Nucleotide Polymorphisms in the Canine Noggin Gene and Their Distribution Among Dog (Canis lupus familiaris) Breeds

Noggin (NOG) is an important regulator for the signaling of bone morphogenetic proteins. In this study, we sequenced the complete coding sequence of the canine NOG gene and characterized the nucleotide polymorphisms. The sequence length varied from 717 to 729 bp, depending on the number of a 6-bp tandem repeat unit (GGCGCG), an insertion that has not been observed in other mammalian NOG genes investigated to date. It results in extensions of (Gly–Ala)3–5 in the putative NOG protein. To survey the distribution of these tandem repeat polymorphisms, we analyzed 126 individuals in seven dog breeds. We identified only three alleles: (GGCGCG)3, (GGCGCG)4, and (GGCGCG)5. Although the allele frequencies were remarkably different among the breeds, the three alleles were present in all seven of the breeds and did not show any deviation from Hardy–Weinberg equilibrium

ENABLING CYBER‐PHYSICAL‐SOCIAL SYSTEMS(CPSS) FOR A BETTER FUTURE

2012 Japan-Egypt Conference on Electornics, Communications and Computers(JEC-ECC2012) : 2012年3月7日 : Alexandria, Egyp

ENABLING CYBER‐PHYSICAL‐SOCIAL SYSTEMS(CPSS) FOR A BETTER FUTURE

2012 Japan-Egypt Conference on Electornics, Communications and Computers(JEC-ECC2012) : 2012年3月7日 : Alexandria, Egyp

Ambient SoC Enabling Future (CPSS Cyber-Physical “Social” Systems)

Waseda University Ambient GCOE International Workshop on System LSI “Ambient SoC - Now and Beyond”: 2011年11月25日(金) ： 北九州ひびきの学研都市会議場アンビエントGCOE 国際ワークショップ “アンビエントSoC の今，そしてこれから” : 2011年11月25日(金) ： 北九州ひびきの学研都市会議

Innovative Life Enabled by Cyber-Physical “Social” Systems (CPSS)

The 15th East Asia Round Table Meeting (EA-RTM) : 2011年10月12日 ： Busan, Kore

Innovative Life Enabled by Cyber-Physical “Social” Systems (CPSS)

The 15th East Asia Round Table Meeting (EA-RTM) : 2011年10月12日 ： Busan, Kore

Ambient SoC Enabling Future (CPSS Cyber-Physical “Social” Systems)

Waseda University Ambient GCOE International Workshop on System LSI “Ambient SoC - Now and Beyond”: 2011年11月25日(金) ： 北九州ひびきの学研都市会議場アンビエントGCOE 国際ワークショップ “アンビエントSoC の今，そしてこれから” : 2011年11月25日(金) ： 北九州ひびきの学研都市会議