155 research outputs found
Flight Performance of the AKARI Cryogenic System
We describe the flight performance of the cryogenic system of the infrared
astronomical satellite AKARI, which was successfully launched on 2006 February
21 (UT). AKARI carries a 68.5 cm telescope together with two focal plane
instruments, Infrared Cameras (IRC) and Far Infrared Surveyor (FIS), all of
which are cooled down to cryogenic temperature to achieve superior sensitivity.
The AKARI cryogenic system is a unique hybrid system, which consists of cryogen
(liquid helium) and mechanical coolers (2-stage Stirling coolers). With the
help of the mechanical coolers, 179 L (26.0 kg) of super-fluid liquid helium
can keep the instruments cryogenically cooled for more than 500 days. The
on-orbit performance of the AKARI cryogenics is consistent with the design and
pre-flight test, and the boil-off gas flow rate is as small as 0.32 mg/s. We
observed the increase of the major axis of the AKARI orbit, which can be
explained by the thrust due to thermal pressure of vented helium gas.Comment: 19 pages, 10 figures, and 6 tables. Accepted for publication in the
AKARI special issue of the Publications of the Astronomical Society of Japa
Hyperfine-structure-resolved laser spectroscopy of many-electron highly charged ions
Hyperfine-structures of highly charged ions (HCIs) are favourable
spectroscopic targets for exploring fundamental physics as well as nuclear
properties. Recent proposals of HCI atomic clocks highlight their importance,
especially for many-electron HCIs, and they have been theoretically
investigated by refining atomic-structure calculations. Nonetheless, no
established spectroscopic method is currently available to verify these
theoretical calculations. Here, we demonstrate hyperfine-structure-resolved
laser spectroscopy of HCIs in an electron beam ion trap plasma, employing the
magnetic-dipole transition in 45 of I. Ion-state
manipulation by controlled electron collisions in the well-defined laboratory
plasma enables laser-induced fluorescence spectroscopy of trapped HCIs. The
observed spectrum of evaporatively cooled ions under the low magnetic field
shows remarkable features reflecting the hyperfine-structures. The present
demonstration using the combined optical and plasma approach provides a new
benchmark for state-of-the-art atomic calculations of hyperfine-structures in
many-electron HCIs and offers possibilities for a variety of unexploited
experiments.Comment: 11 pages, 5 figure
Helicobacter cinaedi-associated Carotid Arteritis
A 65-year-old Japanese man with bilateral carotid atherosclerosis presented with right neck pain and fever. Contrast-enhanced computed tomography suggested carotid arteritis, and carotid ultrasonography showed an unstable plaque. The patient developed a cerebral embolism, causing a transient ischemic attack. Helicobacter cinaedi was detected in blood culture, and H. cinaedi-associated carotid arteritis was diagnosed. Empirical antibiotic therapy was administered for 6 weeks. After readmission for recurrent fever, he was treated another 8 weeks. Although the relationship between H. cinaedi infection and atherosclerosis development remains unclear, the atherosclerotic changes in our patient’s carotid artery might have been attributable to H. cinaedi infection
Low body mass index is a risk factor forimpaired endothelium-dependent vasodilation in humans: role of nitric oxide and oxidative stress
AbstractObjectivesThe purpose of this study was to evaluate the relationship between body mass index (BMI), including low BMIs, and endothelial function.BackgroundEpidemiologic study has demonstrated that not only obesity but also a low BMI may be a risk factor for cardiovascular disease.MethodsThe forearm blood flow (FBF) response to acetylcholine (ACh) and isosorbide dinitrate (ISDN) was measured in 87 healthy young men (15 low BMI, 51 normal, 14 obese, and 7 extremely obese).ResultsPlasma concentrations of 8-hydroxy-2′-deoxyguanosine and serum concentrations of malondialdehyde-modified low-density lipoprotein were higher in low BMI, obese, and extremely obese subjects than in normal subjects and were similar among the low BMI, obese, and extremely obese groups. The FBF response to ACh was greater in the normal group than in the other groups (p < 0.001), and was lower in the extremely obese group as compared with the other groups (p < 0.001). The ACh-stimulated vasodilation was similar between the low BMI group and the obese group. The ISDN-stimulated vasodilation was similar in all four groups. There were no significant differences in ACh-stimulated vasodilation between the four groups after the nitric oxide (NO) synthase inhibitor NG-monomethyl-L-arginine infusion. Co-infusion of vitamin C augmented the FBF response to ACh in low BMI, obese, and extremely obese groups—but not in normal BMI group.ConclusionsThese findings suggest that not only obesity but also a low BMI may be a risk factor for impaired endothelium-dependent vasodilation through the increased oxidative stress, leading to the reduced bioavailability of NO
Ultra-high-molecular-weight Polyethylene (UHMWPE) Wing Method for Strong Cranioplasty
We developed a new cranioplasty method that utilizes artificial bone made of ultra-high-molecular-weight polyethylene, with a wedge-shaped edge (UHMWPE Wing). This study shows the methods and data of case series and finite element analyses with the UHMWPE Wing. A circumferential wing was preoperatively designed for a custom-made artificial bone made of UHMWPE to achieve high fixed power and to minimize the usage of cranial implants. Here, we present 4 years of follow-up data and finite element analyses for patients treated with the UHMWPE Wing between February 2015 and February 2019. Eighteen consecutive patients underwent cranioplasty using our UHMWPE Wing design. There were no postoperative adverse events in 17 of the patients for at least 18 months. One case of hydrocephalus experienced screw loosening and graft uplift due to shunt malfunction. Placement of a ventriculo-peritoneal shunt immediately returned the artificial bone to normal position. Finite element analyses revealed that a model using the UHMWPE Wing had the highest withstand load and lowest deformation. This is the first report on the UHMWPE Wing method. This method may enable clinicians to minimize dead space and achieve high strength in cranioplasty
Science Objectives of the Ganymede Laser Altimeter (GALA) for the JUICE Mission
Laser altimetry is a powerful tool for addressing the major objectives of
planetary physics and geodesy, and have been applied in planetary explorations
of the Moon, Mars, Mercury, and the asteroids Eros, and Itokawa. The JUpiter
Icy Moons Explorer (JUICE), led by European Space Agency (ESA), has started
development to explore the emergence of habitable worlds around gas giants. The
Ganymede Laser Altimeter (GALA) will be the first laser altimeter for icy
bodies, and will measure the shape and topography of the large icy moons of
Jupiter, (globally for Ganymede, and using flyby ground-tracks for Europa and
Callisto). Such information is crucial for understanding the formation of
surface features and can tremendously improve our understanding of the icy
tectonics. In addition, the GALA will infer the presence or absence of a
subsurface ocean by measuring the tidal and rotational responses. Furthermore,
it also improves the accuracy of gravity field measurements reflecting the
interior structure, collaborating with the radio science experiment. In
addition to range measurements, the signal strength and the waveform of the
laser pulses reflected from the moon's surface contain information about
surface reflectance at the laser wavelength and small scale roughness.
Therefore we can infer the degrees of chemical and physical alterations, e.g.,
erosion, space weathering, compaction and deposition of exogenous materials,
through GALA measurements without being affected by illumination conditions.
JUICE spacecraft carries ten science payloads including GALA. They work closely
together in a synergistic way with GALA being one of the key instruments for
understanding the evolution of the icy satellites Ganymede, Europa, and
Callisto.Comment: 10 pages, 6 figures, accepted for publication in Trans. JSASS
Aerospace Tech. Japa
Asthma-COPD overlap : prevalence and features
Background Asthma-COPD overlap (ACO) is a disease that shares clinical features of both asthma and COPD. The purpose of this study is to investigate the prevalence and clinical features of ACO. Methods We retrospectively reviewed data for 170 patients with persistent airflow limitation and diagnosed them according to “The Japanese Respiratory Society Guidelines for the Management of ACO 2018”. Results Of the 170 patients, 111 were diagnosed as follows : COPD (74 patients, 66.6%), ACO (34 patients, 30.6%), and asthma (3 patients, 2.8%). There was no significant difference in clinical features between ACO and COPD patients. The following pulmonary function tests were significantly lower in ACO than in COPD patients : forced expiratory volume in 1 second/forced vital capacity, peak expiratory flow, maximal mid-expiratory flow, and the maximum expiratory flow at 50% and 75%. The following respiratory impedance parameters were significantly higher in ACO than in COPD patients : respiratory resistance (Rrs) at 5 Hz (R5), Rrsat 20 Hz (R20), R5-R20, and low-frequency reactance area. Conclusions About 30% of patients with persistent airflow limitation were diagnosed with ACO. ACO patients had lower lung function and higher respiratory impedance compared with COPD patients
X-ray harmonic comb from relativistic electron spikes
X-ray devices are far superior to optical ones for providing nanometre
spatial and attosecond temporal resolutions. Such resolution is indispensable
in biology, medicine, physics, material sciences, and their applications. A
bright ultrafast coherent X-ray source is highly desirable, for example, for
the diffractive imaging of individual large molecules, viruses, or cells. Here
we demonstrate experimentally a new compact X-ray source involving high-order
harmonics produced by a relativistic-irradiance femtosecond laser in a gas
target. In our first implementation using a 9 Terawatt laser, coherent soft
X-rays are emitted with a comb-like spectrum reaching the 'water window' range.
The generation mechanism is robust being based on phenomena inherent in
relativistic laser plasmas: self-focusing, nonlinear wave generation
accompanied by electron density singularities, and collective radiation by a
compact electric charge. The formation of singularities (electron density
spikes) is described by the elegant mathematical catastrophe theory, which
explains sudden changes in various complex systems, from physics to social
sciences. The new X-ray source has advantageous scalings, as the maximum
harmonic order is proportional to the cube of the laser amplitude enhanced by
relativistic self-focusing in plasma. This allows straightforward extension of
the coherent X-ray generation to the keV and tens of keV spectral regions. The
implemented X-ray source is remarkably easily accessible: the requirements for
the laser can be met in a university-scale laboratory, the gas jet is a
replenishable debris-free target, and the harmonics emanate directly from the
gas jet without additional devices. Our results open the way to a compact
coherent ultrashort brilliant X-ray source with single shot and high-repetition
rate capabilities, suitable for numerous applications and diagnostics in many
research fields
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