IDENTIFYING POLICY RELEVANT VARIABLES FOR REDUCING CHILDHOOD MALNUTRITION IN RURAL MALI

The paper uses OLS and Logit analyses of household survey data to identify and compare determinants of the health and nutritional status of Malian children living in three distinct agricultural production zones (cotton, millet/sorghum, and irrigated rice). These preliminary results suggest that improvements in health center coverage (e.g., reducing the average distance to a health center from 20 to 10 kilometers) and more diversity in complementary foods after six months of age (two or more different foods during a 24 hour period) have the potential to significantly improve standardized height for age scores. Other factors of importance are mother's incomes, prenatal visits, and parents' standardized heights (reflecting either genetic traits or generations of poor nutrition). Recommendations for reducing Mali's high prevalence of malnutrition include the need to raise awareness of the problem among rural populations. Because rural health workers, local administrators, and parents do not recognize malnutrition as a problem, newly empowered decentralized governments will need some external assistance to get the issue on local agendas and identify potential solutions.Food Consumption/Nutrition/Food Safety,

Knowledge, Attitudes and Practices on Child Feeding and Care: Preliminary Insights from the Project on Linkages between Child Nutrition and Agricultural Growth

Food Consumption/Nutrition/Food Safety, Downloads May 2008-June 2009: 46,

False discovery rate regression: an application to neural synchrony detection in primary visual cortex

Many approaches for multiple testing begin with the assumption that all tests in a given study should be combined into a global false-discovery-rate analysis. But this may be inappropriate for many of today's large-scale screening problems, where auxiliary information about each test is often available, and where a combined analysis can lead to poorly calibrated error rates within different subsets of the experiment. To address this issue, we introduce an approach called false-discovery-rate regression that directly uses this auxiliary information to inform the outcome of each test. The method can be motivated by a two-groups model in which covariates are allowed to influence the local false discovery rate, or equivalently, the posterior probability that a given observation is a signal. This poses many subtle issues at the interface between inference and computation, and we investigate several variations of the overall approach. Simulation evidence suggests that: (1) when covariate effects are present, FDR regression improves power for a fixed false-discovery rate; and (2) when covariate effects are absent, the method is robust, in the sense that it does not lead to inflated error rates. We apply the method to neural recordings from primary visual cortex. The goal is to detect pairs of neurons that exhibit fine-time-scale interactions, in the sense that they fire together more often than expected due to chance. Our method detects roughly 50% more synchronous pairs versus a standard FDR-controlling analysis. The companion R package FDRreg implements all methods described in the paper

A comparison of pilot-scale supersonic direct steam injection to conventional steam infusion and tubular heating systems for the heat treatment of protein-enriched skim milk-based beverages

peer-reviewedDirect supersonic steam injection, direct steam infusion, and indirect tubular heating were each applied to protein-enriched skim milk-based beverages with 4, 6 and 8% (w/w) total protein, and the effect of final heat temperature on the physical properties of these beverages was investigated. Supersonic steam injection resulted in significantly lower levels of denaturation of β-lactoglobulin (34.5%), compared to both infusion (76.3%) and tubular (97.1%) heating technologies. Viscosity, particle size and accelerated physical stability of formulations did not differ significantly between the heating technologies, while noticeable colour differences due to heat treatment (mainly attributed to increasing b* value) were observed, particularly for tubular heating. Overall, the extent of protein denaturation in high-protein dairy products was significantly influenced by the particular heating technology applied. The application of supersonic steam injection technology, with rapid heating and high shear characteristics, may enable differenciated product characteristics for ready-to-drink ambient-delivery high-protein dairy beverages. Industrial relevance: The design and application of novel direct supersonic steam injection technology was comprehensively studied and found to provide significant benefits over direct steam infusion and indirect tubular heating technologies for skim milk-based protein beverages. This type of injection heating system resulted in heat-treated formulations with lower levels of denatured whey proteins, compared to tubular and infusion heating, offering an alternative opportunity to the industry in terms of producing shelf-stable dairy protein beverages

Extracting Dynamic Information from EXAFS: Simultaneous Analysis of Multiple Temperature-Dependent Data

Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/73509/1/S0909049598004336.pd

AGRICULTURE AND RELATED SECTORS IN THE CILSS COUNTRIES: PAST PERFORMANCE AND STRATEGIC CHOICES FOR THE FUTURE

The document identified five priority areas on which to focus future development plans and projects: 1) human resource development; 2)institutional capacity building; 3) rapid and sustainable development of agricultural production; 4) economic growth and diversification; 5) greater regional integration and ties to the world economy. Recognizing that several of these priorities reached beyond its mandate, CILSS recommended that other more qualified regional organizations (ECOWAS, UEMOA) assume their responsibilities in pursuing these objectives. This paper analyzes the past performance, potential for and challenges facing the agricultural sector in the Sahel, focusing on the factors critical to increasing household income and improving food security in the Sahel. It is divided in four parts.Industrial Organization,

Does a New Polyomavirus Contribute to Merkel Cell Carcinoma?

A new technique designed to hunt for non-human transcripts has identified a novel SV40-like virus present in the majority of Merkel cell carcinomas. Here we examine what it will take to determine whether or not this virus contributes to carcinogenesis

Susceptibility to intestinal infection and diarrhoea in Zambian adults in relation to HIV status and CD4 count.

BACKGROUND: The HIV epidemic in sub-Saharan Africa has had a major impact on infectious disease, and there is currently great interest in the impact of HIV on intestinal barrier function. A three year longitudinal cohort study in a shanty compound in Lusaka, Zambia, carried out before anti-retroviral therapy was widely available, was used to assess the impact of HIV on susceptibility to intestinal infectious disease. We measured the incidence and seasonality of intestinal infection and diarrhoea, aggregation of disease in susceptible individuals, clustering by co-habitation and genetic relatedness, and the disease-to-infection ratio. METHODS: Adults living in a small section of Misisi, Lusaka, were interviewed every two weeks to ascertain the incidence of diarrhoea. Monthly stool samples were analysed for selected pathogens. HIV status and CD4 count were determined annually. RESULTS: HIV seroprevalence was 31% and the prevalence of immunosuppression (CD4 count 200 cells/microL or less) was 10%. Diarrhoea incidence was 1.1 episodes per year and the Incidence Rate Ratio for HIV infection was 2.4 (95%CI 1.7-3.3; p < 0.001). The disease-to-infection ratio was increased at all stages of HIV infection. Aggregation of diarrhoea in susceptible individuals was observed irrespective of immunosuppression, but there was little evidence of clustering by co-habitation or genetic relatedness. There was no evidence of aggregation of asymptomatic infections. CONCLUSION: HIV has an impact on intestinal infection at all stages, with an increased disease-to-infection ratio. The aggregation of disease in susceptible individuals irrespective of CD4 count suggests that this phenomenon is not a function of cell mediated immunity

Does a new polyomavirus contribute to Merkel cell carcinoma?

A new polyomavirus has been discovered in Merkel cell carcinomas, but does it contribute to carcinogenesis