The ratio of secreted cytokines measured by luminex analysis in the supernatants of peripheral blood mononuclear cells (PBMC) stimulated with heat killed H37Rv (MOI = 1∶1) for 24 hours.

<p><a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0046481#s3" target="_blank">Results</a> from TB-IRIS patients with multi-drug resistant (MDR) TB are shown in black full circles (n = 7), rifampicin mono-resistant (RM) cases are shown as a cross (n = 3), and fully sensitive (FS) TB cases are shown as open circles (n = 10).</p

Individual patient's data on hkH37Rv stimulated release of IFN-γ, IL-2, IL-10, ratios of IFN-gamma/IL-10, IL-2/IL-10 and ELISpot responses to ESAT-6 and hkH37Rv.

<p>Individual patient's data on hkH37Rv stimulated release of IFN-γ, IL-2, IL-10, ratios of IFN-gamma/IL-10, IL-2/IL-10 and ELISpot responses to ESAT-6 and hkH37Rv.</p

IFN-gamma ELISpot response of peripheral blood mononuclear cells (PBMC) stimulated with a range of <i>Mycobacterium tuberculosis</i> antigens, expressed as IFN-gamma spot forming cells per million (SFC/10⁶) PBMC.

<p>TB-IRIS patients with multi-drug resistant (MDR) TB are shown in black full circles, rifampicin mono-resistant (RM) cases are shown as a cross, and fully sensitive (FS) TB cases are shown as open circles.</p

Multiplex cytokine analysis (corrected for multiple comparisons).

(1)<p>p value comparing FS unstimulated with FS stimulated.</p>(2)<p>p value comparing MDR unstimulated with MDR stimulated.</p>(3)<p>p value comparing FS stimulated with MDR stimulated.</p><p>N/A: comparison not applicable due to very low values.</p