86 research outputs found
Women's tennis collegiate coaching portfolio
Access to thesis permanently restricted to Ball State community only.This creative project is a comprehensive overview of women’s collegiate tennis coaching,
including the on-court demands and administrative considerations of the multi-faceted
profession. This study is a blend of research and real-life experience to create an allencompassing
portfolio that others could use to understand collegiate coaching. As a current
Assistant Women’s tennis coach, I have used my everyday experiences in the office, at practice,
recruiting, on match day, and interacting with the athletic department and student-athletes daily
to gain insight and perspective on how to be successful. Furthermore, textbooks, documentaries,
books, and interviews through my Sport Administration graduate school classes as well as my
own textual and oral research on collegiate tennis coaching helped mold the perspectives
exhibited in this portfolio. This project exhibits the tennis aspects of coaching, including my
personal coaching philosophy, technical and tactical strategies, strength and conditioning,
scouting, analysis of competition performance, and a guide to team meetings. The administrative
considerations of collegiate tennis portion examined recruiting, marketing, travel, compliance,
tournament directorship, budget, and institutional partnerships. While this project extensively
exhibits my coaching philosophies and outlooks today, I plan to use this manual as an everevolving
project, as I expect my coaching philosophies and perspectives to change over time as I
work more in the industry and acquire new information.Thesis (M.A.
The Fair Trade Consumer: Attitudes, Behaviors, and Knowledge of Fair Trade Products
Fair trade products have increased in popularity in many developing countries, as social responsibility has become a relevant issue for retail businesses and consumers. Numerous fair trade organizations have emerged, nationally and locally, with the goal of improving the lives of producers in developing countries by creating sustainable businesses and improving the quality of working conditions. Sales of fair trade products have increased in the United States, especially by mainstream retailers. The sales volume of fair trade products continues to increase throughout various retail channels, however, the profile of the fair trade consumer remains unclear.
This study focuses on two research questions: What is the relationship between consumer attitudes towards fair trade and consumer psychographics, demographics, and the level of fair trade knowledge? How do consumer attitudes towards fair trade affect consumer purchase intentions? Consumers who demonstrate positive attitudes about fair trade are hypothesized to have an increased likelihood of purchasing fair trade products. A sample of customers of a local fair trade retailer was invited to participate in a web based survey. The data from survey results suggested that attitudes and fair trade knowledge were the strongest influencers of consumer purchase intentions.
By examining consumer psychographics, demographics, and level of fair trade knowledge, the results of this research will help retailers and fair trade organizations understand the profile characteristics of fair trade consumers, determine correlations with consumer buying behavior, and enable them to more effectively educate and target fair trade customers. Conclusions related to the profile of the US fair trade consumer will allow retailers to expand their businesses and better predict which fair trade product offerings will resonate best with consumers.Department of Human Sciences: Henderson ScholarshipNo embargoAcademic Major: Fashion and Retail Studie
Orally administered extract from \u3ci\u3ePrunella vulgaris\u3c/i\u3e attenuates spontaneous colitis in mdr1a\u3csup\u3e-/-\u3c/sup\u3e mice
AIM: To investigate the ability of a Prunella vulgaris (P. vulgaris) ethanolic extract to attenuate spontaneous typhlocolitis in mdr1a-/- mice.
METHODS: Vehicle (5% ethanol) or P. vulgaris ethanolic extract (2.4 mg/d) were administered daily by oral gavage to mdr1a-/- or wild type FVBWT mice from 6 wk of age up to 20 wk of age. Clinical signs of disease were noted by monitoring weight loss. Mice experiencing weight loss in excess of 15% were removed from the study. At the time mice were removed from the study, blood and colon tissue were collected for analyses that included histological evaluation of lesions, inflammatory cytokine levels, and myeloperoxidase activity.
RESULTS: Administration of P. vulgaris extracts to mdr1a-/- mice delayed onset of colitis and reduced severity of mucosal inflammation when compared to vehicle-treated mdr1a-/- mice. Oral administration of the P. vulgaris extract resulted in reduced (P \u3c 0.05) serum levels of IL-10 (4.6 ± 2 vs 19.4 ± 4), CXCL9 (1319.0 ± 277 vs 3901.0 ± 858), and TNFα (9.9 ± 3 vs 14.8 ± 1) as well as reduced gene expression by more than two-fold for Ccl2, Ccl20, Cxcl1, Cxcl9, IL-1 α, Mmp10, VCAM-1, ICAM, IL-2, and TNFα in the colonic mucosa of mdr1a-/- mice compared to vehicle-treated mdr1a-/- mice. Histologically, several microscopic parameters were reduced (P \u3c 0.05) in P. vulgaris -treated mdr1a-/- mice, as was myeloperoxidase activity in the colon (2.49 ± 0.16 vs 3.36 ± 0.06, P \u3c 0.05). The numbers of CD4+ T cells (2031.9 ± 412.1 vs 5054.5 ± 809.5) and germinal center B cells (2749.6 ± 473.7 vs 4934.0 ± 645.9) observed in the cecal tonsils of P. vulgaris - treated mdr1a-/- were significantly reduced (P \u3c 0.05) from vehicle-treated mdr1a-/- mice. Vehicle-treated mdr1a-/- mice were found to produce serum antibodies to antigens derived from members of the intestinal microbiota, indicative of severe colitis and a loss of adaptive tolerance to the members of the microbiota. These serum antibodies were greatly reduced or absent in P. vulgaris -treated mdr1a-/- mice.
CONCLUSION: The anti-inflammatory activity of P. vulgaris ethanolic extract effectively attenuated the severity of intestinal inflammation in mdr1a-/- mice
The Prevalence of Bacterial Infection in Patients Undergoing Elective ACDF for Degenerative Cervical Spine Conditions: A Prospective Cohort Study With Contaminant Control
Study Design:
Prospective cohort study.
Objectives:
To determine the prevalence of bacterial infection, with the use of a contaminant control, in patients undergoing anterior cervical discectomy and fusion (ACDF).
Methods:
After institutional review board approval, patients undergoing elective ACDF were prospectively enrolled. Samples of the longus colli muscle and disc tissue were obtained. The tissue was then homogenized, gram stained, and cultured in both aerobic and anaerobic medium. Patients were classified into 4 groups depending on culture results. Demographic, preoperative, and postoperative factors were evaluated.
Results:
Ninety-six patients were enrolled, 41.7% were males with an average age of 54 ± 11 years and a body mass index of 29.7 ± 5.9 kg/m2. Seventeen patients (17.7%) were considered true positives, having a negative control and positive disc culture. Otherwise, no significant differences in culture positivity was found between groups of patients. However, our results show that patients were more likely to have both control and disc negative than being a true positive (odds ratio = 6.2, 95% confidence interval = 2.5-14.6). Propionibacterium acnes was the most commonly identified bacteria. Two patients with disc positive cultures returned to the operating room secondary to pseudarthrosis; however, age, body mass index, prior spine surgery or injection, postoperative infection, and reoperations were not associated with culture results.
Conclusion:
In our cohort, the prevalence of subclinical bacterial infection in patients undergoing ACDF was 17.7%. While our rates exclude patients with positive contaminant control, the possibility of contamination of disc cultures could not be entirely rejected. Overall, culture results did not have any influence on postoperative outcomes
Volume 44, Number 1, March 2024 OLAC Newsletter
Digitized March 2024 issue of the OLAC Newsletter
Effect of Divalproex on Brain Morphometry, Chemistry, and Function in Youth at High-Risk for Bipolar Disorder: A Pilot Study
Abstract Objective: Divalproex has been found efficacious in treating adolescents with and at high risk for bipolar disorder (BD), but little is known about the effects of mood stabilizers on the brain itself. We sought to examine the effects of divalproex on the structure, chemistry, and function of specific brain regions in children at high-risk for BD. Methods: A total of 24 children with mood dysregulation but not full BD, all offspring of a parent with BD, were treated with divalproex monotherapy for 12 weeks. A subset of 11 subjects and 6 healthy controls were scanned with magnetic resonance imaging (MRI, magnetic resonance spectroscopy [MRS], and functional MRI [fMRI]) at baseline and after 12 weeks. Results: There were no significant changes in amygdalar or cortical volume found over 12 weeks. Furthermore, no changes in neurometabolite ratios were found. However, we found the degree of decrease in prefrontal brain activation to correlate with degree of decrease in depressive symptom severity. Conclusions: Bipolar offspring at high risk for BD did not show gross morphometric, neurometabolite, or functional changes after 12 weeks of treatment with divalproex. Potential reasons include small sample size, short exposure to medications, or lack of significant neurobiological impact of divalproex in this particular population
Requirement of Male-Specific Dosage Compensation in Drosophila Females—Implications of Early X Chromosome Gene Expression
Dosage compensation equates between the sexes the gene dose of sex chromosomes that carry substantially different gene content. In Drosophila, the single male X chromosome is hypertranscribed by approximately two-fold to effect this correction. The key genes are male lethal and appear not to be required in females, or affect their viability. Here, we show these male lethals do in fact have a role in females, and they participate in the very process which will eventually shut down their function—female determination. We find the male dosage compensation complex is required for upregulating transcription of the sex determination master switch, Sex-lethal, an X-linked gene which is specifically activated in females in response to their two X chromosomes. The levels of some X-linked genes are also affected, and some of these genes are used in the process of counting the number of X chromosomes early in development. Our data suggest that before the female state is set, the ground state is male and female X chromosome expression is elevated. Females thus utilize the male dosage compensation process to amplify the signal which determines their fate
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