Attenuation of LV remodeling after L-CTS transplantation.

<p>(A) Representative Masson’s trichrome staining at 4 weeks after transplantation. RV, right ventricle (removed). (B) The ratio of fibrotic area to the whole heart area. ***p<0.001. (C) Representative PAS staining of border region at 4 weeks after transplantation. Scale bar = 20 μm. (D) Cardiomyocyte diameter. ***p<0.001. (E) Representative vWF staining 4 weeks after L-CTS transplantation (brown). Scale bar = 20 μm. (F) Capillary density at border region. ***p<0.001. (G) Representative Ku80 staining (brown). Scale bar = 20 μm.</p

Transplantation of L-CTSs onto porcine infarct hearts.

<p>(A) Time course of the animal experiments. MI, myocardial infarction; UCG, ultrasound cardiogram (echocardiogram); LVG, left ventriculogram; Tx, treatment. (B) Surgical view during L-CTS transplantation. The first L-CTS is shown at black arrow and the second L-CTS is shown at white arrow. (C) M-mode view of the echocardiogram. Dotted yellow lines indicate the endocardial boundary of anterior or posterior wall. PreTx, before transplantation; Tx2w, 2 weeks after transplantation. (D) systolic function after transplantation. *p<0.05 vs Sham, ‡p<0.01 vs PreTx. (E) Left ventriculogram at 4 weeks after transplantation. Red: end-diastolic phase, orange: end-systolic phase. (F) Ejection fraction calculated by left ventriculogram. *p<0.05 vs Sham. PreMI, before MI induction.</p

Regional wall motion evaluated by circumference strain at mid region.

<p>Regional wall motion evaluated by circumference strain at mid region.</p

Regional wall motion evaluated by circumference strain at base region.

<p>Regional wall motion evaluated by circumference strain at base region.</p

Baseline characteristics, medications, angiographic and procedural characteristics during the index hospitalization in the propensity score-matched cohort.

(DOCX)</p

Kaplan-Meier event curves for clinical outcomes in patients with two-vessel disease including LAD.

(TIF)</p

Clinical outcomes: PCI group versus CABG group in patients with two-vessel disease who underwent multi-vessel revascularization including LAD.

(DOCX)</p

List of clinical research coordinators.

(DOCX)</p

Angiographic and procedural characteristics: PCI group versus CABG group.

Angiographic and procedural characteristics: PCI group versus CABG group.</p

Kaplan-Meier event curves for clinical outcomes in patients with two-vessel or three-vessel disease including proximal LAD.

(TIF)</p