225 research outputs found

    Evaluating Lebesgue constants by Chebyshev polynomial meshes on cube, simplex and ball

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    We show that product Chebyshev polynomial meshes can be used, in a fully discrete way, to evaluate with rigorous error bounds the Lebesgue constant, i.e. the maximum of the Lebesgue function, for a class of polynomial projectors on cube, simplex and ball, including interpolation, hyperinterpolation and weighted least-squares. Several examples are presented and possible generalizations outlined. A numerical software package implementing the method is freely available online

    The Association Between Coping Strategies, Resilience, and Flourishing Among Students at Large U.S. University During the COVID-19 Pandemic: A Mixed Methods Research Study

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    Background: Mental illness indicators increased among U.S. university students in recent years; COVID-19 associated disruptions presented additional mental health challenges for students. Aim: This research aimed to assess the relationship between coping strategies identified by university students and scores on resilience and flourishing scales and to identify additional themes that described student experiences during the COVID-19 pandemic. Methods: An online survey was administered to students at a large public Midwestern University. Quantitative data were assessed using nonparametric tests for association and qualitative data were analyzed using cycles of open coding. Results: Most of the 3,473 respondents were female (76.5%) and white (83.6%), with a mean age of 24.67 years (SD = 8.08). The most frequent coping strategy was physical activity participation (n = 712), followed by socializing (n = 507). The highest resilience and flourishing scores were associated with compliance to COVID-19 associated recommendations or spiritual activities. Qualitative themes included the value of focusing on controllable aspects, the need to be strong for others, and the experience of academic overload during transition to online learning. Conclusions: Universities should endeavor to provide ongoing availability of counseling during university disruptions. Universities might also consider proactive efforts to guide students toward proficiency in strategies that improve coping skills, including some that do not center around technology

    2016 Aerial Imagery Acquired to Monitor the Distribution and Abundance of Submerged Aquatic Vegetation in Chesapeake Bay and Coastal Bays

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    Multispectral aerial imagery acquired in 2016 to monitor the distribution and abundance of submerged aquatic vegetation in Chesapeake Bay and coastal bays

    Evaluation of Color Imagery and Direct Referencing for Mapping Submersed Aquatic Vegetation in Chesapeake Bay - Final Report

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    The VIMS Annual Submersed Aquatic Vegetation (SAV) Monitoring Program has used black and white aerial photography to map SAV in Chesapeake Bay each year from 1984 to the present, with the exception of 1988. In 2008, VIMS initiated a pilot project to address two potential enhancements identified by a recent external program review: color film and direct referencing technology. Simultaneous color and black and white imagery was captured for three regions. In addition, GPS/inertial mapping unit (IMU) direct referencing data was acquired for two of the regions

    The worldwide costs of dementia in 2019

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    Introduction: Dementia is a leading cause of death and disability globally. Estimating total societal costs demonstrates the wide impact of dementia and its main direct and indirect economic components. Methods: We constructed a global cost model for dementia, presenting costs as cumulated global and regional costs. Results: In 2019, the annual global societal costs of dementia were estimated at US 1313.4billionfor55.2millionpeoplewithdementia,correspondingtoUS1313.4 billion for 55.2 million people with dementia, corresponding to US 23,796 per person with dementia. Of the total, US 213.2billion(16213.2 billion (16%) were direct medical costs, US 448.7 billion (34%) direct social sector costs (including long-term care), and US 651.4billion(50651.4 billion (50%) costs of informal care. Discussion: The huge costs of dementia worldwide place enormous strains on care systems and families alike. Although most people with dementia live in low- and middle-income countries, highest total and per-person costs are seen in high-income countries. Highlights: Global economic costs of dementia were estimated to reach US 1313.4 in 2019. Sixty-one percent of people with dementia live in low-and middle-income countries, whereas 74% of the costs occur in high-income countries. The impact of informal care accounts for about 50% of the global costs. The development of a long-term care infrastructure is a great challenge for low-and middle-income countries. There is a great need for more cost studies, particularly in low- and middle-income countries. Discussions of a framework for global cost comparisons are needed

    Somatic gene therapy for cancer. The utility of transferrinfection in generating ‘tumor vaccines’

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    The last few years have seen the development of a branch of somatic gene therapy which aims at strengthening the immune surveillance of the body, leading to eradication of disseminated cancer tumor cells and occult micrometastases after surgical removal of the primary tumor. Such a tumor vaccination protocol calls for cultivation of the primary tumor tissue and the insertion of one of three types of genes into the isolated cultured tumor cells followed by irradiation of the transfected or transduced cells to render them incapable of further proliferation. The cells so treated constitute the ‘tumor vaccine’. A review of the literature suggests that for mouse models, in the initial period after inoculation, rejection of the tumor cells is usually effected by non-T-cell immunity, whereas the long-term systemic immune response is based on cytotoxic T-cells. High expression of the gene inserted into the tumor cells may be critical for the success of the vaccination procedure. Examples are given which indicate that transferrinfection, a procedure to introduce genes by adenovirus-augmented receptor-mediated endocytosis, meets some important prerequisites for successful application of this type of gene therapy

    Kinks in the discrete sine-Gordon model with Kac-Baker long-range interactions

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    We study effects of Kac-Baker long-range dispersive interaction (LRI) between particles on kink properties in the discrete sine-Gordon model. We show that the kink width increases indefinitely as the range of LRI grows only in the case of strong interparticle coupling. On the contrary, the kink becomes intrinsically localized if the coupling is under some critical value. Correspondingly, the Peierls-Nabarro barrier vanishes as the range of LRI increases for supercritical values of the coupling but remains finite for subcritical values. We demonstrate that LRI essentially transforms the internal dynamics of the kinks, specifically creating their internal localized and quasilocalized modes. We also show that moving kinks radiate plane waves due to break of the Lorentz invariance by LRI.Comment: 11 pages (LaTeX) and 14 figures (Postscript); submitted to Phys. Rev.

    Telemonitoring Devices and Systems: Current Status and Future Trends

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    In the future, the number of elderly and chronically ill will be quite large. Additionally, pathologies will in many cases be in comorbidity. Alongside this reality, the health care resources will be insufficient for the population, thus the current research for solutions that can be fully implemented in the future. There are available several telemonitoring devices and systems for chronic diseases. Massive use of these devices will be essential to address the current and future lack of health system resources. Research on telemonitoring devices and systems for chronic diseases was con-ducted in academic and scientific databases. The technical specifications were collected in the manufacturers’ web page. The gathered data was analysed and compared in order to propose scenarios for the future trend of technical specifi-cations required in telemonitoring devices/system is performed. Telemonitoring for chronic diseases can bring great benefits to patient and health systems. Widening this practice will be a reality in the near future. This procedure will be fostered by the promotion and regulation of interoperability between de-vices/systems, as well as of front-end programs providing the link between health support systems. Interoperability issues are the main flaw of tedevicesring devices/systems on the market today.info:eu-repo/semantics/publishedVersio

    Telemonitoring Devices and Systems: Current Status and Future Trends

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    In the future, the number of elderly and chronically ill will be quite large. Additionally, pathologies will in many cases be in comorbidity. Along with this reality, the health care resources will be insufficient for the population, thus the current research for technological solutions needs to be implemented in the future. There are available several telemonitoring devices and systems for chronic diseases. Massive use of these devices will be essential to address the current and future lack of health system resources. Research on telemonitoring devices and systems for chronic diseases was conducted in academic and scientific databases. The technical specifications were collected from the manufacturers’ web page. The collected data was analysed and compared in order to propose scenarios for the future trend of technical specifications required in telemonitoring devices/system. Telemonitoring for chronic diseases can bring great benefits to patient and health systems. Widening this practice will be a reality in the near future. This procedure will be fostered by the promotion and regulation of interoperability between devices/systems, as well as of front-end programs providing the link between health support systems. Interoperability issues are the main flaws of telemonitoring devices/systems on the market today.info:eu-repo/semantics/publishedVersio
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