceptibility to the antibiotic,imipenem. Out off 110 strains only 9 strains produced ESBL. The plasmid responsible for the antibiotic resistance and ESBL production can be transferred to recipient Escherichia coli strain