One year psychotropic load by age and gender.

<p>Figure 2A displays one year psychotropic medication load before and after the episode for females with the means (solid lines) and standard error envelopes (dashed lines). Psychotropic medication load increased significantly in the year after compared to the year prior to the episode (p = 0.04). Psychotropic medication load increased with age irrespective of time period and gender (p<0.01), and peaked in the 50–70 age bracket. There was no significant difference between males' and females' psychotropic medication load (p = 0.27).</p

A model of possible pathways for suicide in prisoners.

<p>A model of possible pathways for suicide in prisoners.</p

Social networks and external contacts of male prisoners who made near-lethal suicide attempts (cases) and those who had not (controls).

1<p>Odds ratios not calculated for disorders where number of discordant pairs was less than 10.</p

Life events, experiences of victimization in prison, and exposure to suicide and self-harm of male prisoners who made near-lethal suicide attempts (cases) and those who had not (controls).

1<p>Odds ratios not calculated for disorders where number of discordant pairs was less than 10.</p>2<p>Includes self-harm without suicidal intent and attempted suicide.</p>3<p>Due to missing data, analysis conducted with 49 pairs.</p

DDD per quarter year before and year after the episode by medication group, cumulating quarterly within each year.

<p>Comparison of year prior to and following the episode is potentially inaccurate as patients may be prescribed medication at different times in the two years, i.e., we may not be comparing the same time periods. We therefore investigated whether they were accumulating at the same rate in the two years. Figure 4 depicts the accumulated (total) DDD collected over the year prior to and the year following the episode, broken down into quarters and reported for non-psychotropic, psychotropic, and antidepressants within each quarter. The pace with which patients accumulated prescribed medication was steady over the two years, although the increase was faster over the first three months following the episode compared to the year preceding it.</p

One year medication load by age and gender.

<p>Total medication load increased significantly in the year following the episode compared to beforehand (p<0.01). Figure 1A displays one year total medication load (DDD) for females by age before and after the episode, with the means (solid lines) and standard error envelopes (dashed lines). Females collected significantly more medication in the year after compared to the year prior to the episode (p<0.01), with the increase in DDD collected amounting to 21.2%. The pre-post difference for females gradually increased with age. There was no significant pre-post difference for males.</p

One year non-psychotropic load by age and gender.

<p>Figure 3A displays one year non-psychotropic medication load before and after the episode for females, and Figure 3B displays the corresponding information for males. Solid lines represent the means with dashed lines showing standard error envelopes. There was a significant increase in non-psychotropic medication load in the year after the episode (p<0.01) compared to the year prior to the DSP episode (a 24.3% increase in DDD collected), but this increase was not dependent on gender (p = 0.53). Non-psychotropic medication load increased with age (p<0.01), and females collected more non-psychotropic overall irrespective of age and time period (p = 0.01).</p

Correlation matrix of impulsivity, hostility, self-esteem, aggression and depression scores in all prisoners participating in the study (N = 120).

*<p>p<0.0001 for correlations and case-control comparisons.</p>a<p>Correlation coefficient calculated using Spearman’s rho.</p>b<p>Correlation coefficient calculated using Pearson’s r.</p

Measures used in study of near-lethal suicide attempts in male prisoners.

<p>Measures used in study of near-lethal suicide attempts in male prisoners.</p

Sociodemographic and criminological characteristics of male prisoners who made near-lethal suicide attempts (cases) and those who had not (controls).

1<p>Single includes being divorced, separated or widowed; Married includes having a partner.</p>2<p>Unemployed includes sick/disabled.</p>3<p>Including criminal damage, fraud and forgery.</p>4<p>Including violence, sexual and robbery.</p>5<p>Applies to sentenced prisoners only.</p>6<p>For cases at incident; for controls at interview.</p>7<p>Odds ratio undefined when there is a 0 in one or more cells (McNemar’s chi-square and associated p-value reported where possible when observed values are equal to or greater than 10).</p