Multiple logistic regression analysis of the effect of APOEε4 status on likelihood of having WMH volume in highest vs. lowest quartile (final model).

<p>APOE = apolipoprotein E; WMH = white matter hyperintensities; CI = confidence interval.</p

Demographic and clinical characteristics, lowest vs. highest WMH quartile.

<p>WMH = white matter hyperintensities; OH = orthostatic hypotension; BP = blood pressure; AD = Alzheimer’s disease; APOE = apolipoprotein E.</p>*<p>Mann-Whitney U-test, all other comparisons Chi-Square or Fisher’s Exact test.</p><p>Significant results are shown in <b>bold</b> typeface.</p

Multiple logistic regression analysis of the effect of age on likelihood of having Scheltens deep WMH score in highest vs. lowest quartile (final model).

<p>APOE = Apolipoprotein E; WMH = white matter hyperintensities; CI = confidence interval.</p

Demographic and clinical characteristics.

<p>IQR = interquartile range; MMSE = Mini-Mental State Examination, normal range 24–30; AD = Alzheimer’s Disease; DLB = Dementia with Lewy Bodies; PDD = Parkinson’s Disease Dementia; VaD = vascular dementia; FTD = Frontotemporal Dementia; CIRS = Cumulative Illness Rating Scale, range 0 (no impairment)-52 (extremely severe impairment); APOE = Apolipoprotein E.</p>*<p>antianginals, antihypertensives, tricyclic antidepressants, paroxetine,MAO inhibitors, dopamine agonists, diazepam, dipyridamole, phenothiazines, clozapine, quetiapine, haloperidol.</p><p>Significant results are shown in <b>bold</b> typeface.</p