134 research outputs found
ロバストパラメータ設計における統計的方法論の開発
Open House, ISM in Tachikawa, 2011.7.14統計数理研究所オープンハウス(立川)、H23.7.14ポスター発
パラメータ設計における統計数理的方法論の開発
Open House, ISM in Tachikawa, 2013.6.14統計数理研究所オープンハウス(立川)、H25.6.14ポスター発
AKARI Infrared Camera Survey of the Large Magellanic Cloud. I. Point Source Catalog
We present a near- to mid-infrared point source catalog of 5 photometric
bands at 3.2, 7, 11, 15 and 24 um for a 10 deg2 area of the Large Magellanic
Cloud (LMC) obtained with the Infrared Camera (IRC) onboard the AKARI
satellite. To cover the survey area the observations were carried out at 3
separate seasons from 2006 May to June, 2006 October to December, and 2007
March to July.
The 10-sigma limiting magnitudes of the present survey are 17.9, 13.8, 12.4,
9.9, and 8.6 mag at 3.2, 7, 11, 15 and 24 um, respectively. The photometric
accuracy is estimated to be about 0.1 mag at 3.2 um and 0.06--0.07 mag in the
other bands. The position accuracy is 0.3" at 3.2, 7 and 11um and 1.0" at 15
and 24 um. The sensitivities at 3.2, 7, and 24 um are roughly comparable to
those of the Spitzer SAGE LMC point source catalog, while the AKARI catalog
provides the data at 11 and 15 um, covering the mid-infrared spectral range
contiguously. Two types of catalog are provided: a Catalog and an Archive. The
Archive contains all the detected sources, while the Catalog only includes the
sources that have a counterpart in the Spitzer SAGE point source catalog. The
Archive contains about 650,000, 140,000, 97,000, 43,000, and 52,000 sources at
3.2, 7, 11, 15, and 24 um, respectively. Based on the catalog, we discuss the
luminosity functions at each band, the color-color diagram, and the
color-magnitude diagram using the 3.2, 7, and 11 um band data. Stars without
circumstellar envelopes, dusty C-rich and O-rich stars, young stellar objects,
and background galaxies are located at distinct regions in the diagrams,
suggesting that the present catalog is useful for the classification of objects
towards the LMC.Comment: 59 pages, 12 figures, accepted for the Astronomical Journa
Potential endocrine effects of hypothalamic peptide "neurotensin" on pancreas in dogs
Effects of synthetic neurotensin on the endocrine pancreas were studied in nine normal and six hypophysectomized (10th to 14th day post-hypophysectomy) dogs. Synthetic neurotensin was administered into the superior pancreaticoduodenal artery, and plasma insulin and glucagon concentrations were measured radioimmunologically. In normal dogs, ten microgram/kg neurotensin administration brought about a mild hyperglycemic response and sharp and rapid increase of plasma insulin and glucagon concentrations in the superior pancreaticoduodenal vein. A biphasic insulin response was noted in the pancreatic vein. The results suggest that a large dose of neurotensin acts directly on the endocrine pancreas causing secretion of these hormones. In hypophysectomized dogs, basal levels of plasma insulin and glucagon were decreased and neurotensin had little effect on the endocrine pancreas even with the administration of a large dose.</p
A Distinct Subset of Fibroblastic Stromal Cells Constitutes the Cortex-Medulla Boundary Subcompartment of the Lymph Node
The spatiotemporal regulation of immune responses in the lymph node (LN) depends on its sophisticated tissue architecture, consisting of several subcompartments supported by distinct fibroblastic stromal cells (FSCs). However, the intricate details of stromal structures and associated FSC subsets are not fully understood. Using several gene reporter mice, we sought to discover unrecognized stromal structures and FSCs in the LN. The four previously identified FSC subsets in the cortex are clearly distinguished by the expression pattern of reporters including PDGFRβ, CCL21-ser, and CXCL12. Herein, we identified a unique FSC subset expressing both CCL21-ser and CXCL12 in the deep cortex periphery (DCP) that is characterized by preferential B cell localization. This subset was clearly different from CXCL12highLepRhigh FSCs in the medullary cord, which harbors plasma cells. B cell localization in the DCP was controlled chiefly by CCL21-ser and, to a lesser extent, CXCL12. Moreover, the optimal development of the DCP as well as medulla requires B cells. Together, our findings suggest the presence of a unique microenvironment in the cortex-medulla boundary and offer an advanced view of the multi-layered stromal framework constructed by distinct FSC subsets in the LN
Lymph Node Stromal Cell Subsets
The spatiotemporal regulation of immune responses in the lymph node (LN) depends on its sophisticated tissue architecture, consisting of several subcompartments supported by distinct fibroblastic stromal cells (FSCs). However, the intricate details of stromal structures and associated FSC subsets are not fully understood. Using several gene reporter mice, we sought to discover unrecognized stromal structures and FSCs in the LN. The four previously identified FSC subsets in the cortex are clearly distinguished by the expression pattern of reporters including PDGFRb, CCL21-ser, and CXCL12. Herein, we identified a unique FSC subset expressing both CCL21-ser and CXCL12 in the deep cortex periphery (DCP) that is characterized by preferential B cell localization. This subset was clearly different fromCXCL12highLepRhigh FSCs in themedullary cord, which harbors plasma cells. B cell localization in the DCP was controlled chiefly by CCL21-ser and, to a lesser extent, CXCL12. Moreover, the optimal development of the DCP as well as medulla requires B cells. Together, our findings suggest the presence of a unique microenvironment in the cortex-medulla boundary and offer an advanced view of the multi-layered stromal framework constructed by distinct FSC subsets in the LN
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