Additional file 1: Figure S1. of Oncolytic adenovirus targeting cyclin E overexpression repressed tumor growth in syngeneic immunocompetent mice

Characterization of cyclin E background in murine ED-1 cells. (a) The genomic DNA was isolated from ED-1 cells, and PCR was used to detect cyclin E with sense primer 5'-TTG GCT ATG CTG GAG GAA GTA-3’ and antisense primer 5'-AGT GCT CTT CGG TGG TGT CAT-3’. (b) The cell lysates from parent ED-1 and single-cell clones were immunoblotted for cyclin E proteins. (TIFF 289 kb

Additional file 2: Table S1. of Interim analysis of survival in a prospective, multi-center registry cohort of cutaneous melanoma tested with a prognostic 31-gene expression profile test

Cox regression analysis for distant metastasis-free (DMFS) and overall survival (OS) in the 322-subject cohort. (DOCX 12 kb

Additional file 1: Figure S1. of Interim analysis of survival in a prospective, multi-center registry cohort of cutaneous melanoma tested with a prognostic 31-gene expression profile test

Survival outcomes for stage I/II patients with molecular classification by the 31-gene expression profile test. A) Recurrence-free survival, B) distant metastasis-free survival, and C) overall survival for Class 1 and Class 2 subjects with stage I or stage II disease (n = 282). (TIFF 192 kb