Optimization of capacitive coupled Low Gain Avalanche Diode (AC-LGAD) sensors for precise time and spatial resolution

Capacitive-coupled Low-Gain Avalanche Diode (AC-LGAD) sensors are being developed for high-energy particle physics experiments as a detector which provides fast time information with fine spatial resolution. This paper describes optimizations of AC-LGAD sensor fabrication parameters, such as doping concentrations of the gain and electrode layers as well as the AC insulator capacitance, to realize $\mathcal{O}$(10)~\um{} spacial resolution, small charge cross talk to the neighboring electrodes, detection efficiency higher than 99\% at a 10$^{-4}$ fake rate and time resolution of about 30~ps. The radiation tolerance of the sensor is presented. In addition, further application to a device capable of visible and infra-red light detection is discussed.Comment: 11 pages, 25 figures, Submitted to Nuclear Instruments & Methods in physics research A (NIMA

腓骨皮弁による下顎骨再建術術後のインプラント周囲軟組織における治療方法の検討

In maxillofacial reconstruction implant treatment, unsatisfactory soft tissue treatment of the area around the implant may lead to inflammation. As a result, appropriate soft tissue treatment is critical. To the best of our knowledge, there are no studies that compare the different tissue treatment methods available. Hence, in this study, we compare three soft tissue treatment methods around implants after mandibular reconstruction is achieved with a fibula-free flap. Out of 33 patients who underwent mandible reconstruction using fibula-free flaps between 2006 and 2015, 5 were selected for this study. A total of 17 implants were used for treatment by the final prosthetics of the five patients. Three soft tissue treatment methods with free gingival graft (FGG) were evaluated, namely, installing a splint in a modified abutment to protect the wounded area during a palatal mucosa transplant (method 1), installing a splint or dentures to a locator abutment (method 2), and the use of screw-in fixed dentures (method 3). The method that could guarantee the widest keratinized mucosa was the screw-in fixed denture method. The results of our study indicated that employing screw-in fixed dentures for FGG may be a useful soft tissue treatment for mandible reconstruction implants.博士（医学）・乙第1491号・令和2年12月24日Copyright © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/)

ヒト肝硬変にみられる肝腺腫様過形成に関する研究

取得学位 : 博士（医学）, 学位授与番号 : 医博甲第1041号, 学位授与年月日：平成4年3月25日,学位授与年：199