63 research outputs found

    Mineral paragenesis and its implications in the högbomite-bearing skarn, Sør Rondane Mountains, East Antarctica

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    第2回極域科学シンポジウム/第31回極域地学シンポジウム 11月17日(木) 国立極地研究所 2階大会議

    Real-world management of treatment-naïve diabetic macular oedema : 2-year visual outcome focusing on the starting year of intervention from STREAT-DMO study

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    Background/aims To investigate the yearly change of real-world outcomes for best corrected visual acuity (BCVA) after 2-year clinical intervention for treatment-naïve diabetic macular oedema (DMO). Methods Retrospective analysis of aggregated, longitudinal medical records obtained from 27 retina specialised institutions in Japan from Survey of Treatment for DMO database. A total of 2049 treatment-naïve centre involving DMO eyes of which the initial intervention started between 2010 and 2015, and had been followed for 2 years, were eligible. As interventions, antivascular endothelial growth factor (VEGF) agents, local corticosteroids, macular photocoagulation and vitrectomy were defined. In each eye, baseline and final BCVA, the number of each intervention for 2 years was extracted. Each eye was classified by starting year of interventional treatment. Results Although baseline BCVA did not change by year, 2-year improvement of BCVA had been increased, and reached to +6.5 letters in the latest term. There is little difference among starting year about proportions of eyes which BCVA gained >15 letters, in contrast to those which lost >15 letters were decreased by year. The proportion of eyes receiving anti-VEGF therapy was dramatically increased, while those receiving the other therapies were gradually decreased. The proportion of eyes which maintained socially good vision of BCVA>20/40 has been increased and reached to 59.0% in the latest term. Conclusion For recent years, treatment patterns for DMO have been gradually but certainly changed; as a result, better visual gain, suppression of worsened eyes and better final BCVA have been obtained. Anti-VEGF therapy has become the first-line therapy and its injection frequency has been increasing

    Real-world management of treatment-naïve diabetic macular oedema in Japan : two-year visual outcomes with and without anti-VEGF therapy in the STREAT-DME study

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    Background/Aims To investigate real-world outcomes for best-corrected visual acuity (BCVA) after 2-year clinical intervention for treatment-naïve, centr-involving diabetic macular oedema (DME). Methods Retrospective analysis of longitudinal medical records obtained from 27 institutions specialising in retinal diseases in Japan. A total of 2049 eyes with treatment-naïve DME commencing intervention between 2010 and 2015 who were followed for 2 years were eligible. Interventions for DME included anti-vascular endothelial growth factor (VEGF) therapy, local corticosteroid therapy, macular photocoagulation and vitrectomy. Baseline and final BCVA (logMAR) were assessed. Eyes were classified by the treatment pattern, depending on whether anti-VEGF therapy was used, into an anti-VEGF monotherapy group (group A), a combination therapy group (group B) and a group without anti-VEGF therapy (group C). Results The mean 2-year improvement of BCVA was −0.04±0.40 and final BCVA of >20/40 was obtained in 46.3% of eyes. Based on the treatment pattern, there were 427 eyes (20.9%) in group A, 807 eyes (39.4%) in group B and 815 eyes (39.8%) in group C. Mean improvement of BCVA was −0.09±0.39, –0.02±0.40 and −0.05±0.39, and the percentage of eyes with final BCVA of >20/40 was 49.4%, 38.9%, and 52.0%, respectively. Conclusion Following 2-year real-world management of treatment-naïve DME in Japan, BCVA improved by 2 letters. Eyes treated by anti-VEGF monotherapy showed a better visual prognosis than eyes receiving combination therapy. Despite treatment for DME being selected by specialists in consideration of medical and social factors, a satisfactory visual prognosis was not obtained, but final BCVA remained >20/40 in half of all eyes

    Background Factors Affecting Visual Acuity at Initial Visit in Eyes with Central Retinal Vein Occlusion : Multicenter Study in Japan

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    Purpose: To determine the baseline characteristics of patients with central retinal vein occlusion (CRVO) that were significantly associated with the best-corrected visual acuity (BCVA) at the initial examination. Methods: This was a retrospective multicenter study using the medical records registered in 17 ophthalmological institutions in Japan. Patients with untreated CRVO (≥20-years-of-age) who were initially examined between January 2013 and December 2017 were studied. The patients’ baseline factors that were significantly associated with the BCVA at the initial examination were determined by univariate and multivariate linear regression analyses. Results: Data from 517 eyes of 517 patients were analyzed. Univariate analyses showed that an older age (r = 0.194, p < 0.001) and the right eye (r = −0.103, p < 0.019) were significantly associated with poorer BCVA at the initial visit. Multivariate analyses also showed that an older age (β = 0.191, p < 0.001) and the right eye (β = −0.089, p = 0.041) were significantly associated with poorer BCVA at the initial visit. Conclusions: The results indicate that an older age, a known strong factor, and the right eye were significantly associated with poorer BCVA at the initial visit to the hospital. These results suggest that functional and/or anatomical differences between the right and left eyes may be involved in these results

    ヒガシ ドロンイングモードランド, セール・ロンダーネ サンチ チガク チョウサタイ ホウコク 2008-2009 (JARE-50)

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    第50次日本南極地域観測隊(JARE-50)夏隊・セール・ロンダーネ山地地学調査隊は,山地西部地域の地質調査を実施した(国立極地研究所一般研究プロジェクト,P-5-1:代表・本吉洋一).調査地へは,ドロンイングモードランド航空ネットワークを利用して空路ケープタウンから山地に入った.メンバーの構成は,地質調査担当5名とフィールドアシスタント1名である.調査地では三つのキャンプ(ベースキャンプ,前進キャンプ1および前進キャンプ2)を設営し,75日間すべてテントで生活した.本報告では,セール・ロンダーネ山地地学調査隊の設営,西部の気象条件および野外調査結果を含め,調査計画から実施に至る過程について記述する.The Sør Rondane Mountains field party, part of the summer party of the 50th Japanese Antarctic Research Expedition (JARE-50), consisted of five geologists and one field assistant, and conducted geological fieldwork in the western Sr Rondane Mountains, Eastern Dronning Maud Land, as part of a research project of the National Institute of Polar Research (#P-5-1). The field party accessed the mountains using the Dronning Maud Land Air Network (DROMLAN) from Cape Town to a runway close to the Belgian base, via the Novolazarevskaya runway. The field party made three campsites (Base Camp, Camp 1, and Camp 3) and stayed on the snowfield for 75 days. Here, we report the detailed operation plans and present a summary of the fieldwork, including information on logistics and weather reports for the western Sør Rondane Mountains

    ナンキョク ヤガイ チョウサ ニ オケル タイヨウコウ ハツデン システム ノ カツヨウ ダイ50ジ ニホン ナンキョク チイキ カンソクタイ セール・ロンダーネサンチ チガク チョウサタイ ノ レイ

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    第50次日本南極地域観測隊(第50次隊)夏隊のセール・ロンダーネ山地地学調査隊は67日間におよぶ野外調査を行い,その間に必要な電力を太陽光発電で賄った.今回使用した太陽光発電システム(出力電圧約12 V)の1日あたりの発電量は6724 Ahであった.そして,この調査によって以下の3つの重要なことが明らかとなった.1)南極での野外調査生活に必要な電力は太陽光発電システムにより得ることが可能である.2)最大出力電流2.3 Aの太陽パネルは1日あたり910 Ahを発電する.3)夏季の南極は白夜のために日照が途絶える事はないが,当山地では0000 LTから0500 LT (昭和基地時刻) の間に太陽光発電ができない.The field party in the Sør Rondane Mountains, a part of the summer party of the 50th Japanese Antarctic Research Expedition (JARE-50), performed as outdoor survey using a solar-electric system for field camping over a period of 67 days. The total amount of power generation (output: ca 12V) varied from 67 to 24 Ah/day. We obtained three important conclusions: 1) Electric power is sufficiently supplied from the solar-electric system in the field camp. 2) The solar panel (maximum output 2.3 A) used by JARE-50 generates 9-10Ah/day. 3) The solar panel did not produce electric power during the midnight sun (0000-0500 LT; the time for Showa Station area) in the Antarctic summer season

    高周波DC-DCコンバータ用インダクタ・トランスの銅損低減のための磁束経路制御に関する研究

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    信州大学(Shinshu university)博士(工学)この博士論文は、次の学術雑誌論文を一部に使用しています。 / IEEJ Transactions on Electrical and Electronic Engineering 18(9) :1533-1543(2023); doi:10.1002/tee.23873 © 2023 Institute of Electrical Engineer of Japan and Wiley Periodicals LLC./ International Journal of Applied Electromagnetics and Mechanics 71(S1) :S85-S94(2023); doi:10.3233/JAE-220124 / IEEE Transactions on Magnetics 59(11) :8401806(2023); doi:10.1109/TMAG.2023.3294233 © 2023, IEEE/ IEEE Transactions on Magnetics 57(1) :8402109(2021); doi:10.1109/TMAG.2021.3113998 © 2021, IEEEThesis志村 和大. 高周波DC-DCコンバータ用インダクタ・トランスの銅損低減のための磁束経路制御に関する研究. 信州大学, 2024, 博士論文. 博士(工学), 甲第824号, 令和06年03月20日授与.doctoral thesi
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