A Rare Complication of Retrograde Ejaculation after Lumbar Sympathetic Block and its Spontaneous Recovery : A Case Report

Article信州医学雑誌 69(1): 53-56(2021)journal articl

A Case of Unresectable Pulmonary Artery Intimal Sarcoma with Prolonged Survival by Chemotherapy

Pulmonary artery intimal sarcoma is a rare malignant tumor. Due to its low prevalence, little is known about efficacious systemic chemotherapies in cases where the tumors are unresectable or metastatic. In addition, the location of the disease can contribute to poor survival regardless of the response to therapy, as the tumor’s position can cause pulmonary artery hypertension either rapidly or chronically. We encountered a case of unresectable pulmonary artery intimal sarcoma with lung metastases. Treatment with several cytotoxic agents resulted in prolonged survival of 14.2 months. Here, we report the clinical course of this case and present a review of the relevant literature

Sevoflurane suppresses noxious stimulus-evoked expression of Fos-like immunoreactivity in the rat spinal cord via activation of endogenous opioid systems

We investigated the antagonism of sevoflurane antinociception by opioid antagonists in the rat formalin test. Formalin injection into the hindpaw of the rat induces the nocifensive flinching behavior and the expression of Fos-like immunoreactivity (Fos-LI) in the spinal cord. Sevoflurane significantly suppressed the flinching behavior and decreased the number of Fos-LI neurons in the dorsal horn of spinal cord compared with the control group. Moreover, pretreatment with intraperitoneal naloxone plus naltrexone antagonized the suppression of flinching behavior and the decrease of the number of Fos-LI neurons produced by 3% sevoflurane. Intraperitoneal opioid antagonists themselves had no effects on both the behavior response and the expression of Fos-LI induced by formalin injection. This study supports the hypothesis that sevoflurane suppresses the nociceptive response, at least in part, by activating endogenous opioid systems

平成22・23年度「独創性のある生命科学研究」個別研究課題 1）神経障害性疼痛におけるケタミン軟膏の有用性

雑誌掲載

【痛みの治療薬-臨床例に基づいた処方の実際-】 痛みに対する漢方薬の使い方

雑誌掲載版ペインクリニックで知っておくべき東洋医学的病態把握法には、八綱、気血水、五臓六腑、六病位がある。東洋医学的診察法には、望診、聞診、問診、切診があり、日常の診療の中で必要に応じてていねいに行う必要がある。ペインクリニックで、漢方薬が良い適応となる頭痛、腰痛、膝関節痛、帯状疱疹関連痛、疼痛性障害を取り上げた。それぞれの疾患に対し、東洋医学的な病態把握法と診察法で証を決め、漢方薬を選択し、治療を行っていくことが大切である

女性麻酔科医だからできること 女性麻酔科医師だからできる優しい小児麻酔

著者

Effects of pedunculopontine nucleus (PPN) stimulation on medioventral medulla (MED) neurons in vitro

出版社