34 research outputs found

    Two-photon Bio-imaging with a Mode-locked Semiconductor Laser

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    Abstract: We demonstrated two-photon imaging of biological tissues by employing a mode-locked semiconductor laser. Kilowatt-peak-power second-harmonic pulses were obtained from amplified 1.55-µm optical pulses, and were used for two-photon excitation. ©2006 Optical Society of America OCIS codes: (140.5960) Semiconductor lasers; (170.3880) Medical and biological imaging. 1

    Possible interpretations of the joint observations of UHECR arrival directions using data recorded at the Telescope Array and the Pierre Auger Observatory

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    Paroxysmal nocturnal hemoglobinuria‐phenotype cells predict a good response to eltrombopag in patients with refractory aplastic anemia

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    Abstract To identify factors affecting responsiveness to eltrombopag (EPAG), we retrospectively analyzed 38 aplastic anemia patients treated with EPAG who were refractory (n = 29) or showed an inadequate response (n = 9) to conventional therapies. The efficacy was evaluated at 16 weeks after starting EPAG and at any given time when the best response was achieved. Hematologic responses were observed in 15 patients (39%) at week 16 and in 25 (66%) at any given time. Ten of 19 (53%) achieved transfusion independence. A univariate analysis revealed the presence of PNH‐phenotype cells and the relatively higher platelet counts as associated with a good response to EPAG
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