Pattern of prostate cancer among a Nigerian population: A study in a single tertiary care centre

Background: Prostate cancer has become a global health challenge because of its rising morbidity and mortality in males.It is the second cause of cancer death following lung cancer in men.It is rare under the age of 40 and its incidence has been shown to increase exponentially with age. Previously, Prostate cancer was thought to be a disease rare in blacks owing to the fact that not so much was known of the disease.Aim and objectives: The objective of the study was to review the prevalence, pattern of presentation and clinic-pathologic findings of prostate cancer in the Department of Radiotherapy,Lagos University Teaching Hospital (LUTH),between January 2001 to December 2010 in comparison to previous and recent studies globally.Methodology: Data collection for all patients histologically diagnosed with Prostate cancer at the Department of Radiotherapy,LUTH,from 1st of January 2001 to 31st of December 2010 was done.Results: A total of 144 cases with histologically confirmed Prostate cancer seen during the ten year study were analysed.The highest frequency was seen in the year 2010 with 34 cases.The age range was 41 to 81years with a mean of 66.19 ±7.30years.Adenocarcinoma was the commonest histological type with 98.6%.9(6.3%) patients had a positive family history of prostate cancer out of which 3(33.3%) had their brother affected the malignancy. 51(35.4%) patients presented with stage IV disease.18(12.5%) patients had a Gleason's score of 6,10(6.9%) patients had a Gleason's score of 7 and 2(1.4%) patients had a Gleason's score of 10. The most common presenting complaints were bone pains seen in 51(35.4%) patients, frequent night urine and difficulty with micturition seen in 50(34.7%) and 42(29.2%) patients respectively.Conclusion: This study showed that prostate cancer is not as rare as it used to be.Reasons attributed to its rarity then were lack of awareness,poor screening facilities and poor diagnosing technique.Keywords: prostate cancer,presentation,tumour characteristics,Nigeri

Body and nutrient composition of clariasgariepinnus, HETEROBRANCHUS bidorsalis, and their hybrid (HETEROCLARIAS sp)

No Abstract

Recurrent Dermatofibrosarcoma Protuberans in An African Male

Key words: Inadequate tumour resection, Recurrent Dermatofibrosarcoma Protuberans Nig. Medical Practitioner Vol. 44(5/6) 2003: 105-10

Chemical composition and fatty acid profile of edible larva of cirina forda (Westwood)

The nutrient composition of the larva of Cirina forda   (Westwood) was determined. It contained 33.12 ( 0.87 g/100g crude protein, 9.40 ( 0.16 g/100g crude fibre, 12.24 ( 18 g/ 100g fat, 7.12 ( 0.32 gl 100g ash, 38.12 ( 0.65 g/ 100g carbohydrate and gross energy value of 359 ( 2.83 Kcal/ 100g. The larva is an excellent source of minerals and a 100-g dry sample contained phosphorus (1090mg), zinc (8.6mg) iron (64.0mg) potassium (2130mg) and sodium (210mg). The fatty acid profile of Cirina forda larva is characterized by a very high proportion of the polyunsaturated fatty acids, linoleic acid and ( - linolenic acid (53.8%) which is higher than the percentages found in poultry (23.7%) and fish (30.8%) Mono unsaturated fatty acids content was 14.6% while saturated fatty acid constituted 31.6%. The dietetic significance of the polyunsaturated saturated fatty acid ratio of 1.7:1 and the high potassium and low sodium content of Cirina forda larva is discussed

The Management of Keloids by Radiotherapy in Nigeria

A new method of treatment of keloid was compared with an old technique in five hundred and twenty eight Nigerian patients with 617 keloid lesions seen at the Department of Radiation Biology and Radiotherapy, Lagos University Teaching Hospital, between 1969 and 1981. The etiological factors were identified. A total of 337 keloid lesions were excised between 1969 and 1982 and given post-operative superficial radiotherapy from 5 days upwards after excision while 248 lesions treated from 1983 to 1991 received radiotherapy within 72 hours of surgery. 32 lesions in both groups were given radiotherapy alone. Recurrence rate was higher in certain sites, especially the chest wall and also in patients who received radiotherapy late after excision. The factors which influence recurrence and cosmetic results are discussed: NQJHM Vol. 14 (2) 2004: pp. 151-15