29 research outputs found

    Herbert Hoover: A Life/Herbert Hoover in the White House: The Ordeal of the Presidency

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    Review of: Herbert Hoover: A Life , by Glen Jeansonne and of Herbert Hoover in the White House: The Ordeal of the Presidency , by Charles Rappleye

    Salivary Gland Transcriptomes and Proteomes of Phlebotomus tobbi and Phlebotomus sergenti, Vectors of Leishmaniasis

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    Phlebotomine female sand flies require a blood meal for egg development, and it is during the blood feeding that pathogens can be transmitted to a host. Leishmania parasites are among these pathogens and can cause disfiguring cutaneous or even possibly fatal visceral disease. The Leishmania parasites are deposited into the bite wound along with the sand fly saliva. The components of the saliva have many pharmacologic and immune functions important in blood feeding and disease establishment. In this article, the authors identify and investigate the protein components of saliva of two important vectors of leishmaniasis, Phlebotomus tobbi and P. sergenti, by sequencing the transcriptomes of the salivary glands. We then compared the predicted protein sequences of these salivary proteins to those of other bloodsucking insects to elucidate the similarity in composition, structure, and enzymatic activity. Finally, this descriptive analysis of P. tobbi and P. sergenti transcriptomes can aid future research in identifying molecules for epidemiologic assays and in investigating sand fly-host interactions

    Herbert Hoover: A Life/Herbert Hoover in the White House: The Ordeal of the Presidency

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    Review of: "Herbert Hoover: A Life", by Glen Jeansonne and of "Herbert Hoover in the White House: The Ordeal of the Presidency", by Charles Rappleye

    Hoover: An Extraordinary Life in Extraordinary Times

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    Review of: Hoover: An Extraordinary Life in Extraordinary Times by Kenneth Whyt

    What America owes to Woodrow Wilson

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