NEW DATA ON THE GEOLOGICAL STRUCTURE OF THE SYNNYR ULTRA-K INTRUSIVE FORMATION

The Synnyrsky massif is the largest intrusive containing ultra-potassium syenites, synnyrites, which are raw materials for the production of potash fertilizers and aluminum. An extensive complex of geological and geochemical studies has been carried out, including exploratory drilling, which was carried out on the massif for the first time. The data obtained made it possible to significantly change the idea of the structure of the massif, including a different look at the regularities of the placement of potash-alumina ores, significantly increasing the ore potential and the reliability of its assessment. The present study discusses the existence within the Synnyrsky complex of the third, previously undetected, large intrusive phase, which has its own geological and geochemical features

Serum uromodulin as an early biomarker of tubular atrophy and interstitial fibrosis in patients with glomerulopathies

Aim. To assess the significance of the serum uromodulin (Tamm-Horsfall protein - THP) concentration (Sumo) as an early biomarker of tubular atrophy (TA) and interstitial renal fibrosis (IF) in patients with glomerulopathies. Materials and methods. 84 patients with glomerulopathy and 11 practically healthy persons (control) were examined. Uromodulin concentrations in serum and urine (Uumo) were measured, renal excretion of this protein and the estimated glomerular filtration rate (eGFR) were established. A semi-quantitative assessment of nephrobioptates was performed. Results and discussion. Sumo decreases with a minimum expression of tubular atrophy (TA) or interstitial fibrosis (IF), when the values of eGFR still remain normal. Variations of such excretory parameters of THP as Uumo, daily excretion, and ratio: urinary uromodulin / urinary creatinine, did not manifest a similar trend. Conclusion. Sumo is promising as an early biomarker of fibrotic and atrophic renal damage. The parameters of renal excretion of THP do not seem to have this property. The reason for the delay in the decline of Uumo in the progression of CKD as compared to the decrease in Sumo seems to be the need to maintain a sufficient Uumo to counteract urinary tract infection and stone formation

РОЛЬ ФАКТОРА РОСТА ФИБРОБЛАСТОВ 23-го ТИПА В РАЗВИТИИ КАРДИОВАСКУЛЯРНЫХ ОСЛОЖНЕНИЙ И НАРУШЕНИЙ КАЛЬЦИЙ-ФОСФОРНОГО ОБМЕНА У ПАЦИЕНТОВ С ХРОНИЧЕСКОЙ БОЛЕЗНЬЮ ПОЧЕК

The review discusses the role of fibroblast growth factor type 23 (FGF-23) in progression of renal dysfunction and its cardiovascular effects, calcium-phosphorus metabolism in patients with chronic kidney disease. Differences in the FGF-23 effects at predialysis stage of chronic kidney disease, in dialysis patients and renal allograft recipients are analyzed.В обзоре рассмотрена роль фактора роста фибробластов 23-го типа (ФРФ 23) в прогрессировании почечной дисфункции, а также его кардиоваскулярные эффекты и влияние на кальций-фосфорный обмен у пациентов с хронической болезнью почек. Рассматриваются различия эффектов ФРФ 23 на додиализной стадии хронической болезни почек, у диализных пациентов и у реципиентов почечного аллотрансплантата

НОВЫЕ ДАННЫЕ О ГЕОЛОГИЧЕСКОМ СТРОЕНИИ СЫННЫРСКОГО УЛЬТРАКАЛИЕВОГО ИНТРУЗИВНОГО МАССИВА

The Synnyrsky massif is the largest intrusive containing ultra-potassium syenites, synnyrites, which are raw materials for the production of potash fertilizers and aluminum. An extensive complex of geological and geochemical studies has been carried out, including exploratory drilling, which was carried out on the massif for the first time. The data obtained made it possible to significantly change the idea of the structure of the massif, including a different look at the regularities of the placement of potash-alumina ores, significantly increasing the ore potential and the reliability of its assessment. The present study discusses the existence within the Synnyrsky complex of the third, previously undetected, large intrusive phase, which has its own geological and geochemical features.Сыннырский массив – крупнейший интрузив, содержащий в своем составе ультракалиевые сиениты, сынныриты, являющиеся сырьем для производства калийных удобрений и алюминия. Выполнен обширный комплекс геолого-геохимических исследований, в том числе поисково-разведочное бурение, которое было проведено на массиве впервые. Полученные данные позволили существенным образом изменить представление о строении массива, в том числе иначе взглянуть на закономерности размещения калийно-глиноземных руд, значительно увеличив рудный потенциал и достоверность его оценки. В настоящем исследовании обсуждается существование в пределах Сыннырского комплекса третьей, ранее не выделяемой, крупной интрузивной фазы, которая имеет свои геолого-геохимические особенности

Effect of the shape of laser irradiation pulses on the geometry of the melt pool

Translated from Russian (Fiz. Khim. Obrab. Mater. 1996 (4) p. 36-42Available from British Library Document Supply Centre-DSC:9023.190(VR-Trans--9144)T / BLDSC - British Library Document Supply CentreSIGLEGBUnited Kingdo

Nanoscale Hemispheres in Novel Mixed-Valent Uranyl Chromate(V,VI), (C₃NH₁₀)₁₀[(UO₂)₁₃(Cr₁₂⁵⁺O₄₂)(Cr⁶⁺O₄)₆(H₂O)₆](H₂O)₆

The structure of a novel mixed-valent chromium uranyl compound, (C₃NH₁₀)₁₀[(UO₂)₁₃(Cr₁₂⁵⁺O₄₂)­(Cr⁶⁺O₄)₆(H₂O)₆]­(H₂O)₆ (<b>1</b>), obtained by the combination of a hydrothermal method and evaporation from aqueous solutions with isopropylammonium, contains uranyl chromate hemispheres with lateral dimensions of 18.9 × 18.5 Ų and a height of about 8 Å. The hemispheres are centered by a UO₈ hexagonal bipyramid surrounded by six dimers of Cr⁵⁺O₅ square pyramids, UO₇ pentagonal bipyramids, and Cr⁶⁺O₄ tetrahedra. The hemispheres are linked into two-dimensional layers so that two adjacent hemispheres are oriented in opposite directions relative to the plane of the layer. From a topological point of view, the hemispheres have the formula U₂₁Cr₂₃ and can be considered as derivatives of nanospherical cluster U₂₆Cr₃₆ composed of three-, four-, and five-membered rings

Nanoscale Hemispheres in Novel Mixed-Valent Uranyl Chromate(V,VI), (C₃NH₁₀)₁₀[(UO₂)₁₃(Cr₁₂⁵⁺O₄₂)(Cr⁶⁺O₄)₆(H₂O)₆](H₂O)₆

The structure of a novel mixed-valent chromium uranyl compound, (C₃NH₁₀)₁₀[(UO₂)₁₃(Cr₁₂⁵⁺O₄₂)­(Cr⁶⁺O₄)₆(H₂O)₆]­(H₂O)₆ (<b>1</b>), obtained by the combination of a hydrothermal method and evaporation from aqueous solutions with isopropylammonium, contains uranyl chromate hemispheres with lateral dimensions of 18.9 × 18.5 Ų and a height of about 8 Å. The hemispheres are centered by a UO₈ hexagonal bipyramid surrounded by six dimers of Cr⁵⁺O₅ square pyramids, UO₇ pentagonal bipyramids, and Cr⁶⁺O₄ tetrahedra. The hemispheres are linked into two-dimensional layers so that two adjacent hemispheres are oriented in opposite directions relative to the plane of the layer. From a topological point of view, the hemispheres have the formula U₂₁Cr₂₃ and can be considered as derivatives of nanospherical cluster U₂₆Cr₃₆ composed of three-, four-, and five-membered rings