Covalent Triazine-Based Frameworks with Ultramicropores and High Nitrogen Contents for Highly Selective CO₂ Capture

Porous organic frameworks (POFs) are a class of porous materials composed of organic precursors linked by covalent bonds. The objective of this work is to develop POFs with both ultramicropores and high nitrogen contents for CO₂ capture. Specifically, two covalent triazine-based frameworks (CTFs) with ultramicropores (pores of width <7 Å) based on short (fumaronitrile, FUM) and wide monomers (1,4-dicyanonaphthalene, DCN) were synthesized. The obtained CTF-FUM and CTF-DCN possess excellent chemical and thermal stability with ultramicropores of 5.2 and 5.4 Å, respectively. In addition, they exhibit excellent ability to selectively capture CO₂ due to ultramicroporous nature. Especially, CTF-FUM-350 has the highest nitrogen content (27.64%) and thus the highest CO₂ adsorption capacity (57.2 cc/g at 298 K) and selectivities for CO₂ over N₂ and CH₄ (102.4 and 20.5 at 298 K, respectively) among all CTF-FUM and CTF-DCN. More impressively, as far as we know, the CO₂/CH₄ selectivity is larger than that of all reported CTFs and ranks in top 10 among all reported POFs. Dynamic breakthrough curves indicate that both CTFs could indeed separate gas mixtures of CO₂/N₂ and CO₂/CH₄ completely

Facile Synthesis of FeOOH Quantum Dots Modified ZnO Nanorods Films via a Metal-Solating Process

In this study, we referenced the formation principle of rust in nature and the FeOOH quantum dots (QDs) were prepared using a metal-solating process. The FeOOH QDs exhibited an average diameter of 3.5 nm with well crystallinity. Furthermore, the as-prepared FeOOH QDs were deposited on ZnO nanorods film as a co-catalyst for water oxidation. The crystal phase, microstructures, and optical properties of the synthesized films were established through X-ray diffraction (XRD), scanning electron microscopy (SEM), transmission electron microscopy (TEM), Raman spectroscopy, and ultraviolet–visible absorption spectroscopy (UV-vis). Applied as a photoanode for solar water splitting, the FeOOH QDs/ZnO nanorods film exhibited a photocurrent density of 0.44 mA/cm² at 1.23 V vs RHE, which is 2.1 times higher than that of pure ZnO film. After the loading of FeOOH QDs, the ZnO photoanode showed higher surface charge injection efficiency (by a factor of ∼2) and better long-term stability. The analysis of electrochemical measurements displayed that, as a co-catalyst of the oxygen evolution reaction, FeOOH QDs resulted in a noticeable cathodic shift of photocurrent onset potential for water oxidation and a remarkable improvement of surface charge injection efficiency. In addition, the metal-solating method can be applied to preparing the other metal oxides QDs, such as WO₃ and ZnO QDs

DataSheet_1_Identification of hub genes within the CCL18 signaling pathway in hepatocellular carcinoma through bioinformatics analysis.docx

IntroductionHepatocellular carcinoma (HCC) is an aggressive malignancy, and CCL18, a marker of M2 macrophage activation, is often associated with tumor immune suppression. However, the role of CCL18 and its signaling pathway in HCC is still limited. Our study focuses on investigating the prognostic impact of CCL18 and its signaling pathway in HCC patients and biological functions in vitro.MethodsHCC-related RNA-seq data were obtained from TCGA, ICGC, and GEO. The 6 hub genes with the highest correlation to prognosis were identified using univariate Cox and LASSO regression analysis. Multivariate Cox regression analysis was performed to assess their independent prognostic potential and a nomogram was constructed. In vitro experiments, including CCK8, EdU, RT-qPCR, western blot, and transwell assays, were conducted to investigate the biological effects of exogenous CCL18 and 6 hub genes. A core network of highly expressed proteins in the high-risk group of tumors was constructed. Immune cell infiltration was evaluated using the ESTIMATE and CIBERSORT packages. Finally, potential treatments were explored using the OncoPredict package and CAMP database.ResultsWe identified 6 survival-related genes (BMI1, CCR3, CDC25C, CFL1, LDHA, RAC1) within the CCL18 signaling pathway in HCC patients. A nomogram was constructed using the TCGA_LIHC cohort to predict patient survival probability. Exogenous CCL18, as well as overexpression of BMI1, CCR3, CDC25C, CFL1, LDHA, and RAC1, can promote proliferation, migration, invasion, stemness, and increased expression of PD-L1 protein in LM3 and MHCC-97H cell lines. In the high-risk group of patients from the TCGA_LIHC cohort, immune suppression was observed, with a strong correlation to 21 immune-related genes and suppressive immune cells.ConclusionExogenous CCL18 promotes LM3 and MHCC-97H cells proliferation, migration, invasion, stemness, and immune evasion. The high expression of BMI1, CCR3, CDC25C, CFL1, LDHA, and RAC1 can serve as a biomarkers for immune evasion in HCC.</p

Reversing the Dye Adsorption and Separation Performance of Metal–Organic Frameworks via Introduction of −SO₃H Groups

In this work, two hydrostable Cr-based metal–organic frameworks (MOFs), MIL-101­(Cr) and MIL-101­(Cr)-SO₃H, were successfully synthesized and applied in the adsorption and separation of ionic dye fluorescein sodium (FS) and cationic dye safranine T (ST). Interestingly, MIL-101­(Cr) can efficiently adsorb FS dye but hardly adsorbs ST dye, and MIL-101­(Cr)-SO₃H exhibits the thoroughly opposite phenomenon. More importantly, the reversed adsorption with high selectivity on the two MOFs can also be attained in the mixed solutions of the dyes. Finally, a mechanism analysis indicates that this significant reversal in performance for the dyes is mainly attributed to the opposite surface charges of the two MOFs caused by −SO₃H groups

Correction to “Two-Dimensional Long-Plate SnWO₄ Photoanodes Exposed Active Facets for Enhanced Solar Water Splitting”

Correction to “Two-Dimensional Long-Plate SnWO4 Photoanodes Exposed Active Facets for Enhanced Solar Water Splitting

Correction to “Oriented CuWO₄ Films for Improved Photoelectrochemical Water Splitting”

Correction to “Oriented CuWO4 Films for Improved Photoelectrochemical Water Splitting